Estimation of Distribution Functions Using Data from Different Environments

Suppose that when a unit operatesin a certain environment, its lifetime has distribution G,and when the unit operates in another environment, its lifetimehas a different distribution, say F. Moreover, supposethe unit is operated for a certain period of time in the firstenvironment and is then transferred to the second environment.Thus we observe a censored lifetime in the first environmentand a failure time of a ``used' unit in the second environment.We propose an EM algorithm approach for obtaining a self-consistentestimator of F. Moreover, suppose using observations from both environments.The case where failure times are subject to right censoring isconsidered as well. We also establish the maximum likelihoodestimator of F. Moreover, suppose when the unit is repairable. Applicationand simulation studies are presented to illustrate the methodsderived.     

Estimating the propagation rate of a viral infection of potato plants via mixtures of regressions

A problem arising from the study of the spread of a viral infection among potato plants by aphids appears to involve a mixture of two linear regressions on a single predictor variable. The plant scientists studying the problem were particularly interested in obtaining a 95% confidence upper bound for the infection rate. We discuss briefly the procedure for fitting mixtures of regression models by means of maximum likelihood, effected via the EM algorithm. We give general expressions for the implementation of the M-step and then address the issue of conducting statistical inference in this context. A technique due to T. A. Louis may be used to estimate the covariance matrix of the parameter estimates by calculating the observed Fisher information matrix. We develop general expressions for the entries of this information matrix. Having the complete covariance matrix permits the calculation of confidence and prediction bands for the fitted model. We also investigate the testing of hypotheses concerning the number of components in the mixture via parametric and 'semiparametric' bootstrapping. Finally, we develop a method of producing diagnostic plots of the residuals from a mixture of linear regressions.     

Standard errors for EM estimation

The EM algorithm is a popular method for computing maximum likelihood estimates. One of its drawbacks is that it does not produce standard errors as a by-product. We consider obtaining standard errors by numerical differentiation. Two approaches are considered. The first differentiates the Fisher score vector to yield the Hessian of the log-likelihood. The second differentiates the EM operator and uses an identity that relates its derivative to the Hessian of the log-likelihood. The well-known SEM algorithm uses the second approach. We consider three additional algorithms: one that uses the first approach and two that use the second. We evaluate the complexity and precision of these three and the SEM in algorithm seven examples. The first is a single-parameter example used to give insight. The others are three examples in each of two areas of EM application: Poisson mixture models and the estimation of covariance from incomplete data. The examples show that there are algorithms that are much simpler and more accurate than the SEM algorithm. Hopefully their simplicity will increase the availability of standard error estimates in EM applications. It is shown that, as previously conjectured, a symmetry diagnostic can accurately estimate errors arising from numerical differentiation. Some issues related to the speed of the EM algorithm and algorithms that differentiate the EM operator are identified.     

Accelerated test system strength models based on Birnbaum–Saunders distribution: a complete Bayesian analysis and comparison

Several models for studies related to tensile strength of materials are proposed in the literature where the size or length component has been taken to be an important factor for studying the specimens’ failure behaviour. An important model, developed on the basis of cumulative damage approach, is the three-parameter extension of the Birnbaum–Saunders fatigue model that incorporates size of the specimen as an additional variable. This model is a strong competitor of the commonly used Weibull model and stands better than the traditional models, which do not incorporate the size effect. The paper considers two such cumulative damage models, checks their compatibility with a real dataset, compares them with some of the recent toolkits, and finally recommends a model, which appears an appropriate one. Throughout the study is Bayesian based on Markov chain Monte Carlo simulation.     

Estimation in capture–recapture models when covariates are subject to measurement errors and missing data

For capture–recapture models when covariates are subject to measurement errors and missing data, a set of estimating equations is constructed to estimate population size and relevant parameters. These estimating equations can be solved by an algorithm similar to the EM algorithm. The proposed method is also applicable to the situation when covariates with no measurement errors have missing data. Simulation studies are used to assess the performance of the proposed estimator. The estimator is also applied to a capture–recapture experiment on the bird species Prinia flaviventris in Hong Kong. The Canadian Journal of Statistics 37: 645–658; 2009 © 2009 Statistical Society of Canada     

Integrated methodology for multiple systems estimation and record linkage using a missing data formulation

There are now three essentially separate literatures on the topics of multiple systems estimation, record linkage, and missing data. But in practice the three are intimately intertwined. For example, record linkage involving multiple data sources for human populations is often carried out with the expressed goal of developing a merged database for multiple system estimation (MSE). Similarly, one way to view both the record linkage and MSE problems is as ones involving the estimation of missing data. This presentation highlights the technical nature of these interrelationships and provides a preliminary effort at their integration.     

Heterogeneous data modeling with two-component Weibull–Poisson distribution

The mixture distribution models are more useful than pure distributions in modeling of heterogeneous data sets. The aim of this paper is to propose mixture of Weibull–Poisson (WP) distributions to model heterogeneous data sets for the first time. So, a powerful alternative mixture distribution is created for modeling of the heterogeneous data sets. In the study, many features of the proposed mixture of WP distributions are examined. Also, the expectation maximization (EM) algorithm is used to determine the maximum-likelihood estimates of the parameters, and the simulation study is conducted for evaluating the performance of the proposed EM scheme. Applications for two real heterogeneous data sets are given to show the flexibility and potentiality of the new mixture distribution.     

Estimation under modified Weibull distribution based on right censored generalized order statistics

In this paper, the maximum likelihood (ML) and Bayes, by using Markov chain Monte Carlo (MCMC), methods are considered to estimate the parameters of three-parameter modified Weibull distribution (MWD(β, τ, λ)) based on a right censored sample of generalized order statistics (gos). Simulation experiments are conducted to demonstrate the efficiency of the proposed methods. Some comparisons are carried out between the ML and Bayes methods by computing the mean squared errors (MSEs), Akaike's information criteria (AIC) and Bayesian information criteria (BIC) of the estimates to illustrate the paper. Three real data sets from Weibull(α, β) distribution are introduced and analyzed using the MWD(β, τ, λ) and also using the Weibull(α, β) distribution. A comparison is carried out between the mentioned models based on the corresponding Kolmogorov–Smirnov (K–S) test statistic, {AIC and BIC} to emphasize that the MWD(β, τ, λ) fits the data better than the other distribution. All parameters are estimated based on type-II censored sample, censored upper record values and progressively type-II censored sample which are generated from the real data sets.     

Parameter estimation of nonlinear mixed-effects models using first-order conditional linearization and the EM algorithm

Nonlinear mixed-effects (NLME) models are flexible enough to handle repeated-measures data from various disciplines. In this article, we propose both maximum-likelihood and restricted maximum-likelihood estimations of NLME models using first-order conditional expansion (FOCE) and the expectation–maximization (EM) algorithm. The FOCE-EM algorithm implemented in the ForStat procedure SNLME is compared with the Lindstrom and Bates (LB) algorithm implemented in both the SAS macro NLINMIX and the S-Plus/R function nlme in terms of computational efficiency and statistical properties. Two realworld data sets an orange tree data set and a Chinese fir (Cunninghamia lanceolata) data set, and a simulated data set were used for evaluation. FOCE-EM converged for all mixed models derived from the base model in the two realworld cases, while LB did not, especially for the models in which random effects are simultaneously considered in several parameters to account for between-subject variation. However, both algorithms had identical estimated parameters and fit statistics for the converged models. We therefore recommend using FOCE-EM in NLME models, particularly when convergence is a concern in model selection.     

A time-varying measurement error model for age of onset of a psychiatric diagnosis: applied to first depressive episode diagnosed by the Composite International Diagnostic Interview (CIDI)

A substantial degree of uncertainty exists surrounding the reconstruction of events based on memory recall. This form of measurement error affects the performance of structured interviews such as the Composite International Diagnostic Interview (CIDI), an important tool to assess mental health in the community. Measurement error probably explains the discrepancy in estimates between longitudinal studies with repeated assessments (the gold-standard), yielding approximately constant rates of depression, versus cross-sectional studies which often find increasing rates closer in time to the interview. Repeated assessments of current status (or recent history) are more reliable than reconstruction of a person's psychiatric history based on a single interview. In this paper, we demonstrate a method of estimating a time-varying measurement error distribution in the age of onset of an initial depressive episode, as diagnosed by the CIDI, based on an assumption regarding age-specific incidence rates. High-dimensional non-parametric estimation is achieved by the EM-algorithm with smoothing. The method is applied to data from a Norwegian mental health survey in 2000. The measurement error distribution changes dramatically from 1980 to 2000, with increasing variance and greater bias further away in time from the interview. Some influence of the measurement error on already published results is found.