Rate-optimal nonparametric estimation in classical and Berkson errors-in-variables problems

We consider nonparametric estimation of a regression curve when the data are observed with Berkson errors or with a mixture of classical and Berkson errors. In this context, other existing nonparametric procedures can either estimate the regression curve consistently on a very small interval or require complicated inversion of an estimator of the Fourier transform of a nonparametric regression estimator. We introduce a new estimation procedure which is simpler to implement, and study its asymptotic properties. We derive convergence rates which are faster than those previously obtained in the literature, and we prove that these rates are optimal. We suggest a data-driven bandwidth selector and apply our method to some simulated examples.     

A semiparametric pseudo-score method for analysis of two-phase studies with continuous phase-I covariates

Two-phase study designs can reduce cost and other practical burdens associated with large scale epidemiologic studies by limiting ascertainment of expensive covariates to a smaller but informative sub-sample (phase-II) of the main study (phase-I). During the analysis of such studies, however, subjects who are selected at phase-I but not at phase-II, remain informative as they may have partial covariate information. A variety of semi-parametric methods now exist for incorporating such data from phase-I subjects when the covariate information can be summarized into a finite number of strata. In this article, we consider extending the pseudo-score approach proposed by Chatterjee et al. (J Am Stat Assoc 98:158–168, 2003) using a kernel smoothing approach to incorporate information on continuous phase-I covariates. Practical issues and algorithms for implementing the methods using existing software are discussed. A sandwich-type variance estimator based on the influence function representation of the pseudo-score function is proposed. Finite sample performance of the methods are studies using simulated data. Advantage of the proposed smoothing approach over alternative methods that use discretized phase-I covariate information is illustrated using two-phase data simulated within the National Wilms Tumor Study (NWTS).     

Survival analysis for the inverse Gaussian distribution with the Gibbs sampler

This paper describes a comprehensive survival analysis for the inverse Gaussian distribution employing Bayesian and Fiducial approaches. It focuses on making inferences on the inverse Gaussian (IG) parameters μ and λ and the average remaining time of censored units. A flexible Gibbs sampling approach applicable in the presence of censoring is discussed and illustrations with Type II, progressive Type II, and random rightly censored observations are included. The analyses are performed using both simulated IG data and empirical data examples. Further, the bootstrap comparisons are made between the Bayesian and Fiducial estimates. It is concluded that the shape parameter ( ϕ=λ/μ) of the inverse Gaussian distribution has the most impact on the two analyses, Bayesian vs. Fiducial, and so does the size of censoring in data to a lesser extent. Overall, both these approaches are effective in estimating IG parameters and the average remaining lifetime. The suggested Gibbs sampler allowed a great deal of flexibility in implementation for all types of censoring considered.     

Correction locale de l'estimateur à noyau de la densité d'une loi de probabilité

The standard Parzen-Rosenblatt kernel density estimator is known to systematically deviate from the true value near critical points of the density curve. To overcome this difficulty, we extend the Rao-Blackwell method by using locally sufficient statistics: we define a new estimator and study its asymptotic behaviour. The interest of the method is shown by means of simulations.     

Double-blind deconvolution: the analysis of post-synaptic currents in nerve cells

This paper is concerned with the analysis of observations made on a system that is being stimulated at fixed time intervals but where the precise nature and effect of any individual stimulus is unknown. The realized values are modelled as a stochastic process consisting of a random signal embedded in noise. The aim of the analysis is to use the data to unravel the unknown structure of the system and to ascertain the probabilistic behaviour of the stimuli. A method of parameter estimation based on quasi-profile likelihood is presented and the statistical properties of the estimates are established while recognizing that there will be a discrepancy between the model and the true data-generating mechanism. A method of model validation and determination is also advanced and kernel smoothing techniques are proposed as a basis for identifying the amplitude distribution of the stimuli. The data processing techniques described have a direct application to the investigation of excitatory post-synaptic currents recorded from nerve cells in the central nervous system and their use in quantal analysis of such data is illustrated.     

对支持向量机混合核函数方法的再评估

混合核函数方法并没有解决核函数的选择问题,只是将问题等价转换为权重参数的选择。同时该方法还需要分别为两个核函数确定参数,大大增加了算法的复杂程度,限制了支持向量机的泛化能力。事实上,调节核函数的参数对分类结果的影响要远大于选择什么类型的核函数,因此混合核函数方法实属“避轻就重”。实证分析表明,不同核函数对应的共同支持向量比例很高,存在很大程度的一致性,线性组合的意义并不大,这也是混合核函数方法无法有效提升分类性能的一个重要原因。     

Nonparametric Estimation of the Geometric Vitality Function

Recently, Nair and Rajesh (2000 Nair , K. R. M. , Rajesh , G. ( 2000 ). Geometric vitality function and its application to reliability . IAPQR Tran. 25 ( 1 ): 1 – 8 . [Google Scholar]) proposed a measure to describe the failure pattern of components/devices in terms of the geometric mean of the residual life. This measure find applications in modeling life time data. In the present work we provide a nonparametric kernel-type estimator for the geometric vitality function, both in the case of complete and censored samples. The properties of the estimator, under certain regularity conditions, are studied. The performance of the estimator is compared with the empirical estimator using a real data set and simulation studies are carried out using the Monte Carlo method.