Least squares estimation of varying‐coefficient hazard regression with application to breast cancer dose‐intensity data

To enhance modeling flexibility, the authors propose a nonparametric hazard regression model, for which the ordinary and weighted least squares estimation and inference procedures are studied. The proposed model does not assume any parametric specifications on the covariate effects, which is suitable for exploring the nonlinear interactions between covariates, time and some exposure variable. The authors propose the local ordinary and weighted least squares estimators for the varying‐coefficient functions and establish the corresponding asymptotic normality properties. Simulation studies are conducted to empirically examine the finite‐sample performance of the new methods, and a real data example from a recent breast cancer study is used as an illustration. The Canadian Journal of Statistics 37: 659–674; 2009 © 2009 Statistical Society of Canada     

Estimation of Nonparametric Models With Simultaneity

We introduce methods for estimating nonparametric, nonadditive models with simultaneity. The methods are developed by directly connecting the elements of the structural system to be estimated with features of the density of the observable variables, such as ratios of derivatives or averages of products of derivatives of this density. The estimators are therefore easily computed functionals of a nonparametric estimator of the density of the observable variables. We consider in detail a model where to each structural equation there corresponds an exclusive regressor and a model with one equation of interest and one instrument that is included in a second equation. For both models, we provide new characterizations of observational equivalence on a set, in terms of the density of the observable variables and derivatives of the structural functions. Based on those characterizations, we develop two estimation methods. In the first method, the estimators of the structural derivatives are calculated by a simple matrix inversion and matrix multiplication, analogous to a standard least squares estimator, but with the elements of the matrices being averages of products of derivatives of nonparametric density estimators. In the second method, the estimators of the structural derivatives are calculated in two steps. In a first step, values of the instrument are found at which the density of the observable variables satisfies some properties. In the second step, the estimators are calculated directly from the values of derivatives of the density of the observable variables evaluated at the found values of the instrument. We show that both pointwise estimators are consistent and asymptotically normal.     

Penalized proportion estimation for non parametric mixture of regressions

Abstract

In this article, we propose a penalized local log-likelihood method to locally select the number of components in non parametric finite mixture of regression models via proportion shrinkage method. Mean functions and variance functions are estimated simultaneously. We show that the number of components can be estimated consistently, and further establish asymptotic normality of functional estimates. We use a modified EM algorithm to estimate the unknown functions. Simulations are conducted to demonstrate the performance of the proposed method. We illustrate our method via an empirical analysis of the housing price index data of United States.     

Conditional VAR and Expected Shortfall: A New Functional Approach

We estimate two well-known risk measures, the value-at-risk (VAR) and the expected shortfall, conditionally to a functional variable (i.e., a random variable valued in some semi(pseudo)-metric space). We use nonparametric kernel estimation for constructing estimators of these quantities, under general dependence conditions. Theoretical properties are stated whereas practical aspects are illustrated on simulated data: nonlinear functional and GARCH(1,1) models. Some ideas on bandwidth selection using bootstrap are introduced. Finally, an empirical example is given through data of the S&P 500 time series.     

中国生产性服务业TFP的时空差异与影响因素分析

在利用Malmquist指数法测算2005-2013年中国30个省份生产性服务业的全要素生产率(TFP)的基础上,采用核密度估计法分析了TFP的动态演变,并运用分位数回归方法对中国生产性服务业TFP的影响因素进行了实证分析。研究发现:在考察期内中国生产性服务业TFP总体呈下降态势,技术效率下降是其下降的主要原因;核密度曲线说明中国生产性服务业TFP省际差距扩大,技术效率和技术进步逐渐呈现两极分化的趋势;分位数回归结果表明,工业化水平和人力资本水平对生产性服务业TFP提升具有普遍的促进作用,而信息化水平、对外开放水平、制造业集中度对生产性服务业TFP提高的贡献大小均与地区生产性服务业TFP的水平有关。     

Subsampling-extrapolation bandwidth selection in bivariate kernel density estimation

This paper focuses on bivariate kernel density estimation that bridges the gap between univariate and multivariate applications. We propose a subsampling-extrapolation bandwidth matrix selector that improves the reliability of the conventional cross-validation method. The proposed procedure combines a U-statistic expression of the mean integrated squared error and asymptotic theory, and can be used in both cases of diagonal bandwidth matrix and unconstrained bandwidth matrix. In the subsampling stage, one takes advantage of the reduced variability of estimating the bandwidth matrix at a smaller subsample size m (m < n); in the extrapolation stage, a simple linear extrapolation is used to remove the incurred bias. Simulation studies reveal that the proposed method reduces the variability of the cross-validation method by about 50% and achieves an expected integrated squared error that is up to 30% smaller than that of the benchmark cross-validation. It shows comparable or improved performance compared to other competitors across six distributions in terms of the expected integrated squared error. We prove that the components of the selected bivariate bandwidth matrix have an asymptotic multivariate normal distribution, and also present the relative rate of convergence of the proposed bandwidth selector.     

Kernel density estimation under negative superadditive dependence and its application for real data

In this paper, the kernel density estimator for negatively superadditive dependent random variables is studied. The exponential inequalities and the exponential rate for the kernel estimator of density function with a uniform version, over compact sets are investigated. Also, the optimal bandwidth rate of the estimator is obtained using mean integrated squared error. The results are generalized and used to improve the ones obtained for the case of associated sequences. As an application, FGM sequences that fulfil our assumptions are investigated. Also, the convergence rate of the kernel density estimator is illustrated via a simulation study. Moreover, a real data analysis is presented.     

Non-parametric estimation of reciprocal coordinate subtangent for right censored dependent scheme

The concept of reciprocal coordinate subtangent (RCST) has been used as a useful tool to study the monotone behavior of a continuous density function and for characterizing probability distributions. In this paper, we propose a non-parametric estimator for RCST based on the censored dependent data. Asymptotic properties of the estimator are established under suitable regularity conditions. A simulation study is carried out to examine the performance of the estimator. The usefulness of the estimator is also examined through a real data.     

Cytometry inference through adaptive atomic deconvolution

In this paper, we consider a statistical estimation problem known as atomic deconvolution. Introduced in reliability, this model has a direct application when considering biological data produced by flow cytometers. From a statistical point of view, we aim at inferring the percentage of cells expressing the selected molecule and the probability distribution function associated with its fluorescence emission. We propose here an adaptive estimation procedure based on a previous deconvolution procedure introduced by Es, Gugushvili, and Spreij [(2008), ‘Deconvolution for an atomic distribution’, Electronic Journal of Statistics, 2, 265–297] and Gugushvili, Es, and Spreij [(2011), ‘Deconvolution for an atomic distribution: rates of convergence’, Journal of Nonparametric Statistics, 23, 1003–1029]. For both estimating the mixing parameter and the mixing density automatically, we use the Lepskii method based on the optimal choice of a bandwidth using a bias-variance decomposition. We then derive some convergence rates that are shown to be minimax optimal (up to some log terms) in Sobolev classes. Finally, we apply our algorithm on the simulated and real biological data.     

Kernel naive Bayes discrimination for high‐dimensional pattern recognition

Kernel discriminant analysis translates the original classification problem into feature space and solves the problem with dimension and sample size interchanged. In high‐dimension low sample size (HDLSS) settings, this reduces the ‘dimension’ to that of the sample size. For HDLSS two‐class problems we modify Mika's kernel Fisher discriminant function which – in general – remains ill‐posed even in a kernel setting; see Mika et al. (1999). We propose a kernel naive Bayes discriminant function and its smoothed version, using first‐ and second‐degree polynomial kernels. For fixed sample size and increasing dimension, we present asymptotic expressions for the kernel discriminant functions, discriminant directions and for the error probability of our kernel discriminant functions. The theoretical calculations are complemented by simulations which show the convergence of the estimators to the population quantities as the dimension grows. We illustrate the performance of the new discriminant rules, which are easy to implement, on real HDLSS data. For such data, our results clearly demonstrate the superior performance of the new discriminant rules, and especially their smoothed versions, over Mika's kernel Fisher version, and typically also over the commonly used naive Bayes discriminant rule.