Robust designs for experiments with blocks

ABSTRACT

For experiments running in field plots or over time, the observations are often correlated due to spatial or serial correlation, which leads to correlated errors in a linear model analyzing the treatment means. Without knowing the exact correlation matrix of the errors, it is not possible to compute the generalized least-squares estimator for the treatment means and use it to construct optimal designs for the experiments. In this paper, we propose to use neighborhoods to model the covariance matrix of the errors, and apply a modified generalized least-squares estimator to construct robust designs for experiments with blocks. A minimax design criterion is investigated, and a simulated annealing algorithm is developed to find robust designs. We have derived several theoretical results, and representative examples are presented.     

Robustness of subset response surface designs to missing observations

Experiments designed to investigate the effect of several factors on a process have wide application in modern industrial and scientific research. Response surface designs allow the researcher to model the effects of the input variables on the response of the process. Missing observations can make the results of a response surface experiment quite misleading, especially in the case of one-off experiments or high cost experiments. Designs robust to missing observations can attract the user since they are comparatively more reliable. Subset designs are studied for their robustness to missing observations in different experimental regions. The robustness of subset designs is also improved for multiple levels by using the minimax loss criterion.     

Monotonic minimax estimators of a 2×2 covariance matrix

Let S : 2 × 2 have a nonsingular Wishart distribution with unknown matrix σ and n degrees of freedom. For estimating σ two families of mimmax estimators, with respect to the entropy loss, are presented. These estimators are of the form σ(S) = Rø(L)R^t where R is orthogonal, L and Φ are diagonal, and RLR^T = S. Conditions under which the components of Φ and L follow the same order relation [i.e., writing Φ = diag(Φ₁,Φ₂) and L = diag(l₁,/₂) with l₁ ≥ l₂, we have Φ₁ ≥ Φ₂] are established. Comparisons with Stein's estimators and other orthogonally invariant estimators are discussed.     

The Minimaxity of the Mid P-value under Linear and Squared Loss Functions

The mid-p is defined as the sum of the probabilities of all outcomes more extreme than an observed value, plus half of the probabilities of all outcomes exactly as extreme. On the one hand, it offers greater power than the standard p-value, but on the other, tests based on the mid-p statistic may have greater Type I error than their nominal level. This article investigates the mid p-value's properties under the estimated truth paradigm, which views p-values as estimators of the truth. The mid-p is shown to minimize the maximum risk for one-sided and two-sided tests.     

Minimax designs for 2k factorial experiments for generalized linear models

ABSTRACT

Formulas for A- and C-optimal allocations for binary factorial experiments in the context of generalized linear models are derived. Since the optimal allocations depend on GLM weights, which often are unknown, a minimax strategy is considered. This is shown to be simple to apply to factorial experiments. Efficiency is used to evaluate the resulting design. In some cases, the minimax design equals the optimal design. For other cases no general conclusion can be drawn. An example of a two-factor logit model suggests that the minimax design performs well, and often better than a uniform allocation.     

Admissible minimax estimators for the shape parameter of Topp–Leone distribution

Abstract

The shape parameter of Topp–Leone distribution is estimated in this article from the Bayesian viewpoint under the assumption of known scale parameter. Bayes and empirical Bayes estimates of the unknown parameter are proposed under non informative and suitable conjugate priors. These estimates are derived under the assumption of squared and linear-exponential error loss functions. The risk functions of the proposed estimates are derived in analytical forms. It is shown that the proposed estimates are minimax and admissible. The consistency of the proposed estimates under the squared error loss function is also proved. Numerical examples are provided.