Joint impact of multiple observations on a subset of variables in multiple linear regression

In multiple linear regression analysis, each observation affects the fitted regression equation differently and has varying influences on the regression coefficients of the different variables. Chatterjee & Hadi (1988) have proposed some measures such as DSSE_ij (Impact on Residual Sum of Squares of simultaneously omitting the ith observation and the jth variable), F_j (Partial F-test for the jth variable) and F_j(i) (Partial F-test for the jth variable omitting the ith observation) to show the joint impact and the interrelationship that exists among a variable and an observation. In this paper we have proposed more extended form of those measures DSSE_IJ, F_J and F_J(I) to deal with the interrelationships that exist among the multiple observations and a subset of variables by monitoring the effects of the simultaneous omission of multiple variables and multiple observations.     

读《永生医院》，想象“永生”——从“写什么”说到“生生”

文章以郝景芳在《永生医院》中遭遇到的"永生"问题为切入点,在中西方生命哲学的大背景下,对当代科技手段制造出来的"新人"所带来的文化冲击和个体生命的意义危机进行了深入的思考。作者从中国传统的"生生"哲学出发,深入剖析了以技艺人的工作经验为基础的古希腊"制造"哲学借助于当代科技手段造成的生命哲学危机,指出"永生"不是生命的最高目标,唯有在变动不息的"生生"之中,才有生命的真实意义。     

Implementing partial least squares

Partial least squares (PLS) regression has been proposed as an alternative regression technique to more traditional approaches such as principal components regression and ridge regression. A number of algorithms have appeared in the literature which have been shown to be equivalent. Someone wishing to implement PLS regression in a programming language or within a statistical package must choose which algorithm to use. We investigate the implementation of univariate PLS algorithms within FORTRAN and the Matlab (1993) and Splus (1992) environments, comparing theoretical measures of execution speed based on flop counts with their observed execution times. We also comment on the ease with which the algorithms may be implemented in the different environments. Finally, we investigate the merits of using the orthogonal invariance of PLS regression to improve the algorithms.     

小麦新品种“绵阳26”主要性状与产量的关系

对45个试验点的资料分析,多抗、丰产、优质、广适小麦新品种绵阳26的主要性状有效穗x1、穗粒数x2和千粒x3、单穗重x4与产量y的回归方程为：y＝－614．8425＋9.8683x1＋7.3223x2＋10．5315x3＋22．5748x4。经偏回归和偏相关分析,产量构成因素中,千粒重、有效穗对绵阳26产量的贡献和影响最大（b'3＝1．7435,b'1＝1．5372,R3y.＝0．7983,R1y＝0．6991）。在现有产量的基础上稳定千粒重,主攻穗数和穗粒数,是发挥绵阳26高产潜力的决定因素。     

Spatial variation in risk of disease: a nonparametric binary regression approach

A common problem in environmental epidemiology is the estimation and mapping of spatial variation in disease risk. In this paper we analyse data from the Walsall District Health Authority, UK, concerning the spatial distributions of cancer cases compared with controls sampled from the population register. We formulate the risk estimation problem as a nonparametric binary regression problem and consider two different methods of estimation. The first uses a standard kernel method with a cross-validation criterion for choosing the associated bandwidth parameter. The second uses the framework of the generalized additive model (GAM) which has the advantage that it can allow for additional explanatory variables, but is computationally more demanding. For the Walsall data, we obtain similar results using either the kernel method with controls stratified by age and sex to match the age–sex distribution of the cases or the GAM method with random controls but incorporating age and sex as additional explanatory variables. For cancers of the lung or stomach, the analysis shows highly statistically significant spatial variation in risk. For the less common cancers of the pancreas, the spatial variation in risk is not statistically significant.     

Application of Markov chain Monte Carlo methods to modelling birth prevalence of Down syndrome

Data collected before the routine application of prenatal screening are of unique value in estimating the natural live-birth prevalence of Down syndrome. However, much of these data are from births from over 20 years ago and they are of uncertain quality. In particular, they are subject to varying degrees of underascertainment. Published approaches have used ad hoc corrections to deal with this problem or have been restricted to data sets in which ascertainment is assumed to be complete. In this paper we adopt a Bayesian approach to modelling ascertainment and live-birth prevalence. We consider three prior specifications concerning ascertainment and compare predicted maternal-age-specific prevalence under these three different prior specifications. The computations are carried out by using Markov chain Monte Carlo methods in which model parameters and missing data are sampled.     

半导体激光器的光学准直

对半导体激光器进行光学准直是空间光通信系统必须进行的重要工作。文中简述了准直通常使用的方法,测试了使用单透镜对一种３５ｍＷ半导体激光器的准直结果,准直效率约为６０％,准直后的发射角为０４～０７５ｍｒａｄ。     

Evaluating a private foundation's health program

Public policy decisions in health are increasingly difficult and expensive. Although there will never be enough information available, private foundations can help to bridge the most important gaps in knowledge. Larger foundations may also wish to respond to those who doubt the value of foundation activities. This article reviews the experiences over the past eight years of The Robert Wood Johnson Foundation in employing evaluation and related social research procedures in the planning and implementation of a major philanthropic effort to improve the health and medical care of Americans. Discussed are the still evolving Foundation evaluation framework, the unanticipated problems in undertaking specific evaluations, and the substantive findings of some of the studies.     

Network analysis in evaluation: some words of caution

Network analysis, a methodology derived from general systems' theory, can be utilized as a community mental health administrative-evaluation procedure. Evaluation parameters derived from analysis of patient data as they “flow” through a network of agency services, provide measures of systemic functioning. These parameters include “longest paths” and various ratio relationships as evaluation measures of service delivery. The limitations of network analysis are examined by means of conceptual analyses, and phenomena that emerged from research experience. The necessity for both quantitative and qualitative data to ensure a meaningful evaluation of mental health services is explained. Conclusions about the value of the network analysis approach are considered.     

基于GRPLS 回归的 中国经济增长影响因素分析

构造一种新的方法———岭- 偏最小二乘回归方法(它既有效消除了因素变量之间的多 重共线性,又克服了传统方法的不足,且使模型更加稳健,具有更强的预测和分析能力) ;并运 用广义岭- 偏最小二乘回归方法分析了我国经济增长的影响因素,为我国制订持续、快速增长 的经济政策提供了有益的参考.