Low dose risk estimation via simultaneous statistical inferences

Summary.  The paper develops and studies simultaneous confidence bounds that are useful for making low dose inferences in quantitative risk analysis. Application is intended for risk assessment studies where human, animal or ecological data are used to set safe low dose levels of a toxic agent, but where study information is limited to high dose levels of the agent. Methods are derived for estimating simultaneous, one-sided, upper confidence limits on risk for end points measured on a continuous scale. From the simultaneous confidence bounds, lower confidence limits on the dose that is associated with a particular risk (often referred to as a bench-mark dose ) are calculated. An important feature of the simultaneous construction is that any inferences that are based on inverting the simultaneous confidence bounds apply automatically to inverse bounds on the bench-mark dose.     

翻译理论新标准与语言学理论

语言学的发展一直在不断地影响着翻译理论的发展,只不过有时这种影响很间接,尼达的译学思想在中国翻译界一向占据着重要的地位,但这位大师最近宣布其观点已经发生根本变化,尼达学术观点的变化无疑会给目前译学建设带来一定的负面影响。本文着重从翻译理论的作用、翻译标准及语言学与翻译的关系三个角度对尼达翻译思想的转变加以分析;重新阐述理论在译学框架中的地位及作用,理论和实践的关系及翻译理论的意义。     

几类循环图的分数染色数

通过构造几类图的最大独立集,给出了它们的分数染色数的下界;再通过构造具有该下界值的分数染色,给出了这几类循环图的分数染色数的上界,于是就确定了它们的分数染色数.     

加强研究生招生管理 提高招生质量

本文从招生名额的分配、招生宣传、专业课的命题评卷、复试四个招生的主要环节,论述了研究生招生过程中存在的一些问题及我校加强招生管理采取的措施.     

On pooling data summaries in the absence of interactions “response-by-study”

The standard hypothesis testing procedure in meta-analysis (or multi-center clinical trials) in the absence of treatment-by-center interaction relies on approximating the null distribution of the standard test statistic by a standard normal distribution. For relatively small sample sizes, the standard procedure has been shown by various authors to have poor control of the type I error probability, leading to too many liberal decisions. In this article, two test procedures are proposed, which rely on thet—distribution as the reference distribution. A simulation study indicates that the proposed procedures attain significance levels closer to the nominal level compared with the standard procedure.     

Sampling Strategies for Toxic Air Contaminants

Annual concentrations of toxic air contaminants are of primary concern from the perspective of chronic human exposure assessment and risk analysis. Despite recent advances in air quality monitoring technology, resource and technical constraints often impose limitations on the availability of a sufficient number of ambient concentration measurements for performing environmental risk analysis. Therefore, sample size limitations, representativeness of data, and uncertainties in the estimated annual mean concentration must be examined before performing quantitative risk analysis. In this paper, we discuss several factors that need to be considered in designing field-sampling programs for toxic air contaminants and in verifying compliance with environmental regulations. Specifically, we examine the behavior of SO2, TSP, and CO data as surrogates for toxic air contaminants and as examples of point source, area source, and line source-dominated pollutants, respectively, from the standpoint of sampling design. We demonstrate the use of bootstrap resampling method and normal theory in estimating the annual mean concentration and its 95% confidence bounds from limited sampling data, and illustrate the application of operating characteristic (OC) curves to determine optimum sample size and other sampling strategies. We also outline a statistical procedure, based on a one-sided t-test, that utilizes the sampled concentration data for evaluating whether a sampling site is compliance with relevant ambient guideline concentrations for toxic air contaminants.     

SHOULD WE ESTIMATE THE PROBABILITY OF CORRECT SELECTION?

Various authors, given k location parameters, have considered lower confidence bounds on (standardized) dserences between the largest and each of the other k - 1 parameters. They have then used these bounds to put lower confidence bounds on the probability of correct selection (PCS) in the same experiment (as was used for finding the lower bounds on differences). It is pointed out that this is an inappropriate inference procedure. Moreover, if the PCS refers to some later experiment it is shown that if a non-trivial confidence bound is possible then it is already possible to conclude, with greater confidence, that correct selection has occurred in the first experiment. The short answer to the question in the title is therefore ‘No’, but this should be qualified in the case of a Bayesian analysis.     

用模糊数学理论对汉诗英译本进行量化评估的初步构想

以模糊数学的理论为基础,初步探索用模糊综合评判定量评价汉诗英译本的基本方法,并对其中的关键步骤-判据集(或称评判因素)的设定和隶属度的确定进行了进一步的讨论.该方法虽然仍离不开人的主观参与,但它比纯粹的定性分析更为科学、系统.     

论为师育人之道

本文从理论与实践的结合上 ,阐述了教师教书育人的神圣职责 ,从“晓之以理、动之以情、教之以严、导之以行、授之以渔、示之以范”六个方面 ,探讨了师者育人之道。     

汽轮发电机组轴系磁阻尼器抑振方案优选计算分析

采用有限元与轴承及磁阻尼器动特性线性简化模型建立大型汽轮机转子系统不平衡振动响应计算模型;选择典型不平衡状态,采用多种磁阻尼器布置方案对BBC公司汽轮发电机组轴系振动的抑振效果进行分析对比优选,结果表明在中压转子段采用大阻尼参数磁阻尼器抑振效果最佳。