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11.
In this paper we study estimating the joint conditional distributions of multivariate longitudinal outcomes using regression models and copulas. For the estimation of marginal models, we consider a class of time-varying transformation models and combine the two marginal models using nonparametric empirical copulas. Our models and estimation method can be applied in many situations where the conditional mean-based models are not good enough. Empirical copulas combined with time-varying transformation models may allow quite flexible modelling for the joint conditional distributions for multivariate longitudinal data. We derive the asymptotic properties for the copula-based estimators of the joint conditional distribution functions. For illustration we apply our estimation method to an epidemiological study of childhood growth and blood pressure.  相似文献   
12.
Generalised estimating equations (GEE) for regression problems with vector‐valued responses are examined. When the response vectors are of mixed type (e.g. continuous–binary response pairs), the GEE approach is a semiparametric alternative to full‐likelihood copula methods, and is closely related to Prentice & Zhao's mean‐covariance estimation equations approach. When the response vectors are of the same type (e.g. measurements on left and right eyes), the GEE approach can be viewed as a ‘plug‐in’ to existing methods, such as the vglm function from the state‐of‐the‐art VGAM package in R. In either scenario, the GEE approach offers asymptotically correct inferences on model parameters regardless of whether the working variance–covariance model is correctly or incorrectly specified. The finite‐sample performance of the method is assessed using simulation studies based on a burn injury dataset and a sorbinil eye trial dataset. The method is applied to data analysis examples using the same two datasets, as well as to a trivariate binary dataset on three plant species in the Hunua ranges of Auckland.  相似文献   
13.
Spatio‐temporal modelling is an increasingly popular topic in Statistics. Our paper contributes to this line of research by developing the theory, simulation and inference for a spatio‐temporal Ornstein–Uhlenbeck process. We conduct detailed simulation studies and demonstrate the practical relevance of these processes in an empirical study of radiation anomaly data. Finally, we describe how predictions can be carried out in the Gaussian setting.  相似文献   
14.
Since the Last Planner System® (LPS) was devised in the early 90s, a number of studies have pointed out the need to understand the underlying theory in which it is based on. The Language-Action Perspective (LAP) has been suggested as a suitable approach to understand the management of commitments in the LPS. This paper aims to assess the contribution of LAP to understand construction planning and control systems based on LPS. Two case studies were carried out in different construction companies, both highly experienced on the use of LPS. The results reveal the role of LAP for creating explicit representations of commitment flows that can be used to explain the sources of complexity and failures in planning systems, as well as for describing the profile of planning and control meetings.  相似文献   
15.
Predicting the arrival time of a transit vehicle involves not only knowledge of its current position and schedule adherence, but also traffic conditions along the remainder of the route. Road networks are dynamic and can quickly change from free‐flowing to highly congested, which impacts the arrival time of transit vehicles, particularly buses which often share the road with other vehicles, so reliable predictions need to account for real‐time and future traffic conditions. The first step in this process is to construct a framework with which road state (traffic conditions) can be estimated using real‐time transit vehicle position data. Our proposed framework implements a vehicle model using a particle filter to estimate road travel times, which are used in a second model to estimate real‐time traffic conditions. Although development and testing took place in Auckland, New Zealand, we generalised each component to make the framework compatible with other public transport systems around the world. We demonstrate the real‐time feasibility and performance of our approach in real‐time, where a combination of R and C++ was used to obtain the necessary performance results. Future work will use these estimated traffic conditions in combination with historical data to obtain reliable arrival time predictions of transit vehicles.  相似文献   
16.
17.
Longitudinal studies are the gold standard of empirical work and stress research whenever experiments are not plausible. Frequently, scales are used to assess risk factors and their consequences, and cross-lagged effects are estimated to determine possible risks. Methods to translate cross-lagged effects into risk ratios to facilitate risk assessment do not yet exist, which creates a divide between psychological and epidemiological work stress research. The aim of the present paper is to demonstrate how cross-lagged effects can be used to assess the risk ratio of different levels of psychosocial safety climate (PSC) in organisations, an important psychosocial risk for the development of depression. We used available longitudinal evidence from the Australian Workplace Barometer (N?=?1905) to estimate cross-lagged effects of PSC on depression. We applied continuous time modelling to obtain time-scalable cross effects. These were further investigated in a 4-year Monte Carlo simulation, which translated them into 4-year incident rates. Incident rates were determined by relying on clinically relevant 2-year periods of depression. We suggest a critical value of PSC?=?26 (corresponding to ?1.4 SD), which is indicative of more than 100% increased incidents of persistent depressive disorder in 4-year periods compared to average levels of PSC across 4 years.  相似文献   
18.
This paper presents an aided design methodology of flexible manufacturing system control with a view to industrial implementation. The approach considered through a modelling phase, the a validation phase by simulation and finally a distributed implementation phase. In the modelling phase, based on the Petri net formalism, we demonstrate the hierarchical aspect which separates the part flow control and the product resource control. In addition, we emphasize generic aspects which allow us to use an object-oriented approach. These aspects and the set of modelled objects are directly used in the simulation and production phases after an automatic translation in an implementation language (ADA in our case). In consequence, the distributed location for those two phases is well facilitated from the viewpoint of the approach used.  相似文献   
19.
The inherent instabilityof complex supplychains is well understood and documented; the potential benefits of taking time out of the chain in terms of reduced inventory and lower operating costs are clearly substantial. There is now a broad community of managers and practitioners who know ‘what’ in principle needs to be done. The issue for all is ‘how’ to go about it for their particular business. This paper builds on an organizational trade-off model through which logistics moderates the conflicting demands and culture of manufacturing on the one hand and marketing on the other. The paper introduces three practical techniques for securing the benefits of supply chain management: time-based simulation; cost-to-serve; and piloting change. Used together these methodologies can deliver breakthrough in supply chain effectiveness.  相似文献   
20.
Traceability is normally difficult to achieve in continuous processes, since there are no natural batch structures. In this article, we demonstrate flow-based simulation using process data to improve traceability in a continuous pelletising process. Using the simulation model, the engineers could test the impacts of process disturbances, identify cause and effect relations and aid control in case of process disturbances. In a field trial where the chemistry of an additive was varied during production of a special product, the simulation forecasts predicted the level of the chemical content after the plant within the errors that the engineers found acceptable.  相似文献   
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