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21.
    
The author is concerned with log‐linear estimators of the size N of a population in a capture‐recapture experiment featuring heterogeneity in the individual capture probabilities and a time effect. He also considers models where the first capture influences the probability of subsequent captures. He derives several results from a new inequality associated with a dispersive ordering for discrete random variables. He shows that in a log‐linear model with inter‐individual heterogeneity, the estimator N is an increasing function of the heterogeneity parameter. He also shows that the inclusion of a time effect in the capture probabilities decreases N in models without heterogeneity. He further argues that a model featuring heterogeneity can accommodate a time effect through a small change in the heterogeneity parameter. He demonstrates these results using an inequality for the estimators of the heterogeneity parameters and illustrates them in a Monte Carlo experiment  相似文献   
22.
    
Existing methods for meta‐analysis of diagnostic test accuracy focus primarily on a single index test. We propose models for the joint meta‐analysis of studies comparing multiple index tests on the same participants in paired designs. These models respect the grouping of data by studies, account for the within‐study correlation between the tests' true‐positive rates (TPRs) and between their false‐positive rates (FPRs) (induced because tests are applied to the same participants), and allow for between‐study correlations between TPRs and FPRs (such as those induced by threshold effects). We estimate models in the Bayesian setting. We demonstrate using a meta‐analysis of screening for Down syndrome with two tests: shortened humerus (arm bone), and shortened femur (thigh bone). Separate and joint meta‐analyses yielded similar TPR and FPR estimates. For example, the summary TPR for a shortened humerus was 35.3% (95% credible interval (CrI): 26.9, 41.8%) versus 37.9% (27.7, 50.3%) with joint versus separate meta‐analysis. Joint meta‐analysis is more efficient when calculating comparative accuracy: the difference in the summary TPRs was 0.0% (−8.9, 9.5%; TPR higher for shortened humerus) with joint versus 2.6% (−14.7, 19.8%) with separate meta‐analyses. Simulation and empirical analyses are needed to refine the role of the proposed methodology. Copyright © 2014 John Wiley & Sons, Ltd.  相似文献   
23.
    
Eliciting expert knowledge about several uncertain quantities is a complex task when those quantities exhibit associations. A well-known example of such a problem is eliciting knowledge about a set of uncertain proportions which must sum to 1. The usual approach is to assume that the expert's knowledge can be adequately represented by a Dirichlet distribution, since this is by far the simplest multivariate distribution that is appropriate for such a set of proportions. It is also the most convenient, particularly when the expert's prior knowledge is to be combined with a multinomial sample since then the Dirichlet is the conjugate prior family. Several methods have been described in the literature for eliciting beliefs in the form of a Dirichlet distribution, which typically involve eliciting from the expert enough judgements to identify uniquely the Dirichlet hyperparameters. We describe here a new method which employs the device of over-fitting, i.e. eliciting more than the minimal number of judgements, in order to (a) produce a more carefully considered Dirichlet distribution and (b) ensure that the Dirichlet distribution is indeed a reasonable fit to the expert's knowledge. The method has been implemented in a software extension of the Sheffield elicitation framework (SHELF) to facilitate the multivariate elicitation process.  相似文献   
24.
    
This paper considers five test statistics for comparing the recovery of a rapid growth‐based enumeration test with respect to the compendial microbiological method using a specific nonserial dilution experiment. The finite sample distributions of these test statistics are unknown, because they are functions of correlated count data. A simulation study is conducted to investigate the type I and type II error rates. For a balanced experimental design, the likelihood ratio test and the main effects analysis of variance (ANOVA) test for microbiological methods demonstrated nominal values for the type I error rate and provided the highest power compared with a test on weighted averages and two other ANOVA tests. The likelihood ratio test is preferred because it can also be used for unbalanced designs. It is demonstrated that an increase in power can only be achieved by an increase in the spiked number of organisms used in the experiment. The power is surprisingly not affected by the number of dilutions or the number of test samples. A real case study is provided to illustrate the theory. Copyright © 2013 John Wiley & Sons, Ltd.  相似文献   
25.
    
Stakeholders making decisions in public health and world trade need improved estimations of the burden‐of‐illness of foodborne infectious diseases. In this article, we propose a Bayesian meta‐analysis or more precisely a Bayesian evidence synthesis to assess the burden‐of‐illness of campylobacteriosis in France. Using this case study, we investigate campylobacteriosis prevalence, as well as the probabilities of different events that guide the disease pathway, by (i) employing a Bayesian approach on French and foreign human studies (from active surveillance systems, laboratory surveys, physician surveys, epidemiological surveys, and so on) through the chain of events that occur during an episode of illness and (ii) including expert knowledge about this chain of events. We split the target population using an exhaustive and exclusive partition based on health status and the level of disease investigation. We assume an approximate multinomial model over this population partition. Thereby, each observed data set related to the partition brings information on the parameters of the multinomial model, improving burden‐of‐illness parameter estimates that can be deduced from the parameters of the basic multinomial model. This multinomial model serves as a core model to perform a Bayesian evidence synthesis. Expert knowledge is introduced by way of pseudo‐data. The result is a global estimation of the burden‐of‐illness parameters with their accompanying uncertainty.  相似文献   
26.
《Statistics》2012,46(6):1396-1436
ABSTRACT

The paper deals with an asymptotic relative efficiency concept for confidence regions of multidimensional parameters that is based on the expected volumes of the confidence regions. Under standard conditions the asymptotic relative efficiencies of confidence regions are seen to be certain powers of the ratio of the limits of the expected volumes. These limits are explicitly derived for confidence regions associated with certain plugin estimators, likelihood ratio tests and Wald tests. Under regularity conditions, the asymptotic relative efficiency of each of these procedures with respect to each one of its competitors is equal to 1. The results are applied to multivariate normal distributions and multinomial distributions in a fairly general setting.  相似文献   
27.
Of the 324 petroleum refineries operating in the U.S. in 1982, only 149 were still in the hands of their original owners in 2007. Using duration analysis, this paper explores why refineries change ownership or shut down. Plants are more likely to ‘survive’ with their original owners if they are older or larger, but less likely if the owner is a major integrated firm, or the refinery is a more technologically complex one. This latter result differs from existing research on the issue. This paper also presents a split population model to relax the general assumption of the duration model that all refiners will eventually close down; the empirical results show that the split population model converges on a standard hazard model; the log-logistic version fits best. Finally, a multinomial logit model is estimated to analyze the factors that influence the refinery plant's choices of staying open, closing, or changing ownership. Plant size, age and technology usage have positive impacts on the likelihood that a refinery will stay open, or change ownership (rather than close down).  相似文献   
28.
Tests based on the Anderson–Darling statistic, a third moment statistic and the classical Pearson–Fisher X 2 statistic, along with its third-order component, are considered. A small critical value and power study are given. Some examples illustrate important applications.  相似文献   
29.
Zusammenfassung: In diesem Artikel wird der Weg von einem univariaten gemischten Poisson–Prozess, der in vielen Bereichen zum Z?hlen von Ereignissen benutzt wird, zu einem bivariaten gemischten Poisson–Prozess aufgezeigt. Dazu werden einige Eigenschaften des bivariaten Prozesses angegeben. Im zweiten Teil der Arbeit wird gezeigt, wie mit Hilfe dieses Prozesses der übergang von einem herk?mmlichen Bonus–Malus–System in der Kraftfahrthaftpflichtversicherung zu einem Bonus–Malus–System mit Berücksichtigung der Schadenart beschritten werden kann. Dazu wird zuerst eine Modellprüfung der gegebenen Daten vorgenommen und sodann werden für verschiedene mischende Verteilungen die Verteilungsparameter gesch?tzt und Nettopr?mien angegeben sowie die Prognosegenauigkeit getestet.
Summary: In this paper we show that the model of the bivariate mixed Poisson process arises in a natural way from the univariate mixed Poisson process, which is used in several areas for counting certain events. Furthermore we state some properties of the bivariate process. In the second part of the paper we illustrate how by means of the bivariate mixed Poisson process a bonus–malus system handling different types of accidents can be derived from the classical bonus–malus system in third–party liability insurance. To this end we first check the model on the given data and then estimate distribution parameters and compute net premiums for different mixing distributions as well as test the prediction probabilities.
* Vortrag am Dresdner Forum zur Versicherungsmathematik: Tarifierung in Erst- und Rückversicherung am 25. Juni 2004. Für die Unterstützung zu dieser Arbeit m?chte der Autor Lothar Partzsch, Klaus D. Schmidt (beide Dresden) und Friedemann Spies (München) recht herzlich danken.  相似文献   
30.
本文对系数全为多项式和广义多项式的n阶线性齐次微分方程引入特征方程的概念。给出了具有指数型解的充要条件,推广了经典的常系数线性方程和著名的Euler方程的的解法,为求解变系数线性微分方程提供了有效的方法。  相似文献   
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