Testing Treatment-Covariate Interaction in a Nonparametric Analysis of Covariance Model

We consider a recently introduced nonparametric model for Analysis of Covariance and derive an asymptotic test for interaction between covariate and treatment. Furthermore, we suggest data depth techniques to obtain joint confidence regions for the covariate effects in this model.

The finite sample behavior of the asymptotic method is evaluated in simulations. Application of the procedures is illustrated using an epileptic seizures and chemotherapy data set.     

Ridge Estimation to the Restricted Linear Model

This article is concerned with the problem of multicollinearity in a linear model with linear restrictions. After introducing a spheral restricted condition, a new restricted ridge estimation method is proposed by minimizing the sum of squared residuals. The property of the new estimator in its superiority over the ordinary restricted least squares estimation is then theoretically analyzed. Furthermore, a sufficient and necessary condition for selecting the ridge parameter k is obtained. To simplify the selection of the ridge parameter, a sufficient condition is also given. Finally, a numerical example demonstrates the merit of the new method in the aspect of solving the multicollinearity over the ordinary restricted least squares estimation.     

Objective Bayesian Analysis of an Exponential Regression Model with Constrained Parameters Applied to Animal Digestibility

In animal digestibility the proportion of degraded food along the time has usually been modeled as a normal random variable with mean a function of the time and the following three parameters: the proportion of degraded food almost instantaneously, remaining proportion of food to be degraded, and velocity of degradation. The estimation of these parameters has been carried out mainly from a frequentist viewpoint by using the asymptotic distribution of the maximum likelihood estimator. This may give inadmissible estimates, such as values outside of the range of the parameters. This drawback could not appear if a Bayesian approach were adopted. In this article an objective Bayesian analysis is developed and illustrated on real and simulated data.     

Ridge Regression Estimation for Survey Samples

This paper describes procedure for constructing a vector of regression weights. Under the regression superpopulation model, the ridge regression estimator that has minimum model mean squared error is derived. Through a simulation study, we compare the ridge regression weights, regression weights, quadratic programming weights, and raking ratio weights. The ridge regression procedure with weights bounded by zero performed very well.     

Testing for the Equality of Two Autoregressive Functions Using Quasi-Residuals

This article discusses the problem of testing the equality of two nonparametric autoregressive functions against one-sided alternatives. The heteroscedastic errors and stationary densities of the two independent strong mixing strictly stationary time series can be possibly different. The article adapts the idea of using sum of quasi-residuals to construct the test and derives its asymptotic null distributions. The article also shows that the test is consistent for general alternatives and obtains its limiting distributions under a sequence of local alternatives. Then a Monte Carlo simulation is conducted to study the finite sample level and power behavior of these tests at some alternatives. We also compare the test to an existing lag matched test theoretically and by Monte Carlo experiments.     

Hypothesis Testing Problems in an Unbalanced Longitudinal Ophthalmology Study

ABSTRACT

The analysis of clustered data in a longitudinal ophthalmology study is complicated by correlations between repeatedly measured visual outcomes of paired eyes in a participant and missing observations due to the loss of follow-up. In the present article we consider hypothesis testing problems in an ophthalmology study, where eligible eyes are randomized to two treatments (when two eyes of a participant are eligible, the paired eyes are assigned to different treatments), and vision function outcomes are repeatedly measured over time. A large sample-based nonparametric test statistic and a nonparametric Bootstrap test analog are proposed for testing an interaction effect of two factors and testing an effect of a eye-specific factor within a level of the other person-specific factor on visual function outcomes. Both test statistics allow for missing observations, correlations between repeatedly measured outcomes on individual eyes, and correlations between repeatedly measured outcomes on both eyes of each participant. A simulation study shows that these proposed test statistics maintain nominal significance levels approximately and comparable powers to each other, as well as higher powers than the naive test statistic ignoring correlations between repeated bilateral measurements of both eyes in the same person. For illustration, we apply the proposed test statistics to the changes of visual field defect score in the Advanced Glaucoma Intervention Study.     

Nonparametric AMOC Changepoint Tests for Stochastically Ordered Alternatives

The problem considered is that of testing on the basis of a finite sequence of independent observations if all the observations have the same distribution versus the alternative that there is a unique change in the distribution and i.i.d. observations after the change are stochastically larger. The distributions before and after the possible change are continuous but not fully specified. We suggest a family of nonparametric tests based on ranks. Asymptotic approximations for the significance level of the test are obtained analytically. Monte Carlo experiments show that the rate of convergence of our asymptotics is fast.     

Combining Univariate Tests for Multivariate Location Problem

In this article, three methods of combining dependent univariate tests are studied. The Bahadur approximate efficiencies are derived under the asymptotic normal assumption. These procedures are applied to the multivariate location problem and compared with two Hotelling-type tests. A Monte Carlo study indicates that in certain cases the powers of the combination methods are much better than Hotelling's T ² and other multivariate nonparametric tests.     

Bayesian Estimation of the Regression Model with Autocorrelated Errors Under Contamination

In this article, the Bayesian analysis of the regression model with errors terms generated by a first-order autoregressive model is considered. Our aim is to study the effect of two kinds of contamination of this model via the posterior distribution of the regression parameter.