A Bayesian method of sample size determination with practical applications

Summary.  The problem motivating the paper is the determination of sample size in clinical trials under normal likelihoods and at the substantive testing stage of a financial audit where normality is not an appropriate assumption. A combination of analytical and simulation-based techniques within the Bayesian framework is proposed. The framework accommodates two different prior distributions: one is the general purpose fitting prior distribution that is used in Bayesian analysis and the other is the expert subjective prior distribution, the sampling prior which is believed to generate the parameter values which in turn generate the data. We obtain many theoretical results and one key result is that typical non-informative prior distributions lead to very small sample sizes. In contrast, a very informative prior distribution may either lead to a very small or a very large sample size depending on the location of the centre of the prior distribution and the hypothesized value of the parameter. The methods that are developed are quite general and can be applied to other sample size determination problems. Some numerical illustrations which bring out many other aspects of the optimum sample size are given.     

Doubly periodic non-homogeneous Poisson models for hurricane data

Non-homogeneous Poisson processes with periodic claim intensity rate have been proposed as claim counts in risk theory. Here a doubly periodic Poisson model with short- and long-term trends is studied. Beta-type intensity functions are presented as illustrations. The likelihood function and the maximum likelihood estimates of the model parameters are derived.Doubly periodic Poisson models are appropriate when the seasonality does not repeat exactly the same short-term pattern every year, but has a peak intensity that varies over a longer period. This reflects periodic environments like those forming hurricanes, in alternating El Niño/La Niña years. An application of the model to the data set of Atlantic hurricanes affecting the United States (1899–2000) is discussed in detail.     

INFERENCE ABOUT THE MEAN OF A POISSON DISTRIBUTION IN THE PRESENCE OF A NUISANCE PARAMETER

In this note we examine the problem of estimating the mean of a Poisson distribution when a nuisance parameter is present. Using a condition of Cox (1958) about ancillarity in the presence of a nuisance parameter, we justify that inference about the parameter should be carried out using the conditional distribution given the appropriate ancillary statistics. A small simulation study has been done to compare the performance of the conditional likelihood approach and the standard likelihood approach.     

ON THE GENERALIZED RAO-RUBIN CONDITION and SOME VARIANTS

This paper gives a characterization of some members of the compound Poisson family of distributions based on the generalized Rao-Rubin condition. By considering some variants of this condition and using power series arguments, characterizations of the Poisson distribution are also obtained.     

On uniform approximation of Poisson variates by normal ones

In this paper the accuracy of the normal approximation to the Poisson is treated from the viewpoint of direct approximation of Poisson variables by normal ones. The conclusions that are derived on the accuracy of this approximation lead (among others) to very useful results on confidence limits for the mean of a linear combination of independent Poisson variables; these latter are employed in precise determination of the composition of a mixture of radioactive isotopes by means of a scintillation counter.     

A Bayesian model for ranking hazardous road sites

Summary.  Road safety has recently become a major concern in most modern societies. The identification of sites that are more dangerous than others (black spots) can help in better scheduling road safety policies. This paper proposes a methodology for ranking sites according to their level of hazard. The model is innovative in at least two respects. Firstly, it makes use of all relevant information per accident location, including the total number of accidents and the number of fatalities, as well as the number of slight and serious injuries. Secondly, the model includes the use of a cost function to rank the sites with respect to their total expected cost to society. Bayesian estimation for the model via a Markov chain Monte Carlo approach is proposed. Accident data from 519 intersections in Leuven (Belgium) are used to illustrate the methodology proposed. Furthermore, different cost functions are used to show the effect of the proposed method on the use of different costs per type of injury.     

A method of deriving valid approximate expressions for bias in ratio estimation

The expectation of a ratio of two statistics is usually obtained by the method in which the denominator is expanded into a binomial series around its mean. However, this method can less generally be employed because the expansion of the denominator is not always valid. This paper presents a device in which the expectation of a ratio of two statistics can more generally be obtained. The device is to adopt a positive value as ‘catalyzer’. It can be applied not only to the ratio of estimates based on samples but also to ratio of any two statistics, if the denominator is positive and finite.