细胞因子对运动训练的反应

从细胞因子的产生、作用特点及其对运动训练刺激所产生的生物学反应等方面。阐述了细胞因子对运动训练的反应受许多因素的影响，这一过程及其机制十分复杂．随着研究的深入，许多发现势必促使人们对运动损伤及其康复、运动与健康促进等一系列问题产生新的研究兴趣．     

Statistik für bivariate gemischte Poisson–Prozesse am Beispiel der Kraftfahrthaftpflichtversicherung

Zusammenfassung: In diesem Artikel wird der Weg von einem univariaten gemischten Poisson–Prozess, der in vielen Bereichen zum Z?hlen von Ereignissen benutzt wird, zu einem bivariaten gemischten Poisson–Prozess aufgezeigt. Dazu werden einige Eigenschaften des bivariaten Prozesses angegeben. Im zweiten Teil der Arbeit wird gezeigt, wie mit Hilfe dieses Prozesses der übergang von einem herk?mmlichen Bonus–Malus–System in der Kraftfahrthaftpflichtversicherung zu einem Bonus–Malus–System mit Berücksichtigung der Schadenart beschritten werden kann. Dazu wird zuerst eine Modellprüfung der gegebenen Daten vorgenommen und sodann werden für verschiedene mischende Verteilungen die Verteilungsparameter gesch?tzt und Nettopr?mien angegeben sowie die Prognosegenauigkeit getestet.

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Summary: In this paper we show that the model of the bivariate mixed Poisson process arises in a natural way from the univariate mixed Poisson process, which is used in several areas for counting certain events. Furthermore we state some properties of the bivariate process. In the second part of the paper we illustrate how by means of the bivariate mixed Poisson process a bonus–malus system handling different types of accidents can be derived from the classical bonus–malus system in third–party liability insurance. To this end we first check the model on the given data and then estimate distribution parameters and compute net premiums for different mixing distributions as well as test the prediction probabilities.

* Vortrag am Dresdner Forum zur Versicherungsmathematik: Tarifierung in Erst- und Rückversicherung am 25. Juni 2004. Für die Unterstützung zu dieser Arbeit m?chte der Autor Lothar Partzsch, Klaus D. Schmidt (beide Dresden) und Friedemann Spies (München) recht herzlich danken.     

雷诺润滑系统中的瞬态响应和稳定性分析

章建立了雷诺润滑系统中的流体瞬态压力方程和镜板的运动方程，分析了该系统的瞬态响应和相对阻尼系数以及特征值，结果表明，雷诺润滑系统不会处于负阻尼运动状态，且系统是稳定的。     

文学翻译的创造性叛逆与读者接受

文学翻译是译者在理解、解释原文基础上的创造性叛逆与读者对译文创造性叛逆的理解和反应的过程。文学翻译活动中的创造性叛逆的程度与可接受性必须以如下标准为依据:符合知识的客观性,符合理解的合理性、解释的普遍有效性,符合原文文本的定向性。     

关于外语专业题库建设范式的探讨

本文通过对当前国内外语教育形式的综览 ,指出了外语专业的题库建设已成为当务之急 ,并通过对各种考试形式的分析 ,提出了外语题库建设的具体理论模式———以项目反应理论为基础的计算机自适应测试。文章就有关方面的实施提出了自己的看法。     

Adaptive Management: A Paradigm for Remediation of Public Facilities Following a Terrorist Attack

Terrorist actions are aimed at maximizing harm (health, psychological, economical, and political) through the combined physical impacts of the act and fear. Immediate and effective response to a terrorist act is critical to limit human and environmental harm, effectively restore facility function, and maintain public confidence. Though there have been terrorist attacks in public facilities that we have learned from, overall our experiences in restoration of public facilities following a terrorist attack are limited. Restoration of public facilities following a release of a hazardous material is inherently far more complex than in industrial settings and has many unique technical, economic, social, and political challenges. For example, there may be a great need to quickly restore the facility to full operation and allow public access even though it was not designed for easy or rapid restoration, and critical information is needed for quantitative risk assessment and effective restoration must be anticipated to be incomplete and uncertain. Whereas present planning documents have substantial linearity in their organization, the “adaptive management” paradigm provides a constructive parallel paradigm for restoration of public facilities that anticipates and plans for uncertainty, inefficiencies, and stakeholder participation. Adaptive management grew out of the need to manage and restore natural resources in highly complex and changing environments with limited knowledge about causal relationships and responses to restoration actions. Similarities between natural resource management and restoration of a public facility after a terrorist attack suggest that integration of adaptive management principles explicitly into restoration processes will result in substantially enhanced and flexible responses necessary to meet the uncertainties of potential terrorist attacks.     

Predictive Bayesian Microbial Dose-Response Assessment Based on Suggested Self-Organization in Primary Illness Response: Cryptosporidium parvum

The probability of illness caused by very low doses of pathogens cannot generally be tested due to the numbers of subjects that would be needed, though such assessments of illness dose response are needed to evaluate drinking water standards. A predictive Bayesian dose-response assessment method was proposed previously to assess the unconditional probability of illness from available information and avoid the inconsistencies of confidence-based approaches. However, the method uses knowledge of the conditional dose-response form, and this form is not well established for the illness endpoint. A conditional parametric dose-response function for gastroenteric illness is proposed here based on simple numerical models of self-organized host-pathogen systems and probabilistic arguments. In the models, illnesses terminate when the host evolves by processes of natural selection to a self-organized critical value of wellness. A generalized beta-Poisson illness dose-response form emerges for the population as a whole. Use of this form is demonstrated in a predictive Bayesian dose-response assessment for cryptosporidiosis. Results suggest that a maximum allowable dose of 5.0 x 10(-7) oocysts/exposure (e.g., 2.5 x 10(-7) oocysts/L water) would correspond with the original goals of the U.S. Environmental Protection Agency Surface Water Treatment Rule, considering only primary illnesses resulting from Poisson-distributed pathogen counts. This estimate should be revised to account for non-Poisson distributions of Cryptosporidium parvum in drinking water and total response, considering secondary illness propagation in the population.     

一类变系数高阶线性齐次微分方程解的探求(英文)

本文对系数全为多项式和广义多项式的n阶线性齐次微分方程引入特征方程的概念。给出了具有指数型解的充要条件，推广了经典的常系数线性方程和著名的Euler方程的的解法，为求解变系数线性微分方程提供了有效的方法。     

带有快速反应策略供应链系统的补偿策略研究

过长的订购提前期往往使得零售商订货决策感到困难. 快速反应策略能使零售商在获 得更多更准确的市场需求信息后,调整订购量而提高收益. 但是快速反应策略并不一定使供应 商的利润也提高. 有文章指出只有低的服务水平才能使两者利润同时提高,因而这种方法在工 业应用中是不一定可行的. 补偿策略是一种广泛应用的方法,能够提高产品的客户服务水平, 因而研究了补偿策略在快速反应供应链系统中的作用. 在某些条件下,在快速反应供应链系统 中,补偿策略能使零售商与供应商一方的收益不变或者提高,另一方的收益有所提高,即Pare2 to 提高. 还研究了引进补偿策略后,供应链系统的最优解及期望卖出量、期望缺货量和期望残 余量的变化情况.     

Assessment of modeling longitudinal binary data based on graphical methods

Longitudinal categorical data are commonly applied in a variety of fields and are frequently analyzed by generalized estimating equation (GEE) method. Prior to making further inference based on the GEE model, the assessment of model fit is crucial. Graphical techniques have long been in widespread use for assessing the model adequacy. We develop alternative graphical approaches utilizing plots of marginal model-checking condition and local mean deviance to assess the GEE model with logit link for longitudinal binary responses. The applications of the proposed procedures are illustrated through two longitudinal binary datasets.