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In this study, we provide the Farlie–Gumbel–Morgenstern bivariate copula of rth and sth order statistics. The main emphasis in this study is on the inference procedure which is based on the maximum pseudo-likelihood estimate for the copula parameter. As for the methodology, goodness-of-fit test statistic for copulas which is based on a Cramér–von Mises functional of the empirical copula process is applied for selecting an appropriate model by bootstrapping. An application of the methodology to simulated data set is also presented.  相似文献   
213.
ABSTRACT

In biomedical and epidemiological studies, gene–environment (G–E) interactions have been shown to importantly contribute to the etiology and progression of many complex diseases. Most existing approaches for identifying G–E interactions are limited by the lack of robustness against outliers/contaminations in response and predictor spaces. In this study, we develop a novel robust G–E identification approach using the trimmed regression technique under joint modelling. A robust data-driven criterion and stability selection are adopted to determine the trimmed subset which is free from both vertical outliers and leverage points. An effective penalization approach is developed to identify important G–E interactions, respecting the ‘main effects, interactions’ hierarchical structure. Extensive simulations demonstrate the better performance of the proposed approach compared to multiple alternatives. Interesting findings with superior prediction accuracy and stability are observed in the analysis of The Cancer Genome Atlas data on cutaneous melanoma and breast invasive carcinoma.  相似文献   
214.
In countries, where a substantial proportion of retirement income rests on savings, there is much concern that a sizeable fraction of the population reaches retirement with insufficient financial resources. We define saving regret as the wish in hindsight to have saved more earlier in life. We measured saving regret and possible determinants in a survey of U.S. households in which respondents were aged 60–79. We find high levels of saving regret, affirmed by some 58%. Saving regret exhibits significant and plausible correlations with personal characteristics and wealth: Married, older, healthier and wealthier respondents are less likely to report saving regret, suggesting the measure’s validity. We find only weak evidence for correlations between saving regret and measures of procrastination: persons with traits associated with procrastination express saving regret about as often as those without those traits.  相似文献   
215.
When does trade become a one-way relationship? We study bilateral trade balances for a sample of 18 European countries over the period from 1948 through 2008. We find that, with the introduction of the euro, trade imbalances among euro area members widened considerably, even after allowing for permanent asymmetries in trade competitiveness within pairs of countries or in the overall trade competitiveness of individual countries. This is consistent with indications that pair-wise trade tends to be more balanced when nominal exchange rates are flexible. Intra-euro area imbalances also seem to have become more persistent with the introduction of the euro, some of which is linked to labor market inflexibility. Reviewing the direction of imbalances, we find that bilateral trade surpluses are decreasing in the real exchange rate, decreasing in growth differentials, and increasing in the relative volatility of national business cycles. Finally, countries with relatively higher fiscal deficits and less flexible labor and product markets exhibit systematically lower trade surpluses than others.  相似文献   
216.
The relation between citizenship and labor market position is complex. Besides a causal impact from citizenship towards labor market position, several selection mechanisms may cause particular immigrants to choose for naturalization. We investigate the empirical relation on the basis of German and Dutch survey data. For the Netherlands we find a positive relation between citizenship and labor market position, while for Germany we find mixed results as citizenship is negatively related to tenured employment. The contrasting results may be explained by institutional differences. In Germany, economic self-reliance is more strictly required for naturalization than in the Netherlands. This may lead to a stronger incentive to naturalize for workers with a temporary contract in Germany.  相似文献   
217.
To date little has been known, and less written, about the life of Hugh George Brennan, Glasgow University's first lecturer in Russian. The uncovering of previously unused Russian and British sources throwing fresh light on his life, intellectual development and occupations has made possible a fuller assessment of a significant figure in Glasgow's contribution to Slavonic Studies. Brennan lived and taught in Russia for 20 years. The resulting intense and unusually intimate experience of Russian life probably explains unconventional aspects of his Glasgow appointment. Brennan was an undoubted educational and social success in Russia. Events in the shape of the February Revolution of 1917 forced him to return to Britain. Glasgow's timely offer of a new position was the start of a very different life. This aspect of Brennan's career is reviewed mainly through his commitment to extensive public activities.  相似文献   
218.
ObjectiveTo develop a framework for evaluating and monitoring a primary health care service, integrating hospital and community services.MethodA targeted literature review of primary health service evaluation frameworks was performed to inform the development of the framework specifically for remote communities. Key principles underlying primary health care evaluation were determined and sentinel indicators developed to operationalise the evaluation framework. This framework was then validated with key stakeholders.ResultsThe framework includes Donabedian's three seminal domains of structure, process and outcomes to determine health service performance. These in turn are dependent on sustainability, quality of patient care and the determinants of health to provide a comprehensive health service evaluation framework. The principles underpinning primary health service evaluation were pertinent to health services in remote contexts. Sentinel indicators were developed to fit the demographic characteristics and health needs of the population. Consultation with key stakeholders confirmed that the evaluation framework was applicable.ConclusionData collected routinely by health services can be used to operationalise the proposed health service evaluation framework. Use of an evaluation framework which links policy and health service performance to health outcomes will assist health services to improve performance as part of a continuous quality improvement cycle.  相似文献   
219.
This study examines the effect of board size on the economic impact of bank mergers and acquisitions (M&A) in the US. Using a hand-collected dataset of 508 M&A between 2012 and 2018, we find that board size is negatively related to acquirer excess returns. In an additional analysis, we show that large boards have positive value implications for banks that combine the CEO and chairman roles as well as for large banks. Our findings indicate that a “one-size-fits-all” approach to board size is not necessarily in the interests of shareholders; instead, a more flexible and proactive formulation is needed.  相似文献   
220.
Access to a regular primary care provider is essential to quality care. In Canada, where 15 % of patients are unattached (i.e., without a regular provider), centralized waiting lists (CWLs) help attach patients to a primary care provider (family physician or nurse practitioner). Previous studies reveal mechanisms needed for CWLs to work, but focus mostly on CWLs for specialized health care. We aim to better understand how to design CWLs for unattached patients in primary care.In this study, a logic analysis compares empirical evidence from a qualitative case study of CWLs for unattached patients in seven Canadian provinces to programme theory derived from a realist review on CWLs. Data is analyzed using context-intervention-mechanism-outcome configurations.Results identify mechanisms involved in three components of CWL design: patient registration, patient prioritization, and patient assignment to a provider for attachment. CWL programme theory is revised to integrate mechanisms specific to primary care, where patients, rather than referring providers, are responsible for registering on the CWL, where prioritization must consider a broad range of conditions and characteristics, and where long-term acceptability of attachment is important. The study provides new insight into mechanisms that enable CWLs for unattached patients to work.  相似文献   
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