State transition modeling of complex monitored health data

This article considers the analysis of complex monitored health data, where often one or several signals are reflecting the current health status that can be represented by a finite number of states, in addition to a set of covariates. In particular, we consider a novel application of a non-parametric state intensity regression method in order to study time-dependent effects of covariates on the state transition intensities. The method can handle baseline, time varying as well as dynamic covariates. Because of the non-parametric nature, the method can handle different data types and challenges under minimal assumptions. If the signal that is reflecting the current health status is of continuous nature, we propose the application of a weighted median and a hysteresis filter as data pre-processing steps in order to facilitate robust analysis. In intensity regression, covariates can be aggregated by a suitable functional form over a time history window. We propose to study the estimated cumulative regression parameters for different choices of the time history window in order to investigate short- and long-term effects of the given covariates. The proposed framework is discussed and applied to resuscitation data of newborns collected in Tanzania.     

Statistical inference based on generalized Lindley record values

This paper addresses the problems of frequentist and Bayesian estimation for the unknown parameters of generalized Lindley distribution based on lower record values. We first derive the exact explicit expressions for the single and product moments of lower record values, and then use these results to compute the means, variances and covariance between two lower record values. We next obtain the maximum likelihood estimators and associated asymptotic confidence intervals. Furthermore, we obtain Bayes estimators under the assumption of gamma priors on both the shape and the scale parameters of the generalized Lindley distribution, and associated the highest posterior density interval estimates. The Bayesian estimation is studied with respect to both symmetric (squared error) and asymmetric (linear-exponential (LINEX)) loss functions. Finally, we compute Bayesian predictive estimates and predictive interval estimates for the future record values. To illustrate the findings, one real data set is analyzed, and Monte Carlo simulations are performed to compare the performances of the proposed methods of estimation and prediction.     

Improved two-parameter estimators for the negative binomial and Poisson regression models

Negative binomial regression (NBR) and Poisson regression (PR) applications have become very popular in the analysis of count data in recent years. However, if there is a high degree of relationship between the independent variables, the problem of multicollinearity arises in these models. We introduce new two-parameter estimators (TPEs) for the NBR and the PR models by unifying the two-parameter estimator (TPE) of Özkale and Kaç?ranlar [The restricted and unrestricted two-parameter estimators. Commun Stat Theory Methods. 2007;36:2707–2725]. These new estimators are general estimators which include maximum likelihood (ML) estimator, ridge estimator (RE), Liu estimator (LE) and contraction estimator (CE) as special cases. Furthermore, biasing parameters of these estimators are given and a Monte Carlo simulation is done to evaluate the performance of these estimators using mean square error (MSE) criterion. The benefits of the new TPEs are also illustrated in an empirical application. The results show that the new proposed TPEs for the NBR and the PR models are better than the ML estimator, the RE and the LE.     

Generalized estimator of population mean by using conventional and non-conventional measures in the presence of measurement errors

In survey research, it is assumed that reported response by the individual is correct. However, given the issues of prestige bias, self-respect, respondent's reported data often produces estimated values which are highly deviated from the true values. This causes measurement error (ME) to be present in the sample estimates. In this article, the estimation of population mean in the presence of measurement error using information on a single auxiliary variable is studied. A generalized estimator of population mean is proposed. The class of estimators is obtained by using some conventional and non-conventional measures. Simulation and numerical study is also conducted to assess the performance of estimators in the presence and absence of measurement error.     

Double robust estimator in general treatment regimes based on Covariate-balancing

Double robust estimators have double the chance of being a consistent estimator of a causal effect in binary treatments cases. In this paper, we proposed an estimator of a causal effect for general treatment regimes based on covariate-balancing. Under parametrical situation, our estimator has double robustness.     

Confidence intervals based on the deviance statistic for the hyperparameters in state space models

The main objective of this work is to evaluate the performance of confidence intervals, built using the deviance statistic, for the hyperparameters of state space models. The first procedure is a marginal approximation to confidence regions, based on the likelihood test, and the second one is based on the signed root deviance profile. Those methods are computationally efficient and are not affected by problems such as intervals with limits outside the parameter space, which can be the case when the focus is on the variances of the errors. The procedures are compared to the usual approaches existing in the literature, which includes the method based on the asymptotic distribution of the maximum likelihood estimator, as well as bootstrap confidence intervals. The comparison is performed via a Monte Carlo study, in order to establish empirically the advantages and disadvantages of each method. The results show that the methods based on the deviance statistic possess a better coverage rate than the asymptotic and bootstrap procedures.     

MSE performance of the weighted average estimators consisting of shrinkage estimators when each individual regression coefficient is estimated

In this paper, we analytically derive the exact formula for the mean squared error (MSE) of two weighted average (WA) estimators for each individual regression coefficient. Further, we execute numerical evaluations to investigate small sample properties of the WA estimators, and compare the MSE performance of the WA estimators with the other shrinkage estimators and the usual OLS estimator. Our numerical results show that (1) the WA estimators have smaller MSE than the other shrinkage estimators and the OLS estimator over a wide region of parameter space; (2) the range where the relative MSE of the WA estimator is smaller than that of the OLS estimator gets narrower as the number of explanatory variables k increases.     

贫困脆弱性视角下参与式社区综合发展的精准“防贫”效应分析

利用贵州省纳雍县两个贫困行政村跨期十数年的农户追踪调查数据,从贫困脆弱性视角量化分析、评价不同时期参与式社区综合发展的“防贫”效应及其精准性。结果表明,欠发达地区农户的贫困脆弱性在1999-2011年期间降幅巨大（约下降99%）,抗风险冲击能力得到极大提升。总体上,参与式社区综合发展的“防贫”即期效应显著,可使农户贫困脆弱性指数降低5个百分点以上,然其“防贫”时滞效应却并不突出。分不同群体考察,参与式社区综合发展“防贫”虽存在一定“漏出效应”和“溢出效应”,但包容性较强、瞄准精度尚可,能惠及大多数“重度脆弱户”和“中度、轻度脆弱户”;换言之,除“微度脆弱户”、“极度脆弱户”及部分“重度脆弱户”外,其间各贫困脆弱组农户均能从中得到保障,然贫困脆弱性强度越高,所受保障程度愈小。不仅如此,参与式社区综合发展此种“防贫”的精准度可持续性差,无明显时滞效应。     

ESTIMATING A PARAMETER WHEN IT IS KNOWN THAT THE PARAMETER EXCEEDS A GIVEN VALUE

In some statistical problems a degree of explicit, prior information is available about the value taken by the parameter of interest, θ say, although the information is much less than would be needed to place a prior density on the parameter's distribution. Often the prior information takes the form of a simple bound, ‘θ > θ₁ ’ or ‘θ < θ₁ ’, where θ₁ is determined by physical considerations or mathematical theory, such as positivity of a variance. A conventional approach to accommodating the requirement that θ > θ₁ is to replace an estimator, , of θ by the maximum of and θ₁. However, this technique is generally inadequate. For one thing, it does not respect the strictness of the inequality θ > θ₁ , which can be critical in interpreting results. For another, it produces an estimator that does not respond in a natural way to perturbations of the data. In this paper we suggest an alternative approach, in which bootstrap aggregation, or bagging, is used to overcome these difficulties. Bagging gives estimators that, when subjected to the constraint θ > θ₁ , strictly exceed θ₁ except in extreme settings in which the empirical evidence strongly contradicts the constraint. Bagging also reduces estimator variability in the important case for which is close to θ₁, and more generally produces estimators that respect the constraint in a smooth, realistic fashion.     

Another look at Huber's estimator: A new minimax estimator in regression with stochastically bounded noise

Huber's estimator has had a long lasting impact, particularly on robust statistics. It is well known that under certain conditions, Huber's estimator is asymptotically minimax. A moderate generalization in rederiving Huber's estimator shows that Huber's estimator is not the only choice. We develop an alternative asymptotic minimax estimator and name it regression with stochastically bounded noise (RSBN). Simulations demonstrate that RSBN is slightly better in performance, although it is unclear how to justify such an improvement theoretically. We propose two numerical solutions: an iterative numerical solution, which is extremely easy to implement and is based on the proximal point method; and a solution by applying state-of-the-art nonlinear optimization software packages, e.g., SNOPT. Contribution: the generalization of the variational approach is interesting and should be useful in deriving other asymptotic minimax estimators in other problems.