Approximations to the multivariate normal integral

We propose a simple and efficient way to approximate multivariate normal probabilities using univariate and bivariate probabilities. The approximation is computationally tested for the trivariate and quadrivariate normal probabilities. A few problems of higher dimensions were also tested.     

Small sample properties of parameter estimation in the dirichlet distribution

A numerically feasible algorithm is proposed for maximum likelihood estimation of the parameters of the Dirichlet distribution. The performance of the proposed method is compared with the method of moments using bias ratio and squared errors by Monte Carlo simulation. For these criteria, it is found that even in small samples maximum likelihood estimation has advantages over the method of moments.     

Bayesian classification with multivariate autoregressive sources that might have different orders

The main objective of this paper is to develop an exact Bayesian technique that can be used to assign a multivariate time series realization to one of several autoregressive sources, with unknown coefficients and precision, that might have different orders. The foundation of the proposed technique is to develop the posterior mass function of a classification vector, in an easy form, using the conditional likelihood function. A multivariate time series realization is assigned to the multivariate autoregressive source with the largest posterior probability. A simulation study, with uniform prior mass function, is carried out to demonstrate the performance of the proposed technique and to test its adequacy in handling the multivariate classification problems. The analysis of the numerical results supports the adequacy of the proposed technique in solving the classification problems with multivariate autoregressive sources.     

The estimation of treatment effect for the censored bivariate data under the univariate censoring

This paper establishes a nonparametric estimator for the treatment effect on censored bivariate data under unvariate censoring. This proposed estimator is based on the one from Lin and Ying(1993)'s nonparametric bivariate survival function estimator, which is itself a generalized version of Park and Park(1995)' quantile estimator. A Bahadur type representation of quantile functions were obtained from the marginal survival distribution estimator of Lin and Ying' model. The asymptotic property of this estimator is shown below and the simulation studies are also given     

A class of semiparametric transormation frailty models with application to estimating treatment effects and heterogenity in aids clinical traials

Muitivariate failure time data are common in medical research; com¬monly used statistical models for such correlated failure-time data include frailty and marginal models. Both types of models most often assume pro¬portional hazards (Cox, 1972); but the Cox model may not fit the data well This article presents a class of linear transformation frailty models that in¬cludes, as a special case, the proportional hazards model with frailty. We then propose approximate procedures to derive the best linear unbiased es¬timates and predictors of the regression parameters and frailties. We apply the proposed methods to analyze results of a clinical trial of different dose levels of didansine (ddl) among HIV-infected patients who were intolerant of zidovudine (ZDV). These methods yield estimates of treatment effects and of frailties corresponding to patient groups defined by clinical history prior to entry into the trial.     

A generalization of the compound rayleigh distribution: using a bayesian method on cancer survival times

In this paper the generalized compound Rayleigh model, exhibiting flexible hazard rate, is high¬lighted. This makes it attractive for modelling survival times of patients showing characteristics of a random hazard rate. The Bayes estimators are derived for the parameters of this model and some survival time parameters from a right censored sample. This is done with respect to conjugate and discrete priors on the parameters of this model, under the squared error loss function, Varian's asymmetric linear-exponential (linex) loss function and a weighted linex loss function. The future survival time of a patient is estimated under these loss functions. A Monte Carlo simu¬lation procedure is used where closed form expressions of the estimators cannot be obtained. An example illustrates the proposed estimators for this model.     

Estimation and Test for Multi-Dimensional Regression Models

This work is concerned with the estimation of multi-dimensional regression and the asymptotic behavior of the test involved in selecting models. The main problem with such models is that we need to know the covariance matrix of the noise to get an optimal estimator. We show in this article that if we choose to minimize the logarithm of the determinant of the empirical error covariance matrix, then we get an asymptotically optimal estimator. Moreover, under suitable assumptions, we show that this cost function leads to a very simple asymptotic law for testing the number of parameters of an identifiable and regular regression model. Numerical experiments confirm the theoretical results.     

A New Goodness-of-Fit Test Based on the Empirical Characteristic Function

In this article, we present a goodness-of-fit test for a distribution based on some comparisons between the empirical characteristic function c_n(t) and the characteristic function of a random variable under the simple null hypothesis, c₀(t). We do this by introducing a suitable distance measure. Empirical critical values for the new test statistic for testing normality are computed. In addition, the new test is compared via simulation to other omnibus tests for normality and it is shown that this new test is more powerful than others.     

A Multivariate Adaptive Exponentially Weighted Moving Average Control Chart

A multivariate extension of the adaptive exponentially weighted moving average (AEWMA) control chart is proposed. The new multivariate scheme can detect small and large shifts in the process mean vector effectively. The proposed scheme can be viewed as a smooth combination of a multivariate exponentially weighted moving average (MEWMA) chart and a Shewhart χ²-chart. The optimal design of the proposed chart is given according to a pre-specified in-control average run length and two shift sizes; a small and large shift each measured in terms of the non centrality parameter. The signal resistance of the newly proposed multivariate chart is also given. Comparisons among the new chart, the MEWMA chart, and the combined Shewhart-MEWMA (S-MEWMA) chart in terms of the standard and worst-case average run length profiles are presented. In addition, the three charts are compared with respect to their worst-case signal resistance values. The proposed chart gives somewhat better worst-case ARL and signal resistance values than the competing charts. It also gives better standard ARL performance especially for moderate and large shifts. The effectiveness of our proposed chart is illustrated through an example with simulated data set.     

Estimation of Survivorship Function Based on Doubly Censored Data with Application to HIV/AIDS

Left censoring concept has been defined in different ways in statistical applications. Turnbull (1974 Turnbull , B. W. ( 1974 ). Nonparametric estimation of a survivorship function with doubly censored data . J. Amer. Statist. Assoc. 69 : 169 – 173 .[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]) defines it in a particular way. Whereas in recent literature, especially in epidemiological studies, it has been defined in another way. This difference between the two approaches is the main reason that despite simplicity, Turnbull method cannot be applicable in all cases of doubly censored data. In this article we present a modified Turnbull method for analysis of doubly censored data adequate with recent definition. Comparison has been done with other statistical methods, including imputation estimator, full likelihood-based and conditional likelihood-based approach using Iranian HIV data.