State transition modeling of complex monitored health data

This article considers the analysis of complex monitored health data, where often one or several signals are reflecting the current health status that can be represented by a finite number of states, in addition to a set of covariates. In particular, we consider a novel application of a non-parametric state intensity regression method in order to study time-dependent effects of covariates on the state transition intensities. The method can handle baseline, time varying as well as dynamic covariates. Because of the non-parametric nature, the method can handle different data types and challenges under minimal assumptions. If the signal that is reflecting the current health status is of continuous nature, we propose the application of a weighted median and a hysteresis filter as data pre-processing steps in order to facilitate robust analysis. In intensity regression, covariates can be aggregated by a suitable functional form over a time history window. We propose to study the estimated cumulative regression parameters for different choices of the time history window in order to investigate short- and long-term effects of the given covariates. The proposed framework is discussed and applied to resuscitation data of newborns collected in Tanzania.     

Statistical inference based on generalized Lindley record values

This paper addresses the problems of frequentist and Bayesian estimation for the unknown parameters of generalized Lindley distribution based on lower record values. We first derive the exact explicit expressions for the single and product moments of lower record values, and then use these results to compute the means, variances and covariance between two lower record values. We next obtain the maximum likelihood estimators and associated asymptotic confidence intervals. Furthermore, we obtain Bayes estimators under the assumption of gamma priors on both the shape and the scale parameters of the generalized Lindley distribution, and associated the highest posterior density interval estimates. The Bayesian estimation is studied with respect to both symmetric (squared error) and asymmetric (linear-exponential (LINEX)) loss functions. Finally, we compute Bayesian predictive estimates and predictive interval estimates for the future record values. To illustrate the findings, one real data set is analyzed, and Monte Carlo simulations are performed to compare the performances of the proposed methods of estimation and prediction.     

Correlation in a Bayesian framework

The authors consider the correlation between two arbitrary functions of the data and a parameter when the parameter is regarded as a random variable with given prior distribution. They show how to compute such a correlation and use closed form expressions to assess the dependence between parameters and various classical or robust estimators thereof, as well as between p‐values and posterior probabilities of the null hypothesis in the one‐sided testing problem. Other applications involve the Dirichlet process and stationary Gaussian processes. Using this approach, the authors also derive a general nonparametric upper bound on Bayes risks.     

Confidence intervals based on the deviance statistic for the hyperparameters in state space models

The main objective of this work is to evaluate the performance of confidence intervals, built using the deviance statistic, for the hyperparameters of state space models. The first procedure is a marginal approximation to confidence regions, based on the likelihood test, and the second one is based on the signed root deviance profile. Those methods are computationally efficient and are not affected by problems such as intervals with limits outside the parameter space, which can be the case when the focus is on the variances of the errors. The procedures are compared to the usual approaches existing in the literature, which includes the method based on the asymptotic distribution of the maximum likelihood estimator, as well as bootstrap confidence intervals. The comparison is performed via a Monte Carlo study, in order to establish empirically the advantages and disadvantages of each method. The results show that the methods based on the deviance statistic possess a better coverage rate than the asymptotic and bootstrap procedures.     

Double robust estimator in general treatment regimes based on Covariate-balancing

Double robust estimators have double the chance of being a consistent estimator of a causal effect in binary treatments cases. In this paper, we proposed an estimator of a causal effect for general treatment regimes based on covariate-balancing. Under parametrical situation, our estimator has double robustness.     

Improved two-parameter estimators for the negative binomial and Poisson regression models

Negative binomial regression (NBR) and Poisson regression (PR) applications have become very popular in the analysis of count data in recent years. However, if there is a high degree of relationship between the independent variables, the problem of multicollinearity arises in these models. We introduce new two-parameter estimators (TPEs) for the NBR and the PR models by unifying the two-parameter estimator (TPE) of Özkale and Kaç?ranlar [The restricted and unrestricted two-parameter estimators. Commun Stat Theory Methods. 2007;36:2707–2725]. These new estimators are general estimators which include maximum likelihood (ML) estimator, ridge estimator (RE), Liu estimator (LE) and contraction estimator (CE) as special cases. Furthermore, biasing parameters of these estimators are given and a Monte Carlo simulation is done to evaluate the performance of these estimators using mean square error (MSE) criterion. The benefits of the new TPEs are also illustrated in an empirical application. The results show that the new proposed TPEs for the NBR and the PR models are better than the ML estimator, the RE and the LE.     

MSE performance of the weighted average estimators consisting of shrinkage estimators when each individual regression coefficient is estimated

In this paper, we analytically derive the exact formula for the mean squared error (MSE) of two weighted average (WA) estimators for each individual regression coefficient. Further, we execute numerical evaluations to investigate small sample properties of the WA estimators, and compare the MSE performance of the WA estimators with the other shrinkage estimators and the usual OLS estimator. Our numerical results show that (1) the WA estimators have smaller MSE than the other shrinkage estimators and the OLS estimator over a wide region of parameter space; (2) the range where the relative MSE of the WA estimator is smaller than that of the OLS estimator gets narrower as the number of explanatory variables k increases.     

高频数据瞬时波动率核估计的窗宽选择及算法研究

在瞬时波动率的各种估计量中,非参数估计量因其能准确地度量瞬时波动率,一直是学者们的研究热点。然而,这类估计量在实际应用中都面临着最优窗宽的确定问题。由于最优窗宽中往往携带一些难以估计的未知参数,使得在实际应用过程中确定最优窗宽的具体数值存在困难。本文以瞬时波动率的核估计量为例,借鉴非参数回归分析中窗宽选择的思想,构建了一种能从数据中准确计算出最优窗宽具体值的算法。理论的分析和数值上的验证表明：文中所构建的算法具有良好的稳定性、适应性和收敛速度。算法的提出为瞬时波动率的后续应用研究铺平道路。     

基于股价预测的泛证券投资组合策略

本文基于期望效用最大化和L₁-中位数估计研究了在线投资组合选择问题。与EG（Exponential Gradient）策略仅利用单期价格信息估计价格趋势不同,本文将利用多期价格信息估计价格趋势,以提高在线策略的性能。首先,基于多期价格数据,利用L₁-中位数估计得到预期价格趋势。然后,通过期望效用最大化,提出一个新的具有线型时间复杂度的在线策略,EGLM（Exponential Gradient via L₁-Median）。并通过相对熵函数定义资产权重向量的距离,进而证明了EGLM策略具有泛证券投资组合性质。最后,利用国内外6个证券市场的历史数据进行实证分析,结果表明相较于UP（Universal Portfolio）策略和EG策略,EGLM策略有更好的竞争性能。     

On generalised estimating equations for vector regression

Generalised estimating equations (GEE) for regression problems with vector‐valued responses are examined. When the response vectors are of mixed type (e.g. continuous–binary response pairs), the GEE approach is a semiparametric alternative to full‐likelihood copula methods, and is closely related to Prentice & Zhao's mean‐covariance estimation equations approach. When the response vectors are of the same type (e.g. measurements on left and right eyes), the GEE approach can be viewed as a ‘plug‐in’ to existing methods, such as the vglm function from the state‐of‐the‐art VGAM package in R. In either scenario, the GEE approach offers asymptotically correct inferences on model parameters regardless of whether the working variance–covariance model is correctly or incorrectly specified. The finite‐sample performance of the method is assessed using simulation studies based on a burn injury dataset and a sorbinil eye trial dataset. The method is applied to data analysis examples using the same two datasets, as well as to a trivariate binary dataset on three plant species in the Hunua ranges of Auckland.