Alternative estimators in logistic regression when the data are collinear

Logistic regression using conditional maximum likelihood estimation has recently gained widespread use. Many of the applications of logistic regression have been in situations in which the independent variables are collinear. It is shown that collinearity among the independent variables seriously effects the conditional maximum likelihood estimator in that the variance of this estimator is inflated in much the same way that collinearity inflates the variance of the least squares estimator in multiple regression. Drawing on the similarities between multiple and logistic regression several alternative estimators, which reduce the effect of the collinearity and are easy to obtain in practice, are suggested and compared in a simulation study.     

Testing for a change point in a sequence of exponential random variables with repeated values

Two test statistics are proposed for the change-point problem with repeated values when the data follow an exponential distribution. The properties of these two statistics have been studied and their asymptotic distributions under the alternative have been derived. The powers of the two test statistics are compared. Real-data examples are presented to illustrate the application of these tests.     

Uniform Test for Predictive Regression With AR Errors

Testing predictability is of importance in economics and finance. Based on a predictive regression model with independent and identically distributed errors, some uniform tests have been proposed in the literature without distinguishing whether the predicting variable is stationary or nearly integrated. In this article, we extend the empirical likelihood methods of Zhu, Cai, and Peng with independent errors to the case of an AR error process. Again, the proposed new tests do not need to know whether the predicting variable is stationary or nearly integrated, and whether it has a finite variance or an infinite variance. A simulation study shows the new methodologies perform well in finite sample.     

Evidential inference for diffusion-type processes

This article analyses diffusion-type processes from a new point-of-view. Consider two statistical hypotheses on a diffusion process. We do not use a classical test to reject or accept one hypothesis using the Neyman–Pearson procedure and do not involve Bayesian approach. As an alternative, we propose using a likelihood paradigm to characterizing the statistical evidence in support of these hypotheses. The method is based on evidential inference introduced and described by Royall [Royall R. Statistical evidence: a likelihood paradigm. London: Chapman and Hall; 1997]. In this paper, we extend the theory of Royall to the case when data are observations from a diffusion-type process instead of iid observations. The empirical distribution of likelihood ratio is used to formulate the probability of strong, misleading and weak evidences. Since the strength of evidence can be affected by the sampling characteristics, we present a simulation study that demonstrates these effects. Also we try to control misleading evidence and reduce them by adjusting these characteristics. As an illustration, we apply the method to the Microsoft stock prices.     

Time series models with asymmetric Laplace innovations

We propose autoregressive moving average (ARMA) and generalized autoregressive conditional heteroscedastic (GARCH) models driven by asymmetric Laplace (AL) noise. The AL distribution plays, in the geometric-stable class, the analogous role played by the normal in the alpha-stable class, and has shown promise in the modelling of certain types of financial and engineering data. In the case of an ARMA model we derive the marginal distribution of the process, as well as its bivariate distribution when separated by a finite number of lags. The calculation of exact confidence bands for minimum mean-squared error linear predictors is shown to be straightforward. Conditional maximum likelihood-based inference is advocated, and corresponding asymptotic results are discussed. The models are particularly suited for processes that are skewed, peaked, and leptokurtic, but which appear to have some higher order moments. A case study of a fund of real estate returns reveals that AL noise models tend to deliver a superior fit with substantially less parameters than normal noise counterparts, and provide both a competitive fit and a greater degree of numerical stability with respect to other skewed distributions.     

A note on bias reduction of maximum likelihood estimates for the scalar skew t distribution

The skew t distribution is a flexible parametric family to fit data, because it includes parameters that let us regulate skewness and kurtosis. A problem with this distribution is that, for moderate sample sizes, the maximum likelihood estimator of the shape parameter is infinite with positive probability. In order to try to solve this problem, Sartori (2006) has proposed using a modified score function as an estimating equation for the shape parameter. In this note we prove that the resulting modified maximum likelihood estimator is always finite, considering the degrees of freedom as known and greater than or equal to 2.     

BL-GARCH models with elliptical distributed innovations

In this work, we discuss the class of bilinear GARCH (BL-GARCH) models that are capable of capturing simultaneously two key properties of non-linear time series: volatility clustering and leverage effects. It has often been observed that the marginal distributions of such time series have heavy tails; thus we examine the BL-GARCH model in a general setting under some non-normal distributions. We investigate some probabilistic properties of this model and we conduct a Monte Carlo experiment to evaluate the small-sample performance of the maximum likelihood estimation (MLE) methodology for various models. Finally, within-sample estimation properties were studied using S&P 500 daily returns, when the features of interest manifest as volatility clustering and leverage effects. The main results suggest that the Student-t BL-GARCH seems highly appropriate to describe the S&P 500 daily returns.     

Odd-Burr generalized family of distributions with some applications

We study a new family of continuous distributions with two extra shape parameters called the Burr generalized family of distributions. We investigate the shapes of the density and hazard rate function. We derive explicit expressions for some of its mathematical quantities. The estimation of the model parameters is performed by maximum likelihood. We prove the flexibility of the new family by means of applications to two real data sets. Furthermore, we propose a new extended regression model based on the logarithm of the Burr generalized distribution. This model can be very useful to the analysis of real data and provide more realistic fits than other special regression models.     

Is prenatal sex selection associated with lower female child mortality?

I examine whether prenatal sex selection has substituted postnatal excess female mortality by analysing the dynamics of child sex ratios between 1980 and 2015 using country-level life table data. I decompose changes in child sex ratios into a ‘fertility’ component attributable to prenatal sex selection and a ‘mortality’ component attributable to sex differentials in postnatal survival. Although reductions in numbers of excess female deaths have accompanied increases in missing female births in all countries experiencing the emergence of prenatal sex selection, relative excess female mortality has persisted in some countries but not others. In South Korea, Armenia, and Azerbaijan, mortality reductions favouring girls accompanied increases in prenatal sex selection. In India, excess female mortality was much higher and largely stable as prenatal sex selection emerged, but slight reductions were seen in the 2000s. In China, although absolute measures showed reductions, relative excess female mortality persisted as prenatal sex selection increased.     

Early stopping in seamless phase I/II clinical trials

In recent years, seamless phase I/II clinical trials have drawn much attention, as they consider both toxicity and efficacy endpoints in finding an optimal dose (OD). Engaging an appropriate number of patients in a trial is a challenging task. This paper attempts a dynamic stopping rule to save resources in phase I/II trials. That is, the stopping rule aims to save patients from unnecessary toxic or subtherapeutic doses. We allow a trial to stop early when widths of the confidence intervals for the dose-response parameters become narrower or when the sample size is equal to a predefined size, whichever comes first. The simulation study of dose-response scenarios in various settings demonstrates that the proposed stopping rule can engage an appropriate number of patients. Therefore, we suggest its use in clinical trials.