启动农村消费的障碍及消除障碍的路径选择研究

消费是拉动内需,推动经济持续、健康发展的不懈动力,然而现阶段我国居民消费对GDP增长的促进作用较弱,尤其是农村消费,但由于受收入、物价、市场发达程度等因素的制约,农村消费长期以来一直被压制.采用定量、定性相结合的分析方法,通过构造数量模型分析影响消费的主要因素及影响程度,在此基础上重点对影响农村消费增长的原因进行分析,并提出相应的解决措施.     

Analysis of microtubule dynamics using growth curve models

Microtubules are part of the structural network within a cell's cytoplasm, providing structural support as well as taking part in many of the cellular processes. A large body of data provide evidence that dynamics of microtubules in a cell is reponsible for the performance of many critical cellular functions such as cell division. In this article, we study the effect of four different isoforms of a protein tau on microtubule dynamics using growth curve models. The results show that a linear growth curve model is sufficient to explain the data. Moreover, we find that a mutated version of a 3-repeat tau protein has a similar effect as a 4-repeat tau protein on microtubule dynamics. The latter findings conform with the biological understanding of the effect of the protein tau on microtubule dynamics.     

A copula-based Markov chain model for the analysis of binary longitudinal data

A fully parametric first-order autoregressive (AR(1)) model is proposed to analyse binary longitudinal data. By using a discretized version of a copula, the modelling approach allows one to construct separate models for the marginal response and for the dependence between adjacent responses. In particular, the transition model that is focused on discretizes the Gaussian copula in such a way that the marginal is a Bernoulli distribution. A probit link is used to take into account concomitant information in the behaviour of the underlying marginal distribution. Fixed and time-varying covariates can be included in the model. The method is simple and is a natural extension of the AR(1) model for Gaussian series. Since the approach put forward is likelihood-based, it allows interpretations and inferences to be made that are not possible with semi-parametric approaches such as those based on generalized estimating equations. Data from a study designed to reduce the exposure of children to the sun are used to illustrate the methods.     

Approximating the risk score for disease diagnosis using MARS

In disease screening and diagnosis, often multiple markers are measured and combined to improve the accuracy of diagnosis. McIntosh and Pepe [Combining several screening tests: optimality of the risk score, Biometrics 58 (2002), pp. 657–664] showed that the risk score, defined as the probability of disease conditional on multiple markers, is the optimal function for classification based on the Neyman–Pearson lemma. They proposed a two-step procedure to approximate the risk score. However, the resulting receiver operating characteristic (ROC) curve is only defined in a subrange (L, h) of false-positive rates in (0,1) and the determination of the lower limit L needs extra prior information. In practice, most diagnostic tests are not perfect, and it is usually rare that a single marker is uniformly better than the other tests. Using simulation, I show that multivariate adaptive regression spline is a useful tool to approximate the risk score when combining multiple markers, especially when ROC curves from multiple tests cross. The resulting ROC is defined in the whole range of (0,1) and is easy to implement and has intuitive interpretation. The sample code of the application is shown in the appendix.     

Change-Point Tests for the Error Distribution in Non-parametric Regression

Abstract.  Several testing procedures are proposed that can detect change-points in the error distribution of non-parametric regression models. Different settings are considered where the change-point either occurs at some time point or at some value of the covariate. Fixed as well as random covariates are considered. Weak convergence of the suggested difference of sequential empirical processes based on non-parametrically estimated residuals to a Gaussian process is proved under the null hypothesis of no change-point. In the case of testing for a change in the error distribution that occurs with increasing time in a model with random covariates the test statistic is asymptotically distribution free and the asymptotic quantiles can be used for the test. This special test statistic can also detect a change in the regression function. In all other cases the asymptotic distribution depends on unknown features of the data-generating process and a bootstrap procedure is proposed in these cases. The small sample performances of the proposed tests are investigated by means of a simulation study and the tests are applied to a data example.     

Robust nonparametric estimation with missing data

In this paper, under a nonparametric regression model, we introduce two families of robust procedures to estimate the regression function when missing data occur in the response. The first proposal is based on a local M$M$-functional applied to the conditional distribution function estimate adapted to the presence of missing data. The second proposal imputes the missing responses using the local M$M$-smoother based on the observed sample and then estimates the regression function with the completed sample. We show that the robust procedures considered are consistent and asymptotically normally distributed. A robust procedure to select the smoothing parameter is also discussed.     

A comparison of nonparametric priors in hierarchical mixture modelling for AFT regression

We will pursue a Bayesian nonparametric approach in the hierarchical mixture modelling of lifetime data in two situations: density estimation, when the distribution is a mixture of parametric densities with a nonparametric mixing measure, and accelerated failure time (AFT) regression modelling, when the same type of mixture is used for the distribution of the error term. The Dirichlet process is a popular choice for the mixing measure, yielding a Dirichlet process mixture model for the error; as an alternative, we also allow the mixing measure to be equal to a normalized inverse-Gaussian prior, built from normalized inverse-Gaussian finite dimensional distributions, as recently proposed in the literature. Markov chain Monte Carlo techniques will be used to estimate the predictive distribution of the survival time, along with the posterior distribution of the regression parameters. A comparison between the two models will be carried out on the grounds of their predictive power and their ability to identify the number of components in a given mixture density.     

Nonparametric estimation of waiting time distributions in a Markov model based on current status data

We construct nonparametric estimators of state waiting time distribution functions in a Markov multistate model using current status data. This is a particularly difficult problem since neither the entry nor the exit times of a given state are directly observed. These estimators are obtained, using the Markov property, from estimators of counting processes of state entry and exit times, as well as, the size of “at risk” sets of state entry and transitions out of that state. Consistency of our estimators is established. Finite-sample behavior of our estimators is studied by simulation, in which we show that our estimators based on current status data compare well with those based on complete data. We also illustrate our method using a pubertal development data set obtained from the NHANES III [1997. NHANES III Reference Manuals and Reports (CD-ROM). Analytic and Reporting Guidelines: The Third National Health and Nutrition Examination Survey (1988–94). National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD] study.     

Quasi-minimax estimation in the general linear regression model

This paper is mainly concerned with minimax estimation in the general linear regression model y=Xβ+ε$y=X\beta +\epsilon$ under ellipsoidal restrictions on the parameter space and quadratic loss function. We confine ourselves to estimators that are linear in the response vector y  . The minimax estimators of the regression coefficient β$\beta$ are derived under homogeneous condition and heterogeneous condition, respectively. Furthermore, these obtained estimators are the ridge-type estimators and mean dispersion error (MDE) superior to the best linear unbiased estimator b=(X^′W^-1X)^-1X^′W^-1y$b=(X^{\prime }{W}^{-1}X{)}^{-1}{X}^{\prime }{W}^{-1}y$ under some conditions.     

A ‘nondecimated’ lifting transform

Classical nondecimated wavelet transforms are attractive for many applications. When the data comes from complex or irregular designs, the use of second generation wavelets in nonparametric regression has proved superior to that of classical wavelets. However, the construction of a nondecimated second generation wavelet transform is not obvious. In this paper we propose a new ‘nondecimated’ lifting transform, based on the lifting algorithm which removes one coefficient at a time, and explore its behavior. Our approach also allows for embedding adaptivity in the transform, i.e. wavelet functions can be constructed such that their smoothness adjusts to the local properties of the signal. We address the problem of nonparametric regression and propose an (averaged) estimator obtained by using our nondecimated lifting technique teamed with empirical Bayes shrinkage. Simulations show that our proposed method has higher performance than competing techniques able to work on irregular data. Our construction also opens avenues for generating a ‘best’ representation, which we shall explore.