Multivariate bandwidth selection for local linear regression

The existence and properties of optimal bandwidths for multivariate local linear regression are established, using either a scalar bandwidth for all regressors or a diagonal bandwidth vector that has a different bandwidth for each regressor. Both involve functionals of the derivatives of the unknown multivariate regression function. Estimating these functionals is difficult primarily because they contain multivariate derivatives. In this paper, an estimator of the multivariate second derivative is obtained via local cubic regression with most cross-terms left out. This estimator has the optimal rate of convergence but is simpler and uses much less computing time than the full local estimator. Using this as a pilot estimator, we obtain plug-in formulae for the optimal bandwidth, both scalar and diagonal, for multivariate local linear regression. As a simpler alternative, we also provide rule-of-thumb bandwidth selectors. All these bandwidths have satisfactory performance in our simulation study.     

Estimation with unbalanced panel data having covariate measurement error

Panel data with covariate measurement error appear frequently in various studies. Due to the sampling design and/or missing data, panel data are often unbalanced in the sense that panels have different sizes. For balanced panel data (i.e., panels having the same size), there exists a generalized method of moments (GMM) approach for adjusting covariate measurement error, which does not require additional validation data. This paper extends the GMM approach of adjusting covariate measurement error to unbalanced panel data. Two health related longitudinal surveys are used to illustrate the implementation of the proposed method.     

Optimal designs for tumor regrowth models

Most growth curves can only be used to model the tumor growth under no intervention. To model the growth curves for treated tumor, both the growth delay due to the treatment and the regrowth of the tumor after the treatment need to be taken into account. In this paper, we consider two tumor regrowth models and determine the locally D- and c-optimal designs for these models. We then show that the locally D- and c-optimal designs are minimally supported. We also consider two equally spaced designs as alternative designs and evaluate their efficiencies.     

A Sensitivity Analysis Approach for Some Deterministic Multi-Criteria Decision-Making Methods*

Often, data in multi-criteria decision making (MCDM) problems are imprecise and changeable. Therefore, an important step in many applications of MCDM is to perform a sensitivity analysis on the input data. This paper presents a methodology for performing a sensitivity analysis on the weights on the decision criteria and the performance values of the alternatives expressed in terms of the decision criteria. The proposed methodology is demonstrated on three widely used decision methods. These methods are the weighted sum model (WSM), the weighted product model (WPM), and the analytic hierarchy process (AHP). This paper formalizes a number of important issues on sensitivity analysis and derives some critical theoretical results. Also, a number of illustrative examples and computational experiments further illustrate the application of the proposed methodology.     

Almost Sure Convergence of Weighted Sums for Negatively Associated Random Variables

In this article, let {X₁, …, X_n} be a sequence of negatively associated random variables and {a_ni, 1 ? i ? n, n ? 1} be a triangular array of constants. Several almost sure convergence theorems for the weighted sums ∑ⁿ_{i = 1}a_niX_i are established.     

A weighted likelihood ratio test-based chart for monitoring process mean and variability

In this paper, a new single exponentially weighted moving average (EWMA) control chart based on the weighted likelihood ratio test, referred to as the WLRT chart, is proposed for the problem of monitoring the mean and variance of a normally distributed process variable. It is easy to design, fast to compute, and quite effective for diverse cases including the detection of the decrease in variability and individual observation case. The optimal parameters that can be used as a design aid in selecting specific parameter values based on the average run length (ARL) and the sample size are provided. The in-control (IC) and out-of-control (OC) performance properties of the new chart are compared with some other existing EWMA-type charts. Our simulation results show that the IC run length distribution of the proposed chart is similar to that of a geometric distribution, and it provides quite a robust and satisfactory overall performance for detecting a wide range of shifts in the process mean and/or variability.     

Likelihood inference based on EM algorithm for the destructive length-biased Poisson cure rate model with Weibull lifetime

In this article, we consider the destructive length-biased Poisson cure rate model, proposed by Rodrigues et al., that presents a realistic and interesting interpretation of the biological mechanism for the recurrence of tumor in a competing causes scenario. Assuming the lifetime to follow the Weibull distribution and censoring mechanism to be non-informative, the necessary steps of the EM algorithm for the determination of the MLEs of the model parameters are developed here based on right censored data. The standard errors of the MLEs are obtained by inverting the observed information matrix. A simulation study is then carried out to examine the method of inference developed here. Finally, the proposed methodology is illustrated with a real melanoma dataset.     

Efficient circular neighbour designs for spatial interference model

We consider circular block designs for field-trials when there are two-sided spatial interference between neighbouring plots of the same blocks. The parameter of interest is total effects that is the sum of direct effect of treatment and neighbour effects, which correspond to the use of a single treatment in the whole field. We determine universally optimal approximate designs. When the number of blocks may be large, we propose efficient exact designs generated by a single sequence of treatment. We also give efficiency factors of the usual binary block neighbour balanced designs which can be used when the number of blocks is small.     

Addition of runs to an s-level supersaturated design

The purpose of the present work is to extend the work of Gupta et al. (2010) to s  -level column balanced supersaturated designs. Addition of runs to an existing E(χ²)-optimal$E({\chi }^2)\mathrm{-}\mathrm{optimal}$ supersaturated design and to study the optimality of the resulting design is an important issue. This paper considers the study of the optimality of the resulting design. A lower bound to E(χ²)$E({\chi }^2)$ has been obtained for the extended supersaturated designs. Some examples and a small catalogue of E(χ²)-optimal$E({\chi }^2)\mathrm{-}\mathrm{optimal}$ supersaturated designs are also presented.