Generalised K-S confidence regions: some exact results

One-sided confidence regions for continuous cumulative distribution function are constructed using empirical cumulative distribution functions and the generalized Kolmogorov-Smirnov distance. The band width of such regions becomes narrower in the right or left tail of the distribution. Significance levels necessary for implementation are given. Some other K-S type distances useful in constructing a confidence region with nonconstant width are also included.     

Adaptive designs for single‐arm phase II trials in oncology

Clinical phase II trials in oncology are conducted to determine whether the activity of a new anticancer treatment is promising enough to merit further investigation. Two‐stage designs are commonly used for this situation to allow for early termination. Designs proposed in the literature so far have the common drawback that the sample sizes for the two stages have to be specified in the protocol and have to be adhered to strictly during the course of the trial. As a consequence, designs that allow a higher extent of flexibility are desirable. In this article, we propose a new adaptive method that allows an arbitrary modification of the sample size of the second stage using the results of the interim analysis or external information while controlling the type I error rate. If the sample size is not changed during the trial, the proposed design shows very similar characteristics to the optimal two‐stage design proposed by Chang et al. (Biometrics 1987; 43:865–874). However, the new design allows the use of mid‐course information for the planning of the second stage, thus meeting practical requirements when performing clinical phase II trials in oncology. Copyright © 2012 John Wiley & Sons, Ltd.     

The Kumaraswamy GEV distribution

The popular generalized extreme value (GEV) distribution has not been a flexible model for extreme values in many areas. We propose a generalization – referred to as the Kumaraswamy GEV distribution – and provide a comprehensive treatment of its mathematical properties. We estimate its parameters by the method of maximum likelihood and provide the observed information matrix. An application to some real data illustrates flexibility of the new model. Finally, some bivariate generalizations of the model are proposed.     

Permutation tests of scale using deviances

Robust tests for comparing scale parameters, based on deviances—absolute deviations from the median—are examined. Higgins (2004) proposed a permutation test for comparing two treatments based on the ratio of deviances, but the performance of this procedure has not been investigated. A simulation study examines the performance of Higgins’ test relative to other tests of scale utilizing deviances that have been shown in the literature to have good properties. An extension of Higgins’ procedure to three or more treatments is proposed, and a second simulation study compares its performance to other omnibus tests for comparing scale. While no procedure emerged as a preferred choice in every scenario, Higgins’ tests are found to perform well overall with respect to Type I error rate and power.     

Stochastic comparisons between extreme order statistics from scale models

Stochastic ordering relations between extreme order statistics from exponential, Weibull and gamma distributions have been studied extensively by many researchers in recent years. In this work, we obtain various ordering results for the comparisons of two extreme order statistics from scale models when one set of scale parameters majorizes the other. The new results obtained here are applied when the baseline distributions are exponentiated Weibull or generalized gamma distributions. In this way, we generalize and extend some results established recently in the literature.     

经管类专业《统计学》教学中应融入数学模型思想

针对经管类专业学生统计学学习中重应用、轻理论的现状,在教学中融入模型思想,通过规范统计学中参数估计、假设检验、方差分析等几类问题的数学模型建立,加强学生对统计学问题的理解和学习。     

Two non parametric methods for change-point detection in distribution

The change-point detection problem is determining whether a change has taken place. Two non parametric methods based on empirical likelihood and the likelihood ratio are proposed for detecting a change-point problem in distributions for independent observations. Numerical studies are carried out to evaluate the performance of the proposed methods. The simulation results demonstrate that the proposed methods are robust, that is, they perform well regardless of whether the observations are from the same distribution family.     

Pitman closeness,monotonicity and consistency of best linear unbiased and invariant estimators for exponential distribution under Type II censoring

Comparisons of best linear unbiased estimators with some other prominent estimators have been carried out over the last 50 years since the ground breaking work of Lloyd [E.H. Lloyd, Least squares estimation of location and scale parameters using order statistics, Biometrika 39 (1952), pp. 88–95]. These comparisons have been made under many different criteria across different parametric families of distributions. A noteworthy one is by Nagaraja [H.N. Nagaraja, Comparison of estimators and predictors from two-parameter exponential distribution, Sankhyā Ser. B 48 (1986), pp. 10–18], who made a comparison of best linear unbiased (BLUE) and best linear invariant (BLIE) estimators in the case of exponential distribution. In this paper, continuing along the same lines by assuming a Type II right censored sample from a scaled-exponential distribution, we first compare BLUE and BLIE of the exponential mean parameter in terms of Pitman closeness (nearness) criterion. We show that the BLUE is always Pitman closer than the BLIE. Next, we introduce the notions of Pitman monotonicity and Pitman consistency, and then establish that both BLUE and BLIE possess these two properties.     

Asymptotic expaxsioxs for the joint distribution of cirrelated hotellings t2 statlstics under normality

Let T² _i=z′_iS^?1z_i, i==,…k be correlated Hotelling's T² statistics under normality. where z=(z′_i,…,z′_k)′ and nS are independently distributed as N_kp((O,ρ?∑) and Wishart distribution W_p(∑, n), respectively. The purpose of this paper is to study the distribution function F(x₁,…,x_k) of (T² _i,…,T² _k) when n is large. First we derive an asymptotic expansion of the characteristic function of (T² _i,…,T² _k) up to the order n^?2. Next we give asymptotic expansions for (T² _i,…,T² _k) in two cases (i)ρ=I_k and (ii) k=2 by inverting the expanded characteristic function up to the orders n^?2 and n^?1, respectively. Our results can be applied to the distribution function of max (T² _i,…,T² _k) as a special case.     

The estimation of treatment effect for the censored bivariate data under the univariate censoring

This paper establishes a nonparametric estimator for the treatment effect on censored bivariate data under unvariate censoring. This proposed estimator is based on the one from Lin and Ying(1993)'s nonparametric bivariate survival function estimator, which is itself a generalized version of Park and Park(1995)' quantile estimator. A Bahadur type representation of quantile functions were obtained from the marginal survival distribution estimator of Lin and Ying' model. The asymptotic property of this estimator is shown below and the simulation studies are also given