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41.
Incorporation of historical controls using semiparametric mixed models   总被引:1,自引:0,他引:1  
The analysis of animal carcinogenicity data is complicated by various statistical issues. A topic of recent debate is how to control for the effect of the animal's body weight on the outcome of interest, the onset of tumours. We propose a method which incorporates historical information from the control animals in previously conducted experiments. We allow non-linearity in the effects of body weight by modelling the relationship nonparametrically through a penalized spline. A simple extension of the penalized spline model allows the relationship between weight and the onset of tumour to vary from one experiment to another.  相似文献   
42.
Summary.  The fundamental equations that model turbulent flow do not provide much insight into the size and shape of observed turbulent structures. We investigate the efficient and accurate representation of structures in two-dimensional turbulence by applying statistical models directly to the simulated vorticity field. Rather than extract the coherent portion of the image from the background variation, as in the classical signal-plus-noise model, we present a model for individual vortices using the non-decimated discrete wavelet transform. A template image, which is supplied by the user, provides the features to be extracted from the vorticity field. By transforming the vortex template into the wavelet domain, specific characteristics that are present in the template, such as size and symmetry, are broken down into components that are associated with spatial frequencies. Multivariate multiple linear regression is used to fit the vortex template to the vorticity field in the wavelet domain. Since all levels of the template decomposition may be used to model each level in the field decomposition, the resulting model need not be identical to the template. Application to a vortex census algorithm that records quantities of interest (such as size, peak amplitude and circulation) as the vorticity field evolves is given. The multiresolution census algorithm extracts coherent structures of all shapes and sizes in simulated vorticity fields and can reproduce known physical scaling laws when processing a set of vorticity fields that evolve over time.  相似文献   
43.
Summary.  On-line auctions pose many challenges for the empirical researcher, one of which is the effective and reliable modelling of price paths. We propose a novel way of modelling price paths in eBay's on-line auctions by using functional data analysis. One of the practical challenges is that the functional objects are sampled only very sparsely and unevenly. Most approaches rely on smoothing to recover the underlying functional object from the data, which can be difficult if the data are irregularly distributed. We present a new approach that can overcome this challenge. The approach is based on the ideas of mixed models. Specifically, we propose a semiparametric mixed model with boosting to recover the functional object. As well as being able to handle sparse and unevenly distributed data, the model also results in conceptually more meaningful functional objects. In particular, we motivate our method within the framework of eBay's on-line auctions. On-line auctions produce monotonic increasing price curves that are often correlated across auctions. The semiparametric mixed model accounts for this correlation in a parsimonious way. It also manages to capture the underlying monotonic trend in the data without imposing model constraints. Our application shows that the resulting functional objects are conceptually more appealing. Moreover, when used to forecast the outcome of an on-line auction, our approach also results in more accurate price predictions compared with standard approaches. We illustrate our model on a set of 183 closed auctions for Palm M515 personal digital assistants.  相似文献   
44.
在评价制造业绩效时,环境因素是一个要考虑的影响因子。基于方向性环境距离函数,选取陕西省不同要素密集行业2005—2011年数据,比较了考虑环境因素和不考虑环境因素两种情形下的陕西省制造业绩效。研究发现,考虑CO2排放后制造业在生产前沿上的行业数目减少,陕西省制造业的整体绩效不高且规模收益总体上呈递减趋势;技术密集型制造业的平均绩效最高,主要是技术进步较快所致,劳动密集型行业绩效主要依赖规模效率变化的推动,而资本密集型行业绩效的"追赶效应"最为明显;大多数劳动、资本密集型行业表现出技术退步趋势,"前沿面移动效应"不明显,企业管理水平不高,投入结构有待优化,技术进步缓慢。针对研究结果最后提出了相应的对策建议。  相似文献   
45.
The INAR(1) model (integer-valued autoregressive) is commonly used to model serially dependent processes of Poisson counts. We propose several asymptotic simultaneous confidence regions for the two parameters of a Poisson INAR(1) model, and investigate their performance and robustness for finite-length time series in a simulation study. Practical recommendations are derived, and the application of the confidence regions is illustrated by a real-data example.  相似文献   
46.
While there has been considerable research on the analysis of extreme values and outliers by using heavy-tailed distributions, little is known about the semi-heavy-tailed behaviors of data when there are a few suspicious outliers. To address the situation where data are skewed possessing semi-heavy tails, we introduce two new skewed distribution families of the hyperbolic secant with exciting properties. We extend the semi-heavy-tailedness property of data to a linear regression model. In particular, we investigate the asymptotic properties of the ML estimators of the regression parameters when the error term has a semi-heavy-tailed distribution. We conduct simulation studies comparing the ML estimators of the regression parameters under various assumptions for the distribution of the error term. We also provide three real examples to show the priority of the semi-heavy-tailedness of the error term comparing to heavy-tailedness. Online supplementary materials for this article are available. All the new proposed models in this work are implemented by the shs R package, which can be found on the GitHub webpage.  相似文献   
47.
We propose penalized-likelihood methods for parameter estimation of high dimensional t distribution. First, we show that a general class of commonly used shrinkage covariance matrix estimators for multivariate normal can be obtained as penalized-likelihood estimator with a penalty that is proportional to the entropy loss between the estimate and an appropriately chosen shrinkage target. Motivated by this fact, we then consider applying this penalty to multivariate t distribution. The penalized estimate can be computed efficiently using EM algorithm for given tuning parameters. It can also be viewed as an empirical Bayes estimator. Taking advantage of its Bayesian interpretation, we propose a variant of the method of moments to effectively elicit the tuning parameters. Simulations and real data analysis demonstrate the competitive performance of the new methods.  相似文献   
48.
 本文讨论了指数族广义部分线性单指数模型(Generalized Partially Linear Single Index Models, GPLSIM) 的惩罚样条迭代估计,提出了基于惩罚似然和一组预先取定的单指数参数向量 的初始估计的迭代估计算法。另外本文还通过一组模拟数据的分析对所提出的迭代算法进行了验证。  相似文献   
49.
A general formulation of mixed proportional hazard models with K random effects is provided. It enables to account for a population stratified at K different levels. I then show how to approximate the partial maximum likelihood estimator using an EM algorithm. In a Monte Carlo study, the behavior of the estimator is assessed and I provide an application to the ratification of ILO conventions. Compared to other procedures, the results indicate an important decrease in computing time, as well as improved convergence and stability.  相似文献   
50.
In this paper, we propose a lower bound based smoothed quasi-Newton algorithm for computing the solution paths of the group bridge estimator in linear regression models. Our method is based on the quasi-Newton algorithm with a smoothed group bridge penalty in combination with a novel data-driven thresholding rule for the regression coefficients. This rule is derived based on a necessary KKT condition of the group bridge optimization problem. It is easy to implement and can be used to eliminate groups with zero coefficients. Thus, it reduces the dimension of the optimization problem. The proposed algorithm removes the restriction of groupwise orthogonal condition needed in coordinate descent and LARS algorithms for group variable selection. Numerical results show that the proposed algorithm outperforms the coordinate descent based algorithms in both efficiency and accuracy.  相似文献   
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