Semiparametric Time-Varying Coefficients Regression Model for Longitudinal Data

Abstract.  In this paper, we consider a semiparametric time-varying coefficients regression model where the influences of some covariates vary non-parametrically with time while the effects of the remaining covariates follow certain parametric functions of time. The weighted least squares type estimators for the unknown parameters of the parametric coefficient functions as well as the estimators for the non-parametric coefficient functions are developed. We show that the kernel smoothing that avoids modelling of the sampling times is asymptotically more efficient than a single nearest neighbour smoothing that depends on the estimation of the sampling model. The asymptotic optimal bandwidth is also derived. A hypothesis testing procedure is proposed to test whether some covariate effects follow certain parametric forms. Simulation studies are conducted to compare the finite sample performances of the kernel neighbourhood smoothing and the single nearest neighbour smoothing and to check the empirical sizes and powers of the proposed testing procedures. An application to a data set from an AIDS clinical trial study is provided for illustration.     

Random Weighted Bootstrap Method for Recurrent Events with Informative Censoring

Using the data from the AIDS Link to Intravenous Experiences cohort study as an example, an informative censoring model was used to characterize the repeated hospitalization process of a group of patients. Under the informative censoring assumption, the estimators of the baseline rate function and the regression parameters were shown to be related to a latent variable. Hence, it becomes impractical to directly estimate the unknown quantities in the moments of the estimators for the bandwidth selection of a smoothing estimator and the construction of confidence intervals, which are respectively based on the asymptotic mean squared errors and the asymptotic distributions of the estimators. To overcome these difficulties, we develop a random weighted bootstrap procedure to select appropriate bandwidths and to construct approximated confidence intervals. One can see that our method is simple and faster to implement from a practical point of view, and is at least as accurate as other bootstrap methods. In this article, it is shown that the proposed method is useful through the performance of a Monte Carlo simulation. An application of our procedure is also illustrated by a recurrent event sample of intravenous drug users for inpatient cares over time.     

Variable Bandwidths for Nonparametric Hazard Rate Estimation

A smoothing parameter inversely proportional to the square root of the true density is known to produce kernel estimates of the density having faster bias rate of convergence. We show that in the case of kernel-based nonparametric hazard rate estimation, a smoothing parameter inversely proportional to the square root of the true hazard rate leads to a mean square error rate of order n ^?8/9, an improvement over the standard second order kernel. An adaptive version of such a procedure is considered and analyzed.     

Selection of bandwidth for kernel regression

ABSTRACT

The most important factor in kernel regression is a choice of a bandwidth. Considerable attention has been paid to extension the idea of an iterative method known for a kernel density estimate to kernel regression. Data-driven selectors of the bandwidth for kernel regression are considered. The proposed method is based on an optimally balanced relation between the integrated variance and the integrated square bias. This approach leads to an iterative quadratically convergent process. The analysis of statistical properties shows the rationale of the proposed method. In order to see statistical properties of this method the consistency is determined. The utility of the method is illustrated through a simulation study and real data applications.     

A plug-in technique in nonparametric regression with dependence

The problem addressed is that of smoothing parameter selection in kernel nonparametric regression in the fixed design regression model with dependent noise. An asymptotic expression of the optimum bandwidth parameter has been obtained in recent studies, where this takes the form h = C ₀ n ^?1/5. This paper proposes to use a plug-in methodology, in order to obtain an optimum estimation of the bandwidth parameter, through preliminary estimation of the unknown value of C ₀.     

Asymptotic Behavior of the Hazard Rate Kernel Estimator Under Truncated and Censored Data

In this article, we give the asymptotic mean integrated squared error and the mean squared error for the kernel estimator of the hazard rate from truncated and censored data. Martingale techniques and combinatory calculus are used to obtain these results. A probability bound and the optimal bandwidth choice are also given.     

Beta-Bernstein Smoothing for Regression Curves with Compact Support

ABSTRACT. The problem of boundary bias is associated with kernel estimation for regression curves with compact support. This paper proposes a simple and uni(r)ed approach for remedying boundary bias in non-parametric regression, without dividing the compact support into interior and boundary areas and without applying explicitly different smoothing treatments separately. The approach uses the beta family of density functions as kernels. The shapes of the kernels vary according to the position where the curve estimate is made. Theyare symmetric at the middle of the support interval, and become more and more asymmetric nearer the boundary points. The kernels never put any weight outside the data support interval, and thus avoid boundary bias. The method is a generalization of classical Bernstein polynomials, one of the earliest methods of statistical smoothing. The proposed estimator has optimal mean integrated squared error at an order of magnitude n ^−4/5, equivalent to that of standard kernel estimators when the curve has an unbounded support.     

Simple and effective number-of-bins circumference selectors for a histogram

Two very effective data-based procedures which are simple and fast to compute are proposed for selecting the number of bins in a histogram. The idea is to choose the number of bins that minimizes the circumference (or a bootstrap estimate of the expected circumference) of the frequency histogram. Contrary to most rules derived in the literature, our method is therefore not dependent on precise asymptotic analyses. It is shown by means of an extensive Monte-Carlo study that our selectors perform well in comparison with recently suggested selectors in the literature, for a wide range of density functions and sample sizes. The behaviour of one of the proposed rules is also illustrated on real data sets.     

Multivariate bandwidth selection for local linear regression

The existence and properties of optimal bandwidths for multivariate local linear regression are established, using either a scalar bandwidth for all regressors or a diagonal bandwidth vector that has a different bandwidth for each regressor. Both involve functionals of the derivatives of the unknown multivariate regression function. Estimating these functionals is difficult primarily because they contain multivariate derivatives. In this paper, an estimator of the multivariate second derivative is obtained via local cubic regression with most cross-terms left out. This estimator has the optimal rate of convergence but is simpler and uses much less computing time than the full local estimator. Using this as a pilot estimator, we obtain plug-in formulae for the optimal bandwidth, both scalar and diagonal, for multivariate local linear regression. As a simpler alternative, we also provide rule-of-thumb bandwidth selectors. All these bandwidths have satisfactory performance in our simulation study.     

Adaptive normal reference bandwidth based on quantile for kernel density estimation

Bandwidth selection is an important problem of kernel density estimation. Traditional simple and quick bandwidth selectors usually oversmooth the density estimate. Existing sophisticated selectors usually have computational difficulties and occasionally do not exist. Besides, they may not be robust against outliers in the sample data, and some are highly variable, tending to undersmooth the density. In this paper, a highly robust simple and quick bandwidth selector is proposed, which adapts to different types of densities.