Comment on “Exact Bayesian variable sampling plans for the exponential distribution with progressive hybrid censoring”

Lin et al. [Exact Bayesian variable sampling plans for the exponential distribution with progressive hybrid censoring, J. Stat. Comput. Simul. 81 (2011), pp. 873–882] claimed to have derived exact Bayesian sampling plans for exponential distributions with progressive hybrid censoring. We comment on the accuracy of the design parameters of their proposed sampling plans and the associated Bayes risks given in tables of Lin et al. [Exact Bayesian variable sampling plans for the exponential distribution with progressive hybrid censoring, J. Stat. Comput. Simul. 81 (2011), pp. 873–882]. Counter-examples to their claim are provided.     

On the efficiency property of the linear estimators in the bivariate pearson type vii distribution

In this paper the efficiency property of the estimators of the parameters of the bivariate Pearson type VII distribution is studied inside the family of linear estimators, assuming that the sample is constituted by dependent random vectors. It is proven that, although there are not efficient linear estimators, the sample mean and the sample covariance matrix (affected by an unbiasedness weighting) are unbiased linear estimators of minimum distance to the Cramér-Rao lower bound. Finally, a numerical simulation example shows that the proposed estimators are computationally feasible.     

Goodness-of-fit tests via ϕ-measures of divergence for censored data

Measures of divergence or discrepancy are used extensively in statistics in various fields. In this article, we are focusing on divergence measures that are based on a class of measures known as Csiszar's divergence measures. In particular, we propose a class of goodness-of-fit tests based on Csiszar's class of measures designed for censored survival or reliability data. Further, we derive the asymptotic distribution of the test statistic under simple and composite null hypotheses as well as under contiguous alternative hypotheses. Simulations are furnished and real data are analysed to show the performance of the proposed tests for different ?-divergence measures.     

A power study of goodness-of-fit tests for multivariate normality implemented in R

Multivariate statistical analysis procedures often require data to be multivariate normally distributed. Many tests have been developed to verify if a sample could indeed have come from a normally distributed population. These tests do not all share the same sensitivity for detecting departures from normality, and thus a choice of test is of central importance. This study investigates through simulated data the power of those tests for multivariate normality implemented in the statistic software R and pits them against the variant of testing each marginal distribution for normality. The results of testing two-dimensional data at a level of significance α=5% showed that almost one-third of those tests implemented in R do not have a type I error below this. Other tests outperformed the naive variant in terms of power even when the marginals were not normally distributed. Even though no test was consistently better than all alternatives with every alternative distribution, the energy-statistic test always showed relatively good power across all tested sample sizes.     

Statistical inference for the extreme value distribution under adaptive Type-II progressive censoring schemes

Adaptive Type-II progressive censoring schemes have been shown to be useful in striking a balance between statistical estimation efficiency and the time spent on a life-testing experiment. In this article, some general statistical properties of an adaptive Type-II progressive censoring scheme are first investigated. A bias correction procedure is proposed to reduce the bias of the maximum likelihood estimators (MLEs). We then focus on the extreme value distributed lifetimes and derive the Fisher information matrix for the MLEs based on these properties. Four different approaches are proposed to construct confidence intervals for the parameters of the extreme value distribution. Performance of these methods is compared through an extensive Monte Carlo simulation.     

Analysis of simple step-stress model in presence of competing risks

ABSTRACT

In this article, we consider a simple step-stress life test in the presence of exponentially distributed competing risks. It is assumed that the stress is changed when a pre-specified number of failures takes place. The data is assumed to be Type-II censored. We obtain the maximum likelihood estimators of the model parameters and the exact conditional distributions of the maximum likelihood estimators. Based on the conditional distribution, approximate confidence intervals (CIs) of unknown parameters have been constructed. Percentile bootstrap CIs of model parameters are also provided. Optimal test plan is addressed. We perform an extensive simulation study to observe the behaviour of the proposed method. The performances are quite satisfactory. Finally we analyse two data sets for illustrative purposes.     

Ml estimation in the poisson binomial distribution with grouped data via the em algorithm

The maximum likelihood estimation of parameters of the Poisson binomial distribution, based on a sample with exact and grouped observations, is considered by applying the EM algorithm (Dempster et al, 1977). The results of Louis (1982) are used in obtaining the observed information matrix and accelerating the convergence of the EM algorithm substantially. The maximum likelihood estimation from samples consisting entirely of complete (Sprott, 1958) or grouped observations are treated as special cases of the estimation problem mentioned above. A brief account is given for the implementation of the EM algorithm when the sampling distribution is the Neyman Type A since the latter is a limiting form of the Poisson binomial. Numerical examples based on real data are included.     

Change point-cure models with application to estimating the change-point effect of age of diagnosis among prostate cancer patients

Previous research on prostate cancer survival trends in the United States National Cancer Institute's Surveillance Epidemiology and End Results database has indicated a potential change-point in the age of diagnosis of prostate cancer around age 50. Identifying a change-point value in prostate cancer survival and cure could have important policy and health care management implications. Statistical analysis of this data has to address two complicating features: (1) change-point models are not smooth functions and so present computational and theoretical difficulties; and (2) models for prostate cancer survival need to account for the fact that many men diagnosed with prostate cancer can be effectively cured of their disease with early treatment. We develop a cure survival model that allows for change-point effects in covariates to investigate a potential change-point in the age of diagnosis of prostate cancer. Our results do not indicate that age under 50 is associated with increased hazard of death from prostate cancer.     

An index of local sensitivity to non-ignorability for parametric survival models with potential non-random missing covariate: an application to the SEER cancer registry data

Several survival regression models have been developed to assess the effects of covariates on failure times. In various settings, including surveys, clinical trials and epidemiological studies, missing data may often occur due to incomplete covariate data. Most existing methods for lifetime data are based on the assumption of missing at random (MAR) covariates. However, in many substantive applications, it is important to assess the sensitivity of key model inferences to the MAR assumption. The index of sensitivity to non-ignorability (ISNI) is a local sensitivity tool to measure the potential sensitivity of key model parameters to small departures from the ignorability assumption, needless of estimating a complicated non-ignorable model. We extend this sensitivity index to evaluate the impact of a covariate that is potentially missing, not at random in survival analysis, using parametric survival models. The approach will be applied to investigate the impact of missing tumor grade on post-surgical mortality outcomes in individuals with pancreas-head cancer in the Surveillance, Epidemiology, and End Results data set. For patients suffering from cancer, tumor grade is an important risk factor. Many individuals in these data with pancreas-head cancer have missing tumor grade information. Our ISNI analysis shows that the magnitude of effect for most covariates (with significant effect on the survival time distribution), specifically surgery and tumor grade as some important risk factors in cancer studies, highly depends on the missing mechanism assumption of the tumor grade. Also a simulation study is conducted to evaluate the performance of the proposed index in detecting sensitivity of key model parameters.     

Optimum Design for Type-I Step-stress Accelerated Life Tests of Two-parameter Weibull Distributions

In this article, we focus on the general k-step step-stress accelerated life tests with Type-I censoring for two-parameter Weibull distributions based on the tampered failure rate (TFR) model. We get the optimum design for the tests under the criterion of the minimization of the asymptotic variance of the maximum likelihood estimate of the pth percentile of the lifetime under the normal operating conditions. Optimum test plans for the simple step-stress accelerated life tests under Type-I censoring are developed for the Weibull distribution and the exponential distribution in particular. Finally, an example is provided to illustrate the proposed design and a sensitivity analysis is conducted to investigate the robustness of the design.