Effectiveness of combinations of Gaussian graphical models for model building

Combining statistical models is an useful approach in all the research area where a global picture of the problem needs to be constructed by binding together evidence from different sources [M.S. Massa and S.L. Lauritzen Combining Statistical Models, M. Viana and H. Wynn, eds., American Mathematical Society, Providence, RI, 2010, pp. 239–259]. In this paper, we investigate the effectiveness of combining a fixed number of Gaussian graphical models respecting some consistency assumptions in problems of model building. In particular, we use the meta-Markov combination of Gaussian graphical models as detailed in Massa and Lauritzen and compare model selection results obtained by combining selections over smaller sets of variables with selection results over all variables of interest. In order to do so, we carry out some simulation studies in which different criteria are considered for the selection procedures. We conclude that the combination performs, generally, better than global estimation, is computationally simpler by virtue of having fewer and simpler models to work on, and has an intuitive appeal to a wide variety of contexts.     

Hierarchical modeling with gaussian processes

We formulate a hierarchical version of the Gaussian Process model. In particular, we assume there to be data on several units randomly drawn from the same population. For each unit, several responses are available that arise from a Gaussian Process model. The parameters characterizing the Gaussian Process model for the units are modeled to arise from normal or gamma distributions. Results for two simulations are given that compare the performance of the hierarchical and non-hierarchical models.     

Inverse Gaussian Distribution for Modeling Conditional Durations in Finance

The durations between market activities such as trades and quotes provide useful information on the underlying assets while analyzing financial time series. In this article, we propose a stochastic conditional duration model based on the inverse Gaussian distribution. The non-monotonic nature of the failure rate of the inverse Gaussian distribution makes it suitable for modeling the durations in financial time series. The parameters of the proposed model are estimated by an efficient importance sampling method. A simulation experiment is conducted to check the performance of the estimators. These estimates are used to compute estimated hazard functions and to compare with the empirical hazard functions. Finally, a real data analysis is provided to illustrate the practical utility of the models.     

Bayesian texture segmentation of weed and crop images using reversible jump Markov chain Monte Carlo methods

Summary. A Bayesian method for segmenting weed and crop textures is described and implemented. The work forms part of a project to identify weeds and crops in images so that selective crop spraying can be carried out. An image is subdivided into blocks and each block is modelled as a single texture. The number of different textures in the image is assumed unknown. A hierarchical Bayesian procedure is used where the texture labels have a Potts model (colour Ising Markov random field) prior and the pixels within a block are distributed according to a Gaussian Markov random field, with the parameters dependent on the type of texture. We simulate from the posterior distribution by using a reversible jump Metropolis–Hastings algorithm, where the number of different texture components is allowed to vary. The methodology is applied to a simulated image and then we carry out texture segmentation on the weed and crop images that motivated the work.     

A new reproducing kernel-based nonlinear dimension reduction method for survival data

Based on the theories of sliced inverse regression (SIR) and reproducing kernel Hilbert space (RKHS), a new approach RDSIR (RKHS-based Double SIR) to nonlinear dimension reduction for survival data is proposed. An isometric isomorphism is constructed based on the RKHS property, then the nonlinear function in the RKHS can be represented by the inner product of two elements that reside in the isomorphic feature space. Due to the censorship of survival data, double slicing is used to estimate the weight function to adjust for the censoring bias. The nonlinear sufficient dimension reduction (SDR) subspace is estimated by a generalized eigen-decomposition problem. The asymptotic property of the estimator is established based on the perturbation theory. Finally, the performance of RDSIR is illustrated on simulated and real data. The numerical results show that RDSIR is comparable with the linear SDR method. Most importantly, RDSIR can also effectively extract nonlinearity from survival data.     

Estimation of conditional cumulative incidence functions under generalized semiparametric regression models with missing covariates,with application to analysis of biomarker correlates in vaccine trials

This article presents generalized semiparametric regression models for conditional cumulative incidence functions with competing risks data when covariates are missing by sampling design or happenstance. A doubly robust augmented inverse probability weighted (AIPW) complete-case approach to estimation and inference is investigated. This approach modifies IPW complete-case estimating equations by exploiting the key features in the relationship between the missing covariates and the phase-one data to improve efficiency. An iterative numerical procedure is derived to solve the nonlinear estimating equations. The asymptotic properties of the proposed estimators are established. A simulation study examining the finite-sample performances of the proposed estimators shows that the AIPW estimators are more efficient than the IPW estimators. The developed method is applied to the RV144 HIV-1 vaccine efficacy trial to investigate vaccine-induced IgG binding antibodies to HIV-1 as correlates of acquisition of HIV-1 infection while taking account of whether the HIV-1 sequences are near or far from the HIV-1 sequences represented in the vaccine construct.     

Preference for Flexibility in a Savage Framework

We study preferences over Savage acts that map states to opportunity sets and satisfy the Savage axioms. Preferences over opportunity sets may exhibit a preference for flexibility due to an implicit uncertainty about future preferences reflecting anticipated unforeseen contingencies. The main result of this paper characterizes maximization of the expected indirect utility in terms of an ‘Indirect Stochastic Dominance’ axiom that expresses a preference for ‘more opportunities in expectation.’ The key technical tool of the paper, a version of Möbius inversion, has been imported from the theory of nonadditive belief functions; it allows an alternative representation using Choquet integration, and yields a simple proof of Kreps' (1979) classic result.