Bayesian prediction of waiting times in stochastic models

The authors show how saddlepoint techniques lead to highly accurate approximations for Bayesian predictive densities and cumulative distribution functions in stochastic model settings where the prior is tractable, but not necessarily the likelihood or the predictand distribution. They consider more specifically models involving predictions associated with waiting times for semi‐Markov processes whose distributions are indexed by an unknown parameter θ. Bayesian prediction for such processes when they are not stationary is also addressed and the inverse‐Gaussian based saddlepoint approximation of Wood, Booth & Butler (1993) is shown to accurately deal with the nonstationarity whereas the normal‐based Lugannani & Rice (1980) approximation cannot, Their methods are illustrated by predicting various waiting times associated with M/M/q and M/G/1 queues. They also discuss modifications to the matrix renewal theory needed for computing the moment generating functions that are used in the saddlepoint methods.     

Nonparametric curve estimation with missing data: A general empirical process approach

A general nonparametric imputation procedure, based on kernel regression, is proposed to estimate points as well as set- and function-indexed parameters when the data are missing at random (MAR). The proposed method works by imputing a specific function of a missing value (and not the missing value itself), where the form of this specific function is dictated by the parameter of interest. Both single and multiple imputations are considered. The associated empirical processes provide the right tool to study the uniform convergence properties of the resulting estimators. Our estimators include, as special cases, the imputation estimator of the mean, the estimator of the distribution function proposed by Cheng and Chu [1996. Kernel estimation of distribution functions and quantiles with missing data. Statist. Sinica 6, 63–78], imputation estimators of a marginal density, and imputation estimators of regression functions.     

Impact of Hazardous Substances Regulations on Small Firms in Delaware and New Jersey

Regulations under the 1990 Amendments to the Clean Air Act impose significant requirements on firms handling hazardous chemicals. The nature of the regulations would suggest that small firms, because of limited resources and other structural limitations, would experience more difficulty complying with the regulations than large firms. To understand the difficulties imposed by the regulations on small firms, we interviewed ten small firms in Delaware and New Jersey, states with existing hazardous regulations similar to those being considered by the U.S. Environmental Protection Agency, and evaluated their responses to state regulations. The impacts of the environmental regulations on the firms and on the risk levels of their businesses are discussed. Propositions for research into small firms compliance are developed. Possible means for reducing the regulatory burden on small firms while enhancing regulatory effectiveness are suggested.     

Expressing Estimators of Expected Quality Adjusted Survival as Functions of Nelson-Aalen Estimators

Quality adjusted survival has been increasingly advocated in clinical trials to be assessed as a synthesis of survival and quality of life. We investigate nonparametric estimation of its expectation for a general multistate process with incomplete follow-up data. Upon establishing a representation of expected quality adjusted survival through marginal distributions of a set of defined events, we propose two estimators for expected quality adjusted survival. Expressed as functions of Nelson-Aalen estimators, the two estimators are strongly consistent and asymptotically normal. We derive their asymptotic variances and propose sample-based variance estimates, along with evaluation of asymptotic relative efficiency. Monte Carlo studies show that these estimation procedures perform well for practical sample sizes. We illustrate the methods using data from a national, multicenter AIDS clinical trial.     

Weighted Approximations to Continuous Time Martingales with Applications

A weighted approximation to a sequence of continuous time martingales by a time transformed Wiener process is established. The basic tool of proof is the Skorohod imbedding for martingale difference sequences. As an application of the main result a useful weighted approximation to the randomly weighted uniform empirical process is derived. A number of other applications are also discussed.     

Random Bernstein Polynomials

Random Bernstein polynomials which are also probability distribution functions on the closed unit interval are studied. The probability law of a Bernstein polynomial so defined provides a novel prior on the space of distribution functions on [0, 1] which has full support and can easily select absolutely continuous distribution functions with a continuous and smooth derivative. In particular, the Bernstein polynomial which approximates a Dirichlet process is studied. This may be of interest in Bayesian non-parametric inference. In the second part of the paper, we study the posterior from a Bernstein–Dirichlet prior and suggest a hybrid Monte Carlo approximation of it. The proposed algorithm has some aspects of novelty since the problem under examination has a changing dimension parameter space.     

Kernel Density Estimation with Generalized Binning

We propose kernel density estimators based on prebinned data. We use generalized binning schemes based on the quantiles points of a certain auxiliary distribution function. Therein the uniform distribution corresponds to usual binning. The statistical accuracy of the resulting kernel estimators is studied, i.e. we derive mean squared error results for the closeness of these estimators to both the true function and the kernel estimator based on the original data set. Our results show the influence of the choice of the auxiliary density on the binned kernel estimators and they reveal that non-uniform binning can be worthwhile.     

A Nonparametric Test for the Parallelism of Two First-Order Autoregressive Processes

A nonparametric testing procedure for the parallelism of two first-order autoregressive processes is presented. This paper discuss the Mann–Whitney statistic, its natural competitor two-sample t -test, and the bootstrap method. It studies the asymptotic efficacies of the studentized Mann–Whitney statistic and the t -test statistic with their relative efficiency. Simulation results for comparing the powers of these test statistics are also presented.     

Extensions of Fill's algorithm for perfect simulation

Fill's algorithm for perfect simulation for attractive finite state space models, unbiased for user impatience, is presented in terms of stochastic recursive sequences and extended in two ways. Repulsive discrete Markov random fields with two coding sets like the auto-Poisson distribution on a lattice with 4-neighbourhood can be treated as monotone systems if a particular partial ordering and quasi-maximal and quasi-minimal states are used. Fill's algorithm then applies directly. Combining Fill's rejection sampling with sandwiching leads to a version of the algorithm which works for general discrete conditionally specified repulsive models. Extensions to other types of models are briefly discussed.