An equivalence test for comparing DNA sequences

The practice of sequence alignment is constantly oscillating between the risk of overlooking important structure and that of discovering any arbitrarily defined kind of structure anywhere. On the other hand, the use of a condensed consensus sequence may lead to a substantial loss in valuable information. While adopting a Mahalanobis‐type index we allow for a certain degree of uncertainty in the measurements. This uncertainty may be caused by inaccurate measurements or ambiguity. In this paper, we test the similarity between DNA sequences within the framework of equivalence testing, accounting for both variances and covariances between frequencies of nucleotides. Statistical methods for testing equivalence were first developed in the context of pharmacokinetics and later extended to the field of clinical trials. Nowadays, (bio)equivalence tests seem to be less frequently used outside the drug testing field, including statistical genetics. Copyright © 2005 John Wiley & Sons, Ltd.     

教師應該允許有多大的自主性(英文)

本文涉及教師自主性的問题,包括教師應否有自主性,應有多大的自主性。作者探討了教師自主性在课堂及學習過程中發揮的正面影響。教師的自主性與他的满足感乃至流動性都有直接的關係。本文還對學校行政人員在教師自主性上扮演的角色也作了回顧,闡明了行政人员經常出於各種考慮傾向於限制教師的自主性。此外,也探討了規範化测試對於教師自主性的影響。     

在江苏开展艾滋病自愿咨询检测(VCT)服务的思考

艾滋病自愿咨询检测(voluntary counseling and testing,VCT),是指人们在经过咨询以后能够对于是否做艾滋病检测做出自我选择的过程。开展VCT服务是进入艾滋病预防、治疗、心理社会支持和关怀工作的切入点和枢纽。在预防HIV的传播,对患者提供情感支持,减少对HIV感染者的歧视以及为感染者提供合适的治疗转诊服务等方面都具有重要意义。VCT服务在江苏的试点已显示出大众对此服务的强烈需求。如果当前能在全省广泛开展艾滋病自愿咨询检测服务,尽早发现感染者,并有针对性地开展各项干预措施,将对江苏省艾滋病防治产生积极作用。     

全自动热泵用四通电磁换向阀寿命试验台的研制

对JB/T7230 94热泵用四通换向阀进行了研究分析,用实际的制冷工质代替氮气,模拟四通换向阀的实际工作环境,测试四通换向阀的使用寿命.设计建造了一套全自动四通换向阀寿命测试系统,研制了试验环境空气处理系统,编制了工况参数控制和电气系统设计及软件程序,并进行了四通换向阀的寿命测试试验.试验结果表明,用制冷工质模拟实际工作条件能够准确测试四通换向阀的寿命.     

青少年犯罪社区矫正工作个案报告

社区矫正是一种与监禁矫正相对的行刑方式,当前青少年犯罪社区矫近日益引起社会各界的关注.A是安徽省某县社区服刑人员.通过对A的个性心理特征、心理健康状况以及家庭状况的分析,社区矫正工作者对A进行了4个月的社区矫正,A从思想到行为各方面都有很大进步,但仍然存在一些问题.     

“泛珠三角”九省区消费结构的实证研究——基于Panel data下的数量分析

通过对"泛珠三角"九省区内的消费现状、影响因素及其产生原因的初步研究,构建了两个计量经济学模型来做进一步的实证分析:其一是利用单位根理论检验区域内消费支出是否具有长期均衡关系;其二是利用面板数据模型估计区域内消费结构的差异,期望能以此促进整个"泛珠三角"区域的经济均衡与可持续发展。     

Hypotheses Testing: Poisson Versus Self-exciting

Abstract.  We consider the problem of hypotheses testing with the basic simple hypothesis: observed sequence of points corresponds to the stationary Poisson process with known intensity. The alternatives are stationary self-exciting point processes. We consider one-sided parametric and one-sided non-parametric composite alternatives and construct locally asymptotically uniformly most powerful tests. The results of numerical simulations of the tests are presented.     

用不动点定理研究方程解的存在性

介绍常用的不动点定理,并给出它在方程中有关解的存在问题的应用实例.     

英语阅读能力及其测试:理论与实践

英语阅读是英语教学的重要环节。如何对阅读的教学进行检测以提高英语阅读的效率一直是应用语言学界及教育主管部门探索的问题。认识阅读的机理,了解语篇与读者阅读过程中的互动,有助于阅读能力检测的设计,进而确定检测的内容与形式。通过对某大学外语专业学生的阅读测试结果的各项指标(信度、效度、区分度)进行分析,可以看到,要设计出一套能准确反映出学生的阅读能力的测试题目绝非易事。需要进一步的理论探索与实践,才能不断完善。     

CASE-DELETION DIAGNOSTICS FOR TEST STATISTICS IN MULTIVARIATE REGRESSION

Influence measures in multivariate regression analysis have been widely developed, especially through use of the case-deletion approach. However, there seem to be few accounts of the influence of observations on test statistics in hypothesis testing. This paper examines four common multivariate tests, namely the Wilks' ratio, Lawley-Hotelling trace, Pillai's trace and Roy's greatest root for testing a general linear hypothesis of the regression coefficients in multivariate regression. The influence of observations is measured using the case-deletion approach. The proposed diagnostic measures, except that of Roy's greatest root, can be expressed in terms of statistics without involving the actual deletion of observations. An illustrative example is given with satisfactory results.