Local predictive influence in bayesian linear models with conjugate priors

Cook (1986) presented the idea of local influence to study the sensitivity of inferences to model assumptions:introduce a vector δ of perturbations to the model; choose a discrepancy function D to measure differences between the original inference and the inference under the perturbed model; study the behavior of D near δ = 0, the original model, usually by taking derivatives. Johnson and Geisser (1983) measure influence in Bayesian inference by the Kullback-Leibler divergence between predictive distributions. I~IcCulloch (1989) is a synthesis of Cook and Johnson and Geisser, using Kullback-Leibler divergence between posterior or predictive distributions as the discrepancy function in Bayesian local influence analyses. We analyze a special case for which McCulloch gives the general theory; namely, the linear model with conjugate prior. We present specific formulae for local influence measures for 1) changes in the parameters of the gamma prior for the precision, 2) changes in the mean of the normal prior for the regression coefficients, 3) changes in the covariance matrix of the normal prior for the regression coefficients and 4) changes in the case weights. Our method is an easy way to find locally influential subsets of points without knowing in advance the sizes of the subsets. The techniques are illustrated with a regression example.     

A robust process capability index

The existing process capability indices (PCI's) assume that the distribution of the process being investigated is normal. For non-normal distributions, PCI's become unreliable in that PCI's may indicate the process is capable when in fact it is not. In this paper, we propose a new index which can be applied to any distribution. The proposed indexC_f:, is directly related to the probability of non-conformance of the process. For a given random sample, the estimation of C_f boils down to estimating non-parametrically the tail probabilities of an unknown distribution. The approach discussed in this paper is based on the works by Pickands (1975) and Smith (1987). We also discuss the construction of bootstrap confidence intervals of C_f: based on the so-called accelerated bias correction method (BC _a:). Several simulations are carried out to demonstrate the flexibility and applicability of C_f:. Two real life data sets are analyzed using the proposed index.     

Optimal allocation of time points for the random effects model

In this article the problem of the optimal selection and allocation of time points in repeated measures experiments is considered. D‐ optimal designs for linear regression models with a random intercept and first order auto‐regressive serial correlations are computed numerically and compared with designs having equally spaced time points. When the order of the polynomial is known and the serial correlations are not too small, the comparison shows that for any fixed number of repeated measures, a design with equally spaced time points is almost as efficient as the D‐ optimal design. When, however, there is no prior knowledge about the order of the underlying polynomial, the best choice in terms of efficiency is a D‐ optimal design for the highest possible relevant order of the polynomial. A design with equally‐spaced time points is the second best choice     

Asymptotic relative efficiency of wald tests in measurement error models

In this paper, asymptotic relative efficiency (ARE) of Wald tests for the Tweedie class of models with log-linear mean, is considered when the aux¬iliary variable is measured with error. Wald test statistics based on the naive maximum likelihood estimator and on a consistent estimator which is obtained by using Nakarnura's (1990) corrected score function approach are defined. As shown analytically, the Wald statistics based on the naive and corrected score function estimators are asymptotically equivalents in terms of ARE. On the other hand, the asymptotic relative efficiency of the naive and corrected Wald statistic with respect to the Wald statistic based on the true covariate equals to the square of the correlation between the unobserved and the observed co-variate. A small scale numerical Monte Carlo study and an example illustrate the small sample size situation.     

A class of semiparametric transormation frailty models with application to estimating treatment effects and heterogenity in aids clinical traials

Muitivariate failure time data are common in medical research; com¬monly used statistical models for such correlated failure-time data include frailty and marginal models. Both types of models most often assume pro¬portional hazards (Cox, 1972); but the Cox model may not fit the data well This article presents a class of linear transformation frailty models that in¬cludes, as a special case, the proportional hazards model with frailty. We then propose approximate procedures to derive the best linear unbiased es¬timates and predictors of the regression parameters and frailties. We apply the proposed methods to analyze results of a clinical trial of different dose levels of didansine (ddl) among HIV-infected patients who were intolerant of zidovudine (ZDV). These methods yield estimates of treatment effects and of frailties corresponding to patient groups defined by clinical history prior to entry into the trial.     

Generalized additive mixed models

Following the extension from linear mixed models to additive mixed models, extension from generalized linear mixed models to generalized additive mixed models is made, Algorithms are developed to compute the MLE's of the nonlinear effects and the covariance structures based on the penalized marginal likelihood. Convergence of the algorithms and selection of the smooth param¬eters are discussed.     

Long memory stochastic volatility : A bayesian approach

We propose a simulation-based Bayesian approach to the analysis of long memory stochastic volatility models, stationary and nonstationary. The main tool used to reduce the likelihood function to a tractable form is an approximate state-space representation of the model, A data set of stock market returns is analyzed with the proposed method. The approach taken here allows a quantitative assessment of the empirical evidence in favor of the stationarity, or nonstationarity, of the instantaneous volatility of the data.     

A generalization of the compound rayleigh distribution: using a bayesian method on cancer survival times

In this paper the generalized compound Rayleigh model, exhibiting flexible hazard rate, is high¬lighted. This makes it attractive for modelling survival times of patients showing characteristics of a random hazard rate. The Bayes estimators are derived for the parameters of this model and some survival time parameters from a right censored sample. This is done with respect to conjugate and discrete priors on the parameters of this model, under the squared error loss function, Varian's asymmetric linear-exponential (linex) loss function and a weighted linex loss function. The future survival time of a patient is estimated under these loss functions. A Monte Carlo simu¬lation procedure is used where closed form expressions of the estimators cannot be obtained. An example illustrates the proposed estimators for this model.     

Posterior analysis,prediction and reliability in three-parameter weibull distributions

The paper develops Bayesian analysis in the context of samples from three-parameter Weibull distributions and shows how to tackle the problems of prediction and estimation of reliability curves. As Johnson, Kotz and Balakrishnan ( 1994 ) mentioned, the prediction problems for the three-parameter Weibull model seem to be unresolved and is certainly worth looking into (p.671). Posterior analysis organized around Gibbs sampling is shown to perform well. An application to stock returns is used to illustrate the potential of the approach.