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91.
The effects of non-normality on type-I and type-II errors in a one-way random model are investigated for moderate departures from normality. It is found that the probabilities of both errors are more sensitive to the kurtosis of between group effects than that of within group effects.  相似文献   
92.
Rivest Wells (2001) showed that in situations where the dependence between a lifetime and a censoring variable can be modeled by a given Archimedean copula, the copula‐graphic estimator of Zheng Klein (1995) has an explicit form. The authors extend this work to the fixed design regression case. They show that the copula‐graphic estimator then has an asymptotic representation and a Gaussian limit. They also assess the influence of a misspecified copula function on the performance of the estimator. Their developments are illustrated with data on the survival of the Atlantic halibut.  相似文献   
93.
Incomplete covariate data is a common occurrence in many studies in which the outcome is survival time. With generalized linear models, when the missing covariates are categorical, a useful technique for obtaining parameter estimates is the EM by the method of weights proposed in Ibrahim (1990). In this article, we extend the EM by the method of weights to survival outcomes whose distributions may not fall in the class of generalized linear models. This method requires the estimation of the parameters of the distribution of the covariates. We present a clinical trials example with five covariates, four of which have some missing values.  相似文献   
94.
Received: August 14, 2000; revised version: April 23, 2001  相似文献   
95.
Markers, which are prognostic longitudinal variables, can be used to replace some of the information lost due to right censoring. They may also be used to remove or reduce bias due to informative censoring. In this paper, the authors propose novel methods for using markers to increase the efficiency of log‐rank tests and hazard ratio estimation, as well as parametric estimation. They propose a «plug‐in» methodology that consists of writing the test statistic or estimate of interest as a functional of Kaplan–Meier estimators. The latter are then replaced by an efficient estimator of the survival curve that incorporates information from markers. Using simulations, the authors show that the resulting estimators and tests can be up to 30% more efficient than the usual procedures, provided that the marker is highly prognostic and that the frequency of censoring is high.  相似文献   
96.
Abstract: In 2003, the total fertility rate in Japan was 1.29. According to many predictions, if the current rate continues, the labor shortage will become critical. The Economic and Fiscal Policy White Paper, edited by the Cabinet Office ( Naikakuhu, 2003a ), stated “If we attempt to fill the lack by accepting immigrants in order to maintain the population of productive workers, we will need to accept 640 000 immigrants every year until 2050. It is necessary to make our country more attractive for foreign workers”. However, it is unlikely that more than 30 million immigrants will choose to live in Japan unless efforts are made to abolish xenophobia and to make qualitative changes that will change Japanese society so that it is more open to co‐existence. Moreover, Japan is not the only country that must worry about future declines in the work force and other countries will most likely start to attract foreign workers earlier than Japan ( Naikakuhu, 2003b ).  相似文献   
97.
This article shows how to construct a likelihood for a general class of censoring problems. This likelihood is proven to be valid, i.e. its maximizer is consistent and the respective root-n estimator is asymptotically efficient and normally distributed under regularity conditions. The method generalizes ordinary maximum likelihood estimation as well as several standard estimators for censoring problems (e.g. tobit type I-tobit type V).  相似文献   
98.
Necessary and sufficient conditions for weak and strong convergence are derived for the weighted version of a general process under random censoring. To be more explicit, this means that for this process complete analogues are obtained of the Chibisov-O'Reilly theorem, the Lai-Wellner Glivenko-Cantelli theorem, and the James law of the iterated logarithm for the empirical process. The process contains as special cases the so-called basic martingale, the empirical cumulative hazard process, and the product-limit process. As a tool we derive a Kiefer-process-type approximation of our process, which may be of independent interest.  相似文献   
99.
以5个两系杂交稻及相应的两用系为材料,在自然温度条件下进行长日(15:00小时)和短日(10:00小时)处理,结果再次表明,两用核不育系的不育性属隐性核遗传,在杂种F1代不表达。两用系的可恢性及父本的恢复力、亲和力是影响两系杂交稻结实率的主要因素。  相似文献   
100.
The properties of robust M-estimators with type II censored failure time data are considered. The optimal members within two classes of ψ-functions are characterized. The first optimality result is the censored data analogue of the optimality result described in Hampel et al. (1986); the estimators corresponding to the optimal members within this class are referred to as the optimal robust estimators. The second result pertains to a restricted class of ψ-functions which is the analogue of the class of ψ-functions considered in James (1986) for randomly censored data; the estimators corresponding to the optimal members within this restricted class are referred to as the optimal James-type estimators. We examine the usefulness of the two classes of ψ-functions and find that the breakdown point and efficiency of the optimal James-type estimators compare favourably with those of the corresponding optimal robust estimators. From the computational point of view, the optimal James-type ψ-functions are readily obtainable from the optimal ψ-functions in the uncensored case. The ψ-functions for the optimal robust estimators require a separate algorithm which is provided. A data set illustrates the optimal robust estimators for the parameters of the extreme value distribution.  相似文献   
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