双重合约论————基于对外部性的新解释

外部性的新定义是：没有参与订立特定相关合约的其他人所给予上述合约订立人的影响。上述订立的特定相关合约就是内部合约。所谓影响或某种控制,都是经过一致同意达成合约实现的。上述“其他人”不参加内部合约从而不受它控制,但对内部合约订立人产生影响,必定是同内部合约订立人达成了另外的合约即外部合约。上述内外合约组合成双重合约,这是一个普遍存在的事实。在拥有完全退出权的条件下,所有合约包括内外合约,都是每个参与人通过收益成本计算而一致同意达成的,其中包括为降低决策成本而一致同意采取各种授权方式达成的合约。内外合约的联系即相互之间的影响是双向的,其中外部合约作为外部选择点,由于条件的不同,或是可以保障内部合约的达成与稳定,或是可以替代内部合约参与人使其退出并改变内部合约。但上述退出权的实现取决于退出效用是否不小于退出成本。公共选择、合作博弈、讨价还价和一般均衡等理论同样可以解释双重合约。     

Fitting competing risks data to bivariate Pareto models

This paper revisits two bivariate Pareto models for fitting competing risks data. The first model is the Frank copula model, and the second one is a bivariate Pareto model introduced by Sankaran and Nair (1993 Sankaran, P. G., and N. U. Nair. 1993. A bivariate Pareto model and its applications to reliability. Naval Research Logistics 40 (7):1013–1020. doi:10.1002/1520-6750(199312)40:7%3c1013::AID-NAV3220400711%3e3.0.CO;2-7.[Crossref], [Web of Science ®] , [Google Scholar]). We discuss the identifiability issues of these models and develop the maximum likelihood estimation procedures including their computational algorithms and model-diagnostic procedures. Simulations are conducted to examine the performance of the maximum likelihood estimation. Real data are analyzed for illustration.     

A New Quantile Function with Applications to Reliability Analysis

In this article, we propose a new class of distributions defined by a quantile function, which nests several distributions as its members. The quantile function proposed here is the sum of the quantile functions of the generalized Pareto and Weibull distributions. Various distributional properties and reliability characteristics of the class are discussed. The estimation of the parameters of the model using L-moments is studied. Finally, we apply the model to a real life dataset.     

Construction of bivariate and multivariate weighted distributions via conditioning

Weighted distributions (univariate and bivariate) have received widespread attention over the last two decades because of their flexibility for analyzing skewed data. In this article, we propose an alternative method to construct a new family of bivariate and multivariate weighted distributions. For illustrative purposes, some examples of the proposed method are presented. Several structural properties of the bivariate weighted distributions including marginal distributions together with distributions of the minimum and maximum, evaluation of the reliability parameter, and verification of total positivity of order two are also presented. In addition, we provide some multivariate extensions of the proposed models. A real-life data set is used to show the applicability of these bivariate weighted distributions.     

A comparison of L-, LQ-, TL-moment and maximum likelihood high quantile estimates of the GPD and GEV distribution

In this article, L-moments, LQ-moments and TL-moments of the generalized Pareto and generalized extreme-value distributions are derived up to the fourth order. The first three L-, LQ- and TL-moments are used to obtain estimators of their parameters. Performing a simulation study, high-quantile estimates based on L-, LQ-, and TL-moments are compared to the maximum likelihood estimate with respect to their sample mean squared error. This consists of identifying an optimal combination of parameters α and p both considered in the range [0, 0.5] for estimating quantiles by LQ-moments. The results show L-moment and maximum likelihood methods outperform other methods.     

Bayesian prediction of order statistics with fixed and random sample sizes based on k-record values from Pareto distribution

In this paper, the two-parameter Pareto distribution is considered and the problem of prediction of order statistics from a future sample and that of its geometric mean are discussed. The Bayesian approach is applied to construct predictors based on observed k-record values for the cases when the future sample size is fixed and when it is random. Several Bayesian prediction intervals are derived. Finally, the results of a simulation study and a numerical example are presented for illustrating all the inferential procedures developed here.     

Continuously Representable Paretian Quasi-Orders

Two forms of continuity are defined for Pareto representations of preferences. They are designated “continuity” and “coordinate continuity.” Characterizations are given of those Pareto representable preferences that are continuously representable and, in dimension two, of those that are coordinate-continuously representable.     

A Quality Risk Management Model Approach for Cell Therapy Manufacturing

International regulatory authorities view risk management as an essential production need for the development of innovative, somatic cell‐based therapies in regenerative medicine. The available risk management guidelines, however, provide little guidance on specific risk analysis approaches and procedures applicable in clinical cell therapy manufacturing. This raises a number of problems. Cell manufacturing is a poorly automated process, prone to operator‐introduced variations, and affected by heterogeneity of the processed organs/tissues and lot‐dependent variability of reagent (e.g., collagenase) efficiency. In this study, the principal challenges faced in a cell‐based product manufacturing context (i.e., high dependence on human intervention and absence of reference standards for acceptable risk levels) are identified and addressed, and a risk management model approach applicable to manufacturing of cells for clinical use is described for the first time. The use of the heuristic and pseudo‐quantitative failure mode and effect analysis/failure mode and critical effect analysis risk analysis technique associated with direct estimation of severity, occurrence, and detection is, in this specific context, as effective as, but more efficient than, the analytic hierarchy process. Moreover, a severity/occurrence matrix and Pareto analysis can be successfully adopted to identify priority failure modes on which to act to mitigate risks. The application of this approach to clinical cell therapy manufacturing in regenerative medicine is also discussed.     

考虑时效与公平性的震后应急物资动态配送优化研究

大规模地震后应急物资的高效保障是应急救援有效开展的必要前提。震后应急物资运输与配送包括从区域储备仓库和外围物资集散地运输到区域应急配送中心、由区域应急配送中心配送到各个受灾点两个阶段。应急物资保障具有持续时间长、需求紧迫性强和物资相对短缺等特点。本文以应急物资保障时效性与分配公平性为目标,建立了考虑多种运输方式、多时段动态的应急物资配送中心选址与运输配送路径优化的多目标规划模型,并基于此模型设计了一种带精英策略的非支配排序的遗传算法,以九寨沟地区地震灾难情景对模型进行实证研究,验证了模型和算法的有效性,以期为震后应急物资保障提供理论指导与决策支持。     

Risks of Mortality and Morbidity from Worldwide Terrorism: 1968–2004

Worldwide data on terrorist incidents between 1968 and 2004 gathered by the RAND Corporation and the Oklahoma City National Memorial Institute for the Prevention of Terrorism (MIPT) were assessed for patterns and trends in morbidity/mortality. Adjusted data analyzed involve a total of 19,828 events, 7,401 "adverse" events (each causing >or= 1 victim), and 86,568 "casualties" (injuries), of which 25,408 were fatal. Most terror-related adverse events, casualties, and deaths involved bombs and guns. Weapon-specific patterns and terror-related risk levels in Israel (IS) have differed markedly from those of all other regions combined (OR). IS had a fatal fraction of casualties about half that of OR, but has experienced relatively constant lifetime terror-related casualty risks on the order of 0.5%--a level 2 to 3 orders of magnitude more than those experienced in OR that increased approximately 100-fold over the same period. Individual event fatality has increased steadily, the median increasing from 14% to 50%. Lorenz curves obtained indicate substantial dispersion among victim/event rates: about half of all victims were caused by the top 2.5% (or 10%) of harm-ranked events in OR (or IS). Extreme values of victim/event rates were approximated fairly well by generalized Pareto models (typically used to fit to data on forest fires, sea levels, earthquakes, etc.). These results were in turn used to forecast maximum OR- and IS-specific victims/event rates through 2080, illustrating empirically-based methods that could be applied to improve strategies to assess, prevent, and manage terror-related risks and consequences.