A note on the adaptive control of false discovery rates

Summary.  The use of a fixed rejection region for multiple hypothesis testing has been shown to outperform standard fixed error rate approaches when applied to control of the false discovery rate. In this work it is demonstrated that, if the original step-up procedure of Benjamini and Hochberg is modified to exercise adaptive control of the false discovery rate, its performance is virtually identical to that of the fixed rejection region approach. In addition, the dependence of both methods on the proportion of true null hypotheses is explored, with a focus on the difficulties that are involved in the estimation of this quantity.     

Analysis of longitudinal multiple-source binary data using generalized estimating equations

Summary.  We present a multivariate logistic regression model for the joint analysis of longitudinal multiple-source binary data. Longitudinal multiple-source binary data arise when repeated binary measurements are obtained from two or more sources, with each source providing a measure of the same underlying variable. Since the number of responses on each subject is relatively large, the empirical variance estimator performs poorly and cannot be relied on in this setting. Two methods for obtaining a parsimonious within-subject association structure are considered. An additional complication arises with estimation, since maximum likelihood estimation may not be feasible without making unrealistically strong assumptions about third- and higher order moments. To circumvent this, we propose the use of a generalized estimating equations approach. Finally, we present an analysis of multiple-informant data obtained longitudinally from a psychiatric interventional trial that motivated the model developed in the paper.     

Multiple reference points in investor regret

Regret is the result of a comparison between “what is” and “what might have been”. Although regret is a relevant emotion in the life of investors, research studying the regrets of real investors and how these are influenced by multiple reference points is lacking. We present a field survey that investigated the regrets of real stock investors in relation to multiple “what might have been’s.” We found that their regrets are most influenced by what their outcomes might have been had they not invested, by their expected outcomes and by the best-performing unchosen stocks. In addition, we also found that the feeling of regret was influenced by losses or gains relative to each reference point rather than by the size of the loss or gain.     

经济不发达地区多系统图书馆协调发展模式初探

多系统图书馆协调发展的前提是建立在一种利益均衡机制上的横向联合，针对不同地区的经济发展状况而呈现出多种表象，如何把握本地区多系统图书馆之间的利益均衡，需要建立哪些激励机制和运转机制，同协调之后所要达到的预期效果密切相关。     

毕业生分配规划模型初探

本文阐述系统工程方法在上海市1987—1990年大学毕业生分配规划中的应用。通过建立数学模型及其形式变换,给出了两种不同的运算结果,并根据综合指标分别对结果进行了分析和评价。分析结果表明,推荐方案的总体偏差只有原方案的五分之一。     

A Multiple Imputation Approach to the Analysis of Current Status Data with the Additive Hazards Model

This article discusses regression analysis of current status data, which occur in many fields including cross-sectional studies, demographical investigations, and tumorigenicity experiments (Keiding, 1991 Keiding , N. ( 1991 ). Age-specific incidence and prevalence: a statistical perspective (with discussion) . J. Roy. Statist. Soc. Ser. A 154 : 371 – 412 .[Crossref] , [Google Scholar]; Sun 2006 Sun , J. ( 2006 ). The Statistical Analysis of Interval-Censored Failure Time Data . New York : Springer-Verlag . [Google Scholar]). For the problem, we focus on the situation where the survival time of interest can be described by the additive hazards model and a multiple imputation approach is presented for inference. A major advantage of the approach is its simplicity and it can be easily implemented by using the existing software packages for right-censored failure time data. Extensive simulation studies are conducted and indicate that the approach performs well for practical situations and is comparable to the existing methods. The methodology is applied to a set of current status data arising from a tumorigenicity experiment and the model checking is discussed.     

Mixed Graphical Model Selection Using Holm's Procedure

The problem of selecting a graphical model is considered as a performing simultaneously multiple tests. The control of the overall Type I error on the selected graph is done using the so famous Holm's procedure. We prove that when we use a consistent edge exclusion test the selected graph is asymptotically equal to the true graph with probability at least equal to a fixed level 1 ? α. This method is then used for the selection of mixed concentration graph models by performing the χ²-edge exclusion test. We also apply the method to two classical examples and to simulated data. We compare the overall error of the selected model with the one obtained using the stepwise method. We establish that the control is better when we use the Holm's procedure.     

Application of Multiple Imputation in Analysis of Data from Clinical Trials with Treatment Related Dropouts

This article develops a functional form of the generalized Poisson regression model that parametrically nests the Poisson and the two well known generalized Poisson regression models (GP-1 and GP-2). The proposed model is applied on the Malaysian motor insurance claim count data.     

A New Control Scheme Always Better Than X-Bar Chart

A new control scheme is proposed by borrowing the idea of the Benjamini–Hochberg procedure for controlling the false discovery rate in multiple testing. It is shown theoretically that the proposed 2-span control scheme outperforms the Shewhart X-bar chart in terms of the average run length under any size of mean shifts. Some simulations are carried out to demonstrate that the proposed scheme having various span sizes always outperforms the X-bar chart in terms of the average run lengths.