Estimation of a discriminant function from a mixture of two inverse Weibull distributions

The classification of a random variable based on a mixture can be meaningfully discussed only if the class of all finite mixtures is identifiable. In this paper, we find the maximum-likelihood estimates of the parameters of the mixture of two inverse Weibull distributions by using classified and unclassified observations. Next, we estimate the nonlinear discriminant function of the underlying model. Also, we calculate the total probabilities of misclassification as well as the percentage bias. In addition, we investigate the performance of all results through a series of simulation experiments by means of relative efficiencies. Finally, we analyse some simulated and real data sets through the findings of the paper.     

Case–control genome-wide joint association study using semiparametric empirical model and approximate Bayes factor

We propose a semiparametric approach for the analysis of case–control genome-wide association study. Parametric components are used to model both the conditional distribution of the case status given the covariates and the distribution of genotype counts, whereas the distribution of the covariates are modelled nonparametrically. This yields a direct and joint modelling of the case status, covariates and genotype counts, and gives a better understanding of the disease mechanism and results in more reliable conclusions. Side information, such as the disease prevalence, can be conveniently incorporated into the model by an empirical likelihood approach and leads to more efficient estimates and a powerful test in the detection of disease-associated SNPs. Profiling is used to eliminate a nuisance nonparametric component, and the resulting profile empirical likelihood estimates are shown to be consistent and asymptotically normal. For the hypothesis test on disease association, we apply the approximate Bayes factor (ABF) which is computationally simple and most desirable in genome-wide association studies where hundreds of thousands to a million genetic markers are tested. We treat the approximate Bayes factor as a hybrid Bayes factor which replaces the full data by the maximum likelihood estimates of the parameters of interest in the full model and derive it under a general setting. The deviation from Hardy–Weinberg Equilibrium (HWE) is also taken into account and the ABF for HWE using cases is shown to provide evidence of association between a disease and a genetic marker. Simulation studies and an application are further provided to illustrate the utility of the proposed methodology.     

On the moment generating functions for integer valued random variables

Abstract

In this note, we give explicit expressions of moment generating functions for integer valued random variables in both univariate and multivariate cases, which extend the results obtained by Nadarajah and Mitov [Communications in Statistics–Theory and Methods, 32, 2003, 47–60] and more recently by Chakraborti, Jardim and Epprecht [The American Statistician, 2017], Kwong and Nadarajah [Communications in Statistics–Theory and Methods, 2017]. Some examples are also discussed.     

Estimating population size with truncated sampling

Let X₁, X₂,…,X_n be independent, indentically distributed random variables with density f(x,θ) with respect to a σ-finite measure μ. Let R be a measurable set in the sample space X. The value of X is observable if X ? (X?R) and not otherwise. The number J of observable X’s is binomial, N, Q, Q = 1?P(X ? R). On the basis of J observations, it is desired to estimate N and θ. Estimators considered are conditional and unconditional maximum likelihood and modified maximum likelihood using a prior weight function to modify the likelihood before maximizing. Asymptotic expansions are developed for the [Ncirc]’s of the form [Ncirc] = N + α√N + β + o_p(1), where α and β are random variables. All estimators have the same α, which has mean 0, variance σ² (a function of θ) and is asymptotically normal. Hence all are asymptotically equivalent by the usual limit distributional theory. The β’s differ and Eβ can be considered an “asymptotic bias”. Formulas are developed to compare the asymptotic biases of the various estimators. For a scale parameter family of absolutely continuous distributions with X = (0,∞) and R = (T,∞), special formuli are developed and a best estimator is found.     

Classical estimation of hazard rate and mean residual life functions of Pareto distribution

Abstract

In this paper we find the maximum likelihood estimates (MLEs) of hazard rate and mean residual life functions (MRLF) of Pareto distribution, their asymptotic non degenerate distribution, exact distribution and moments. We also discuss the uniformly minimum variance unbiased estimate (UMVUE) of hazard rate function and MRLF. Finally, two numerical examples with simulated data and real data set, are presented to illustrate the proposed estimates.     

Mathematical forms of the distribution of the product of two normal variables

This paper finds the mathematical forms of the distribution of the product where x and x follow a bivariate normal distribution In this paper the distribution when PT0 is expressed as an integral, a new, fundamental result. From this general form, six different cases can be distinguished depending on what is known about the parameters and p. The special cases are Aroian $year:1959 and (6) Additionally, we prove that if and as the distribution of the product approaches the Type III distribution. When p=0# Aroian $year:1959 and Aroian and Meeker $year:1977, give tables for various values of 6., 6 . The results in this paper will be used to provide brief tables for p^O in a separate paper     

On a life testing problem involving the two parameter exponential distribution

For a hypothesis testing problem involving the location and scale parameters of an exponential distribution, Perng (1977) proposed a test procedure based on the first r out of n observed failure times. In this paper the likelihood ratio test is determined, critical values are provided and the asymptotic null distribution is determined. An alternate test based on an F statistic is also proposed and the critical regions and power functions of the procedures are compared.     

How non-normality affects the quadratic discriminant function

The quadratic discriminant function is commonly used for the two group classification problem when the covariance matrices in the two populations are substantially unequal. This procedure is optimal when both populations are multivariate normal with known means and covariance matrices. This study examined the robustness of the QDF to non-normality. Sampling experiments were conducted to estimate expected actual error rates for the QDF when sampling from a variety of non-normal distributions. Results indicated that the QDF was robust to non-normality except when the distributions were highly skewed, in which case relatively large deviations from optimal were observed. In all cases studied the average probabilities of misclassification were relatively stable while the individual population error rates exhibited considerable variability.     

Minimax property of stein's estimator

Stein's estimator and some other estimators of the mean of a K-variate normal distribution are known to dominate the maximum likelihood estimator under quadratic loss for K > 3, and are therefore minimax. In this paper it is shown that the minimax property of Stein's rule is preserved with respect to a generalized loss function.     

Uniformly minimum variance unbiased estimation in lognormal and related distributions

The uniformly mimimum variance unbiased estimators and their variances from independent samples of lognormal distributions are concisely expressed using the hypergeometric functions