Influence analysis in multivariate linear general models

In this paper we obtain several influence measures for the multivariate linear general model through the approach proposed by Muñoz-Pichardo et al. (1995), which is based on the concept of conditional bias. An interesting charasteristic of this approach is that it does not require any distributional hypothesis. Appling the obtained results to the multivariate regression model, we obtain some measures proposed by other authors. Nevertheless, on the results obtained in this paper, we emphasize two aspects. First, they provide a theoretical foundation for measures proposed by other authors for the mul¬tivariate regression model. Second, they can be applied to any linear model that can be formulated as a particular case of the multivariate linear general model. In particular, we carry out an application to the multivariate analysis of covariance.     

A class of semiparametric transormation frailty models with application to estimating treatment effects and heterogenity in aids clinical traials

Muitivariate failure time data are common in medical research; com¬monly used statistical models for such correlated failure-time data include frailty and marginal models. Both types of models most often assume pro¬portional hazards (Cox, 1972); but the Cox model may not fit the data well This article presents a class of linear transformation frailty models that in¬cludes, as a special case, the proportional hazards model with frailty. We then propose approximate procedures to derive the best linear unbiased es¬timates and predictors of the regression parameters and frailties. We apply the proposed methods to analyze results of a clinical trial of different dose levels of didansine (ddl) among HIV-infected patients who were intolerant of zidovudine (ZDV). These methods yield estimates of treatment effects and of frailties corresponding to patient groups defined by clinical history prior to entry into the trial.     

Generalized additive mixed models

Following the extension from linear mixed models to additive mixed models, extension from generalized linear mixed models to generalized additive mixed models is made, Algorithms are developed to compute the MLE's of the nonlinear effects and the covariance structures based on the penalized marginal likelihood. Convergence of the algorithms and selection of the smooth param¬eters are discussed.     

Estimation of parameters of a pareto distribution by generalized order statistics

In this paper we address the problem of estimating the parameters of Pareto II distribution based on generalized order statistics. The estimators based on order statistics and record values are shown to be special cases of these estimators.     

Modified ridge analyses under nonstandard

A well-known procedure for the optimization of a second-degree response function over a spherical region of interest is that of ridge analysis. Khuri and Myers (1979) introduced a modification of this procedure by incorporating a certain constraint on the prediction variance. Both procedures, however, assume that the response variable has a constant variance throughtout the experimental region. In the present article, we consider two extensions to Khuri and Myers modifioed ridge analysis. The first extension relaxes the constant variance assumption. In the second extension. generalised linear models are used instead of the trasitional linear model. which are commenly used in responce variables that are not necessaily continusly distribution, including these have discreate distributions, Two examples are presented to illustrate the implementation of the proposed extensions.     

Multiple deletion measures and conditional influence in regression model

The joint effect of the deletion of the ith and jih cases is given by Gray and Ling (1984), they discussed the influence measures for influential subsets in linear regression analysis. The present paper is concerned with multiple sets of deletion measures in the linear regression model. In particular we are interested in the effects of the jointly and conditional influence analysis for the detection of two influential subsets.     

Ridge Estimation to the Restricted Linear Model

This article is concerned with the problem of multicollinearity in a linear model with linear restrictions. After introducing a spheral restricted condition, a new restricted ridge estimation method is proposed by minimizing the sum of squared residuals. The property of the new estimator in its superiority over the ordinary restricted least squares estimation is then theoretically analyzed. Furthermore, a sufficient and necessary condition for selecting the ridge parameter k is obtained. To simplify the selection of the ridge parameter, a sufficient condition is also given. Finally, a numerical example demonstrates the merit of the new method in the aspect of solving the multicollinearity over the ordinary restricted least squares estimation.     

Nonparametric Trend Estimation for Periodic Autoregressive Time Series

A periodically stationary time series has seasonal variances. A local linear trend estimation is proposed to accommodate unequal variances. A comparison of this proposed estimator with the estimator commonly used for a stationary time series is provided. The optimal bandwidth selection for this new trend estimator is discussed.     

Measurement error in regression analysis

Consider the linear regression model Y = Xθ+ ε where Y denotes a vector of n observations on the dependent variable, X is a known matrix, θ is a vector of parameters to be estimated and e is a random vector of uncorrelated errors. If X'X is nearly singular, that is if the smallest characteristic root of X'X s small then a small perurbation in the elements of X, such as due to measurement errors, induces considerable variation in the least squares estimate of θ. In this paper we examine for the asymptotic case when n is large the effect of perturbation with regard to the bias and mean squared error of the estimate.