全文获取类型
收费全文 | 5690篇 |
免费 | 190篇 |
国内免费 | 55篇 |
专业分类
管理学 | 428篇 |
民族学 | 14篇 |
人才学 | 6篇 |
人口学 | 42篇 |
丛书文集 | 358篇 |
理论方法论 | 63篇 |
综合类 | 3147篇 |
社会学 | 226篇 |
统计学 | 1651篇 |
出版年
2024年 | 8篇 |
2023年 | 43篇 |
2022年 | 17篇 |
2021年 | 60篇 |
2020年 | 80篇 |
2019年 | 100篇 |
2018年 | 136篇 |
2017年 | 186篇 |
2016年 | 113篇 |
2015年 | 164篇 |
2014年 | 265篇 |
2013年 | 837篇 |
2012年 | 379篇 |
2011年 | 391篇 |
2010年 | 308篇 |
2009年 | 322篇 |
2008年 | 329篇 |
2007年 | 330篇 |
2006年 | 291篇 |
2005年 | 294篇 |
2004年 | 222篇 |
2003年 | 229篇 |
2002年 | 205篇 |
2001年 | 164篇 |
2000年 | 114篇 |
1999年 | 61篇 |
1998年 | 40篇 |
1997年 | 36篇 |
1996年 | 25篇 |
1995年 | 19篇 |
1994年 | 22篇 |
1993年 | 13篇 |
1992年 | 16篇 |
1991年 | 10篇 |
1990年 | 8篇 |
1989年 | 10篇 |
1988年 | 5篇 |
1987年 | 11篇 |
1986年 | 3篇 |
1985年 | 15篇 |
1984年 | 20篇 |
1983年 | 7篇 |
1982年 | 11篇 |
1981年 | 5篇 |
1980年 | 2篇 |
1979年 | 4篇 |
1978年 | 1篇 |
1977年 | 4篇 |
排序方式: 共有5935条查询结果,搜索用时 750 毫秒
841.
Remove unwanted variation (RUV) is an estimation and normalization system in which the underlying correlation structure of a multivariate dataset is estimated from negative control measurements, typically gene expression values, which are assumed to stay constant across experimental conditions. In this paper we derive the weight matrix which is estimated and incorporated into the generalized least squares estimates of RUV-inverse, and show that this weight matrix estimates the average covariance matrix across negative control measurements. RUV-inverse can thus be viewed as an estimation method adjusting for an unknown experimental design. We show that for a balanced incomplete block design (BIBD), RUV-inverse recovers intra- and interblock estimates of the relevant parameters and combines them as a weighted sum just like the best linear unbiased estimator (BLUE), except that the weights are globally estimated from the negative control measurements instead of being individually optimized to each measurement as in the classical, single measurement BIBD BLUE. 相似文献
842.
The intention of this article is to highlight sources of web-based reference material and software that will aid consulting statisticians when designing clinical trials. The article includes websites that provide links to explanation of statistical concepts for non-statisticians, regulatory guidelines, and free statistical study design software. 相似文献
843.
Designs for early phase dose finding clinical trials typically are either phase I based on toxicity, or phase I-II based on toxicity and efficacy. These designs rely on the implicit assumption that the dose of an experimental agent chosen using these short-term outcomes will maximize the agent's long-term therapeutic success rate. In many clinical settings, this assumption is not true. A dose selected in an early phase oncology trial may give suboptimal progression-free survival or overall survival time, often due to a high rate of relapse following response. To address this problem, a new family of Bayesian generalized phase I-II designs is proposed. First, a conventional phase I-II design based on short-term outcomes is used to identify a set of candidate doses, rather than selecting one dose. Additional patients then are randomized among the candidates, patients are followed for a predefined longer time period, and a final dose is selected to maximize the long-term therapeutic success rate, defined in terms of duration of response. Dose-specific sample sizes in the randomization are determined adaptively to obtain a desired level of selection reliability. The design was motivated by a phase I-II trial to find an optimal dose of natural killer cells as targeted immunotherapy for recurrent or treatment-resistant B-cell hematologic malignancies. A simulation study shows that, under a range of scenarios in the context of this trial, the proposed design has much better performance than two conventional phase I-II designs. 相似文献
844.
Abstarct. This paper is concerned with studying the dependence structure between two random variables Y 1 and Y 2 conditionally upon a covariate X. The dependence structure is modelled via a copula function, which depends on the given value of the covariate in a general way. Gijbels et al. (Comput. Statist. Data Anal., 55, 2011, 1919) suggested two non‐parametric estimators of the ‘conditional’ copula and investigated their numerical performances. In this paper we establish the asymptotic properties of the proposed estimators as well as conditional association measures derived from them. Practical recommendations for their use are then discussed. 相似文献
845.
Tommaso Proietti Alessandra Luati 《Journal of statistical planning and inference》2011,141(2):831-845
The paper concerns the design of nonparametric low-pass filters that have the property of reproducing a polynomial of a given degree. Two approaches are considered. The first is locally weighted polynomial regression (LWPR), which leads to linear filters depending on three parameters: the bandwidth, the order of the fitting polynomial, and the kernel. We find a remarkable linear (hyperbolic) relationship between the cut-off period (frequency) and the bandwidth, conditional on the choices of the order and the kernel, upon which we build the design of a low-pass filter.The second hinges on a generalization of the maximum concentration approach, leading to filters related to discrete prolate spheroidal sequences (DPSS). In particular, we propose a new class of low-pass filters that maximize the concentration over a specified frequency range, subject to polynomial reproducing constraints. The design of generalized DPSS filters depends on three parameters: the bandwidth, the polynomial order, and the concentration frequency. We discuss the properties of the corresponding filters in relation to the LWPR filters, and illustrate their use for the design of low-pass filters by investigating how the three parameters are related to the cut-off frequency. 相似文献
846.
In many toxicological assays, interactions between primary and secondary effects may cause a downturn in mean responses at high doses. In this situation, the typical monotonicity assumption is invalid and may be quite misleading. Prior literature addresses the analysis of response functions with a downturn, but so far as we know, this paper initiates the study of experimental design for this situation. A growth model is combined with a death model to allow for the downturn in mean doses. Several different objective functions are studied. When the number of treatments equals the number of parameters, Fisher information is found to be independent of the model of the treatment means and on the magnitudes of the treatments. In general, A- and DA-optimal weights for estimating adjacent mean differences are found analytically for a simple model and numerically for a biologically motivated model. Results on c-optimality are also obtained for estimating the peak dose and the EC50 (the treatment with response half way between the control and the peak response on the increasing portion of the response function). Finally, when interest lies only in the increasing portion of the response function, we propose composite D-optimal designs. 相似文献
847.
Yang LiuJian-Feng Yang Min-Qian Liu 《Journal of statistical planning and inference》2011,141(9):3055-3062
Two fractional factorial designs are considered isomorphic if one can be obtained from the other by relabeling the factors, reordering the runs, and/or switching the levels of factors. To identify the isomorphism of two designs is known as an NP hard problem. In this paper, we propose a three-dimensional matrix named the letter interaction pattern matrix (LIPM) to characterize the information contained in the defining contrast subgroup of a regular two-level design. We first show that an LIPM could uniquely determine a design under isomorphism and then propose a set of principles to rearrange an LIPM to a standard form. In this way, we can significantly reduce the computational complexity in isomorphism check, which could only take O(2p)+O(3k3)+O(2k) operations to check two 2k−p designs in the worst case. We also find a sufficient condition for two designs being isomorphic to each other, which is very simple and easy to use. In the end, we list some designs with the maximum numbers of clear or strongly clear two-factor interactions which were not found before. 相似文献
848.
Rong-Xian Yue Hong QinKashinath Chatterjee 《Journal of statistical planning and inference》2011,141(7):2472-2479
This paper presents an extension of the work of Yue and Chatterjee (2010) about U-type designs for Bayesian nonparametric response prediction. We consider nonparametric Bayesian regression model with p responses. We use U-type designs with n runs, m factors and q levels for the nonparametric multiresponse prediction based on the asymptotic Bayesian criterion. A lower bound for the proposed criterion is established, and some optimal and nearly optimal designs for the illustrative models are given. 相似文献
849.
内容提要:本文应用聚类分析方法和Beta回归模型对2009年度交强险审计报告所披露的交强险经营数据进行了分析。结果表明,交强险在31个地区的赔付率差异显著,主要影响因素包括人均收入水平、物价指数、人均交通支出和人均车辆数。交强险9个业务类别之间的赔付率差异也很明显,表明现行保费水平存在严重的不公平。各地区的赔付率和费用率之间存在反常的负向相关关系,反映了交强险在费用分摊中存在某种不合理现象。保险公司的经营费用率在不同地区之间和不同业务类别之间都没有显著差异,主要受保险公司业务规模的影响,规模经济效应显著。 相似文献
850.
本文以国家数据为准,通过采用2005-2009年的数据为样本,从理论与实证上比较分析了地区与国家GDP数据衔接的三种方法即Geary和Stark的产出估算方法、线性调整法与辅助回归法,比较结果显示:(1)从理论上分析,三种方法都有其合理性,只是辅助回归法较另两种方法更具可取性。(2)从衔接效果上看,辅助回归法优于Geary和Stark的产出估算方法,Geary和Stark的产出估算方法又优于线性调整法。不过不同的方法皆有相应的适用场合与特点以及不同的衔接效果,因而只能说三种方法中有趋优的方法,但不能明确断定何种方法可以具体应用于实际数据衔接中并能达到良好的调整效果。 相似文献