Optimal designs for experiments with mixtures: a survey

This is a survey article on known results about analytic solutions and numerical solutions of optimal designs for various regression models for experiments with mixtures. The regression models include polynomial models, models containing homogeneous functions, models containing inverse terms and ratios, log contrast models, models with quantitative variables, and mod els containing the amount of mixture, Optimality criteria considered include D-, A-, E-,φ_p- and I_λ-Optimalities. Uniform design and uniform optimal design for mixture components, and efficiencies of the {q,2} simplex-controid design are briefly discussed.     

Optimal block designs for double cross experiments

ABSTRACT

This paper presents systematic methods of construction of optimal block designs for a double cross experiments for both even and odd values of “p” parental lines. The both even and odd values of designs are derived by using initial block of unreduced balanced incomplete block designs and initial block of row–column designs given by Bose et al. (1953 Bose, R.C., Shrikhande, S.S., Bhattacharya, K.N. (1953). On the construction of group divisible incomplete block design. Ann. Math. Stat. 24:167–195.[Crossref] , [Google Scholar]) and Gupta and Choi (1998 Gupta, S., Choi, K.C. (1998). Optimal row-column designs for complete diallel crosses. Commun. Stat. Theory Methods 27(11):2827–2835.[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]), respectively. In this attempt we have found some new universally optimal block designs for double cross experiments.     

Admissibility of a variance estimator in finite population sampling under Warner's randomized response plan with multiple responses

ABSTRACT

Let P be the proportion of individuals in a finite population possessing a sensitive attribute. We consider the problem of unbiased estimation of (i) the variance of a linear unbiased estimator of P and (ii) the population variance P (1—P) for a given probability sampling design under Warner's (1965 Warner, S.L. (1965). Randomized response - A survey technique for eliminating evasive answer bias. J. Amer. Statist. Assoc. 60:63–69.[Taylor & Francis Online], [Web of Science ®] , [Google Scholar]) randomized response (RR) plan when independent responses are obtained from each sampled individual as many times as he/she is selected in the sample and prove the admissibility of a quadratic unbiased estimator for each.     

The robust economic statistical design of the Hotelling's T2 chart

ABSTRACT

Economic statistical designs aim at minimizing the cost of process monitoring when a specific scenario or a set of estimated process and cost parameters is given. But, in practice the process may be affected by more than one scenario which may lead to severe cost penalties if the wrong design is used. Here, we investigate the robust economic statistical design (RESD) of the T² chart in an attempt to reduce these cost penalties when there are multiple scenarios. Our method is to employ the genetic algorithm (GA) optimization method to minimize the total expected monitoring cost across all distinct scenarios. We illustrate the effectiveness of the method using two numerical examples. Simulation studies indicate that robust economic statistical designs should be encouraged in practice.     

Optimal designs for estimating a choice hierarchy by a general nested multinomial logit model

Abstract

In choice experiments the process of decision-making can be more complex than the proposed by the Multinomial Logit Model (MNL). In these scenarios, models such as the Nested Multinomial Logit Model (NMNL) are often employed to model a more complex decision-making. Understanding the decision-making process is important in some fields such as marketing. Achieving a precise estimation of the models is crucial to the understanding of this process. To do this, optimal experimental designs are required. To construct an optimal design, information matrix is key. A previous research by others has developed the expression for the information matrix of the two-level NMNL model with two nests: Alternatives nest (J alternatives) and No-Choice nest (1 alternative). In this paper, we developed the likelihood function for a two-stage NMNL model for M nests and we present the expression for the information matrix for 2 nests with any amount of alternatives in them. We also show alternative D-optimal designs for No-Choice scenarios with similar relative efficiency but with less complex alternatives which can help to obtain more reliable answers and one application of these designs.     

Uniform Design for Experiments with Mixtures

The goal of uniform mixture design is to scatter the design points in the experimental region uniformly. The commonly used criteria, such as mean square distance, are based on the Euclidean distance. Based on the Lee distance, a new criterion is proposed in this article. And an algorithm, called NTLBG, is also proposed to refine the randomly generated design for the experimental design with mixtures. Some examples show that the design generated by the NTLBG algorithm has a lower criteria value.     

An Extension of Economic Design of x-Bar Control Charts for Non Normally Distributed Data Under Weibull Shock Models

Three parameters—sample size, sampling intervals, and the control limits—must be determined when the x bar chart to monitor a manufacturing process. The constant sampling intervals were widely employed because of its administrative simplicity. However, the variable sampling interval (VSI) has recently been shown to give substantially faster detection of most process shifts than fixed-sampling-interval (FSI) for x-bar charts. In addition, these measurements in the subgroup are assumed to be normally distributed. That assumption may not be tenable. This investigation compares the economic design of x-bar control charts for non normal data under Weibull shock models with various sampling avenues.     

Computer-Generated Change-Over Designs for Correlated Observations

Change-over designs with independently distributed errors in the model have been studied extensively in the literature. Martin and Eccleston (2001 Martin , R. J. , Eccleston , J. A. ( 2001 ). Optimal and near optimal designs for dependent observations . Statist. Applic. 3 : 101 – 116 . [Google Scholar]) gave an algorithm for the generation of efficient change-over designs when the errors are correlated. This article proposes an algorithm for the generation of efficient change-over designs for estimation of direct effects of treatments in the presence of first-order residual effects in the model and when the errors are correlated.     

Adaptive Crossover Design for Normal Responses

In a response-adaptive design, we review and update the trial on the basis of outcomes in order to achive a specific goal. In clinical trials our goal is to allocate a larger number of patients to the better treatment. In the present paper, we use a response adaptive design in a two-treatment two-period crossover trial where the treatment responses are continuous. We provide probability measures to choose between the possible treatment combinations AA, AB, BA, or BB. The goal is to use the better treatment combination a larger number of times. We calculate the allocation proportions to the possible treatment combinations and their standard errors. We also derive some asymptotic results and provide solutions on related inferential problems. The proposed procedure is compared with a possible competitor. Finally, we use a data set to illustrate the applicability of our proposed design.