Two-Step Hypothesis Testing When the Number of Variables Exceeds the Sample Size

Medical images and genetic assays typically generate data with more variables than subjects. Scientists may use a two-step approach for testing hypotheses about Gaussian mean vectors. In the first step, principal components analysis (PCA) selects a set of sample components fewer in number than the sample size. In the second step, applying classical multivariate analysis of variance (MANOVA) methods to the reduced set of variables provides the desired hypothesis tests. Simulation results presented here indicate that success of the PCA in the first step requires nearly all variation to occur in population components far fewer in number than the number of subjects. In the second step, multivariate tests fail to attain reasonable power except in restrictive, favorable cases. The results encourage using other approaches discussed in the article to provide dependable hypothesis testing with high dimension, low sample size data (HDLSS).     

On approximating a linear combination of central wishart matrices with positive coefficients

Consider linear combinations of central Wishart matrices with positive coefficients. By equating the expected values and the generalized variance of variances and covariances, we propose approximating the distributions of those linear combinations by central Wishart distributions. Some Monte Carlo results are given to demonstrate the closeness of this approximation.     

A monte carlo study of the power of alternative tests under the generalized manova model

Monte Carlo simulations are performed for a broad range of conditions. These simulations indicate that the powers of alternative tests under the generalized MANOVA model for small samples differ significantly, if a large reduction of the number of polynomial parameters is applied. The results show that, if the response covariance matrix ∑ is known, the best alternative is to use ∑. If, however, ∑ is unknown, substitution of an identity matrix for ∑ is recommended. This alternative usually results in a test with more power than the test with the usual estimate of ∑ employing covariates or the test with an estimate of E obtained from another sample.     

Properties of a randomization test for multifactor comparisons of groups

Multivariate hypothesis testing in studies of vegetation is likely to be hindered by unrealistic assumptions when based on conventional statistical methods. This can be overcome by randomization tests. In this paper, the accuracy and power of a MANOVA randomization test are evaluated for one and two factors with interaction with simulated data from three distributions. The randomization test is based on the partitioning of sum of squares computed from Euclidean distances. In one-factor designs, sample size and variance inequality were evaluated. The results showed a high level of accuracy. The power curve was higher with normal distribution, lower with uniform, intermediate with lognormal and was sensitive to variance inequality. In two-factor designs, three methods of permutations and two statistics were compared. The results showed that permutation of the residuals with F _pseudo is accurate and can give good power for testing the interaction and restricted permutation for testing main factors.     

General multivariate linear models for longitudional studies

Longitudinal studies occcur frequently in many different disciplines. To fully utilize the potential value of the information contained in a longitudinal data, various multivariate linear models have been proposed. The methodology and analysis are somewhat unique in their own ways and their relationships are not well understood and presented. This article describes a general multivaritate linear model for longitudinal data and attempts to provide a constructive formulation of the components in the mean response profile. The objective is to point out the extension and connections of some well-known models that have been obscured by different areas of application. More imporiantly, the model is expressed in a unified regression form from the subject matter considerations. Such an approach is simpler and more intuitive than other ways to modeling and parameter estimation. As a cmsequeace the analyses of the general class cf models for longitudional data can be casily implemented with standard software.     

Manova with covariates and an application in profile analysis

Replacing one of the two marginal distributions in a bivariate normal by a family of symmetrical distributions, we obtain a new family of symmetric bivariate distributions. We use the Tiku - Suresh (1990) method to estimate the parameters of this new bivariate family. We define a Hotelling - type statistic to test the mean vector and evaluate the asymptotic power of this statistic relative to the Hotelling T² statistic. We show that the former is considerably more powerful.     

大学生学业情绪及其与学业自我效能的关系

采用学业情绪问卷（AEQ）和学业自我效能量表（ASQ）,随机取样某高校350名大学生作为被试进行测试,探讨大学生学业情绪及其与学业自我效能的关系。结果显示：①大学生的总体学业情绪在中等水平以上;②女生在沮丧上显著高于男生;大一学生在焦虑上显著高于大三,在心烦疲乏上显著高于大二;③不同学业自我效能水平上大学生学业情绪存在显著差异;学业自我效能与学业情绪各维度存在显著地相关;④回9-2分析表明,学业自我效能各因子对学业情绪各维度具有显著地预测作用。大学生的学业自我效能是影响其学业情绪的重要因素。     

Manova double linear hypothesis with double linear restrictions

Given the usual normal multivariate linear regression model Y = BX + E, with B subjected to double linear restrictions GBF' = T, a likelihood ratio test criterion for testing the composite linear null hypothesis HBJ' = U; G, F, T, H, J, U specified, is provided. The applications of such tests are discussed by Timm (1980).     

a bayesian analysis of the multivariate mixed-linear model

The Bayesian analysis of the multivariate mixed linear model is considered. The exact posterior distribution for the fixed effects matrix and the error covariance matrix are obtained. The exact posterior means and variances of the Bayesian estimators for the covariance matrices of random effects are also derived. These posterior moments are computed without constrained optimization and numerical integration. The calculations are feasible for arbitrary models. Reasonable approximations for the posterior distributions for the covariance matrices associated with the random effects are obtained also. Results are illustrated with a numerical example.     

Analyzing Designed Experiments with Multiple Responses

This paper is an overview of a unified framework for analyzing designed experiments with univariate or multivariate responses. Both categorical and continuous design variables are considered. To handle unbalanced data, we introduce the so-called Type II* sums of squares. This means that the results are independent of the scale chosen for continuous design variables. Furthermore, it does not matter whether two-level variables are coded as categorical or continuous. Overall testing of all responses is done by 50-50 MANOVA, which handles several highly correlated responses. Univariate p-values for each response are adjusted by using rotation testing. To illustrate multivariate effects, mean values and mean predictions are illustrated in a principal component score plot or directly as curves. For the unbalanced cases, we introduce a new variant of adjusted means, which are independent to the coding of two-level variables. The methodology is exemplified by case studies from cheese and fish pudding production.