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941.
Plotting of log−log survival functions against time for different categories or combinations of categories of covariates is perhaps the easiest and most commonly used graphical tool for checking proportional hazards (PH) assumption. One problem in the utilization of the technique is that the covariates need to be categorical or made categorical through appropriate grouping of the continuous covariates. Subjectivity in the decision making on the basis of eye-judgment of the plots and frequent inconclusiveness arising in situations where the number of categories and/or covariates gets larger are among other limitations of this technique. This paper proposes a non-graphical (numerical) test of the PH assumption that makes use of log−log survival function. The test enables checking proportionality for categorical as well as continuous covariates and overcomes the other limitations of the graphical method. Observed power and size of the test are compared to some other tests of its kind through simulation experiments. Simulations demonstrate that the proposed test is more powerful than some of the most sensitive tests in the literature in a wide range of survival situations. An example of the test is given using the widely used gastric cancer data. 相似文献
942.
The estimation of data transformation is very useful to yield response variables satisfying closely a normal linear model. Generalized linear models enable the fitting of models to a wide range of data types. These models are based on exponential dispersion models. We propose a new class of transformed generalized linear models to extend the Box and Cox models and the generalized linear models. We use the generalized linear model framework to fit these models and discuss maximum likelihood estimation and inference. We give a simple formula to estimate the parameter that index the transformation of the response variable for a subclass of models. We also give a simple formula to estimate the rth moment of the original dependent variable. We explore the possibility of using these models to time series data to extend the generalized autoregressive moving average models discussed by Benjamin et al. [Generalized autoregressive moving average models. J. Amer. Statist. Assoc. 98, 214–223]. The usefulness of these models is illustrated in a simulation study and in applications to three real data sets. 相似文献
943.
Robust tests for the common principal components model 总被引:1,自引:0,他引:1
Graciela Boente Ana M. Pires Isabel M. Rodrigues 《Journal of statistical planning and inference》2009
When dealing with several populations, the common principal components (CPC) model assumes equal principal axes but different variances along them. In this paper, a robust log-likelihood ratio statistic allowing to test the null hypothesis of a CPC model versus no restrictions on the scatter matrices is introduced. The proposal plugs into the classical log-likelihood ratio statistic robust scatter estimators. Using the same idea, a robust log-likelihood ratio and a robust Wald-type statistic for testing proportionality against a CPC model are considered. Their asymptotic distributions under the null hypothesis and their partial influence functions are derived. A small simulation study allows to compare the behavior of the classical and robust tests, under normal and contaminated data. 相似文献
944.
This paper is mainly concerned with minimax estimation in the general linear regression model y=Xβ+ε under ellipsoidal restrictions on the parameter space and quadratic loss function. We confine ourselves to estimators that are linear in the response vector y . The minimax estimators of the regression coefficient β are derived under homogeneous condition and heterogeneous condition, respectively. Furthermore, these obtained estimators are the ridge-type estimators and mean dispersion error (MDE) superior to the best linear unbiased estimator b=(X′W-1X)-1X′W-1y under some conditions. 相似文献
945.
Rosa Arboretti Giancristofaro Stefano Bonnini Fortunato Pesarin 《Statistics and Computing》2009,19(2):209-216
In many sciences researchers often meet the problem of establishing if the distribution of a categorical variable is more
concentrated, or less heterogeneous, in population P
1 than in population P
2. An approximate nonparametric solution to this problem is discussed within the permutation context. Such a solution has similarities
to that of testing for stochastic dominance, that is, of testing under order restrictions, for ordered categorical variables.
Main properties of given solution and a Monte Carlo simulation in order to evaluate its degree of approximation and its power
behaviour are examined. Two application examples are also discussed. 相似文献
946.
The data collection process and the inherent population structure are the main causes for clustered data. The observations in a given cluster are correlated, and the magnitude of such correlation is often measured by the intra-cluster correlation coefficient. The intra-cluster correlation can lead to an inflated size of the standard F test in a linear model. In this paper, we propose a solution to this problem. Unlike previous adjustments, our method does not require estimation of the intra-class correlation, which is problematic especially when the number of clusters is small. Our simulation results show that the new method outperforms the existing methods. 相似文献
947.
Lili Tian Albert Vexler Li Yan Enrique F. Schisterman 《Journal of statistical planning and inference》2009
In many diagnostic studies, multiple diagnostic tests are performed on each subject or multiple disease markers are available. Commonly, the information should be combined to improve the diagnostic accuracy. We consider the problem of comparing the discriminatory abilities between two groups of biomarkers. Specifically, this article focuses on confidence interval estimation of the difference between paired AUCs based on optimally combined markers under the assumption of multivariate normality. Simulation studies demonstrate that the proposed generalized variable approach provides confidence intervals with satisfying coverage probabilities at finite sample sizes. The proposed method can also easily provide P-values for hypothesis testing. Application to analysis of a subset of data from a study on coronary heart disease illustrates the utility of the method in practice. 相似文献
948.
Modified inference about the mean of the exponential distribution using moving extreme ranked set sampling 总被引:1,自引:1,他引:0
The maximum likelihood estimator (MLE) and the likelihood ratio test (LRT) will be considered for making inference about the
scale parameter of the exponential distribution in case of moving extreme ranked set sampling (MERSS). The MLE and LRT can
not be written in closed form. Therefore, a modification of the MLE using the technique suggested by Maharota and Nanda (Biometrika
61:601–606, 1974) will be considered and this modified estimator will be used to modify the LRT to get a test in closed form
for testing a simple hypothesis against one sided alternatives. The same idea will be used to modify the most powerful test
(MPT) for testing a simple hypothesis versus a simple hypothesis to get a test in closed form for testing a simple hypothesis
against one sided alternatives. Then it appears that the modified estimator is a good competitor of the MLE and the modified
tests are good competitors of the LRT using MERSS and simple random sampling (SRS). 相似文献
949.
In this paper, we study the MDPDE (minimizing a density power divergence estimator), proposed by Basu et al. (Biometrika 85:549–559,
1998), for mixing distributions whose component densities are members of some known parametric family. As with the ordinary
MDPDE, we also consider a penalized version of the estimator, and show that they are consistent in the sense of weak convergence.
A simulation result is provided to illustrate the robustness. Finally, we apply the penalized method to analyzing the red
blood cell SLC data presented in Roeder (J Am Stat Assoc 89:487–495, 1994).
This research was supported (in part) by KOSEF through Statistical Research Center for Complex Systems at Seoul National University. 相似文献
950.
In this note we consider the equality of the ordinary least squares estimator (OLSE) and the best linear unbiased estimator
(BLUE) of the estimable parametric function in the general Gauss–Markov model. Especially we consider the structures of the
covariance matrix V for which the OLSE equals the BLUE. Our results are based on the properties of a particular reparametrized version of the
original Gauss–Markov model.
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