Validation of a Method for Estimating Long-Term Exposures Based on Short-Term Measurements

A method for estimating long-term exposures from short-term measurements is validated using data from a recent EPA study of exposure to fine particles. The method was developed a decade ago but long-term exposure data to validate it did not exist until recently. In this article, exposure data from repeated visits to 37 persons over 1 year (up to 28 measurements per person) are used to test the model. Both fine particle mass and elemental concentrations measured indoors, outdoors, and on the person are examined. To provide the most stringent test of the method, only two single-day distributions are randomly selected for each element to predict the long-term distributions. The precision of the method in estimating the long-term geometric mean and geometric standard deviation appears to be of the order of 10%, with no apparent bias. The precision in estimating the 99 th percentile ranges from 19% to 48%, again without obvious bias. The precision can be improved by selecting a number of pairs of single-day distributions instead of just one pair. Occasionally, the method fails to provide an estimate for the long-term distribution. In that case, a repeat of the random selection procedure can provide an estimate. Although the method assumes a log-normal distribution, most of the distributions tested failed the chi-square test for log-normality. Therefore, the method appears suitable for application to distributions that depart from log-normality.     

Parametric estimation under a class of multivariate distributions

In this paper the parameters of some members of a class of multivariate distributions, which was constructed by AL-Hussaini and Ateya (2003), are estimated by using the maximum likelihood and Bayes methods.     

UMVU estimation of the reliability function of the generalized life distributions

The problems of estimating the reliability function and P=P_rX > Y are considered for the generalized life distributions. Uniformly minimum variance unbiased estimators (UMVUES) of the powers of the parameter involved in the probabilistic model and the probability density function (pdf) at a specified point are derived. The UMVUE of the pdf is utilized to obtain the UMVUE of the reliability function and ‘P’. Our method of obtaining these estimators is quite simple than the traditional approaches. A theoretical method of studying the behaviour of the hazard-rate is provided.     

Diagonalization matrix and its application in distribution theory

Some matrix representations of diverse diagonal arrays are studied in this work; the results allow new definitions of classes of elliptical distributions indexed by kernels mixing Hadamard and usual products. A number of applications are derived in the setting of prior densities from the Bayesian multivariate regression model and families of non-elliptical distributions, such as the matrix multivariate generalized Birnbaum–Saunders density. The philosophy of the research about matrix representations of quadratic and inverse quadratic forms can be extended as a methodology for exploring possible new applications in non-standard distributions, matrix transformations and inference.     

Multivariate generalized linear mixed models with random intercepts to analyze cardiovascular risk markers in type-1 diabetic patients

Statistical approaches tailored to analyzing longitudinal data that have multiple outcomes with different distributions are scarce. This paucity is due to the non-availability of multivariate distributions that jointly model outcomes with different distributions other than the multivariate normal. A plethora of research has been done on the specific combination of binary-Gaussian bivariate outcomes but a more general approach that allows other mixtures of distributions for multiple longitudinal outcomes has not been thoroughly demonstrated and examined. Here, we study a multivariate generalized linear mixed models approach that jointly models multiple longitudinal outcomes with different combinations of distributions and incorporates the correlations between the various outcomes through separate yet correlated random intercepts. Every outcome is linked to the set of covariates through a proper link function that allows the incorporation and joint modeling of different distributions. A novel application was demonstrated on a cohort study of Type-1 diabetic patients to jointly model a mix of longitudinal cardiovascular outcomes and to explore for the first time the effect of glycemic control treatment, plasma prekallikrein biomarker, gender and age on cardiovascular risk factors collectively.     

Effect of length-biased sampling on the modeling error

In statistical data analysis, the choice of an appropriate model is a very important factor. An inappropriate model leads to a different kind of error in the analysis. This error has been called by C. R. Rao as type III error or modeling error as opposed to type I and type II errors in statistical inference.In This paper we Study the relative errors in Incurred by Erroneously Assuming the Distribution of the Family Size N as P(n) While in fact it is the Length-biased (Weighted) Version of P(n).An Analytical Expression for the Relative Error,When the Distribution of N Belongs to the Class of Modified Power Series Distributions, is Derived. More Specifically, the Effect of length-biasing on the Relative Error is Investigated, When N Follows a Generalized Poisson Distribution. These Results are Compared With the Case When N Follows a Poisson Distribution.     

Estimation of the parameters of a general student’s t distribution

We have observations for a t distribution with unknown mean, variance, and degrees of freedom, each of which we wish to estimate. The major problem lies in the estimate of the degrees of freedom. We show that a relatively efficient yet very simple estimator is a given function of the ratio of percentile estimates. We derive the appropriate estimator, provide equations for transformation and standard errors, contrast this with other estimators, and give examples.     

A bayesian analysis of the multinomial model for a dichotomous response with nonrespondents

This paper studies the mu1tinomial model 2x2 contingency table data with some cell counts missing .Various hypotheses of interest including row-column independence are tested by using Bayes factors which represent the ratio of the posterior odds to the prior odds for the null hypothesis. The Dirichlet-Beta family of prior distributions is considered for the multinomial parameters cond itional on the complement of the null hypothesis. The Bayes factor for the incomplete data is a mixture of the Bayes factors for different possibilities for the full data.     

Multiple linear regression model with stochastic design variables

In a simple multiple linear regression model, the design variables have traditionally been assumed to be non-stochastic. In numerous real-life situations, however, they are stochastic and non-normal. Estimators of parameters applicable to such situations are developed. It is shown that these estimators are efficient and robust. A real-life example is given.