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81.
Low dose risk estimation via simultaneous statistical inferences 总被引:2,自引:0,他引:2
Walter W. Piegorsch R. Webster West Wei Pan Ralph L. Kodell 《Journal of the Royal Statistical Society. Series C, Applied statistics》2005,54(1):245-258
Summary. The paper develops and studies simultaneous confidence bounds that are useful for making low dose inferences in quantitative risk analysis. Application is intended for risk assessment studies where human, animal or ecological data are used to set safe low dose levels of a toxic agent, but where study information is limited to high dose levels of the agent. Methods are derived for estimating simultaneous, one-sided, upper confidence limits on risk for end points measured on a continuous scale. From the simultaneous confidence bounds, lower confidence limits on the dose that is associated with a particular risk (often referred to as a bench-mark dose ) are calculated. An important feature of the simultaneous construction is that any inferences that are based on inverting the simultaneous confidence bounds apply automatically to inverse bounds on the bench-mark dose. 相似文献
82.
中国货币政策和财政政策相对有效性的实证研究 总被引:1,自引:0,他引:1
在我国由计划经济向市场经济的体制转轨过程中,货币政策和财政政策已成为我国宏观经济调节的主要手段,在我国的经济发展中发挥了重要作用。但货币政策和财政政策是各自独立的政策体系,由于作用的方式和条件有较大区别,其效果也有较大不同,文章试图应用脉冲响应函数和方差分解方法,对改革开放以来我国货币政策和财政政策的效果进行实证比较研究,并得出有关结论,为我国的宏观调控政策提供理论分析和实证检验的依据。 相似文献
83.
Bayesian palaeoclimate reconstruction 总被引:1,自引:0,他引:1
J. Haslett M. Whiley S. Bhattacharya M. Salter-Townshend Simon P. Wilson J. R. M. Allen B. Huntley F. J. G. Mitchell 《Journal of the Royal Statistical Society. Series A, (Statistics in Society)》2006,169(3):395-438
Summary. We consider the problem of reconstructing prehistoric climates by using fossil data that have been extracted from lake sediment cores. Such reconstructions promise to provide one of the few ways to validate modern models of climate change. A hierarchical Bayesian modelling approach is presented and its use, inversely, is demonstrated in a relatively small but statistically challenging exercise: the reconstruction of prehistoric climate at Glendalough in Ireland from fossil pollen. This computationally intensive method extends current approaches by explicitly modelling uncertainty and reconstructing entire climate histories. The statistical issues that are raised relate to the use of compositional data (pollen) with covariates (climate) which are available at many modern sites but are missing for the fossil data. The compositional data arise as mixtures and the missing covariates have a temporal structure. Novel aspects of the analysis include a spatial process model for compositional data, local modelling of lattice data, the use, as a prior, of a random walk with long-tailed increments, a two-stage implementation of the Markov chain Monte Carlo approach and a fast approximate procedure for cross-validation in inverse problems. We present some details, contrasting its reconstructions with those which have been generated by a method in use in the palaeoclimatology literature. We suggest that the method provides a basis for resolving important challenging issues in palaeoclimate research. We draw attention to several challenging statistical issues that need to be overcome. 相似文献
84.
景美霞 《山西大同大学学报(社会科学版)》2009,23(3):101-102,112
过程写作法近年来盛行海外,已经成为西方写作教学主流。它将写作视为交互循环的心理认知过程和语言交际过程,重视写作的具体过程及其交际性,被证明对于提高学习者写作能力效果显著。本文系统地研究了过程写作法产生的背景、理论基础及其在写作教学中的实际应用。 相似文献
85.
Estimation of benchmark doses (BMDs) in quantitative risk assessment traditionally is based upon parametric dose‐response modeling. It is a well‐known concern, however, that if the chosen parametric model is uncertain and/or misspecified, inaccurate and possibly unsafe low‐dose inferences can result. We describe a nonparametric approach for estimating BMDs with quantal‐response data based on an isotonic regression method, and also study use of corresponding, nonparametric, bootstrap‐based confidence limits for the BMD. We explore the confidence limits’ small‐sample properties via a simulation study, and illustrate the calculations with an example from cancer risk assessment. It is seen that this nonparametric approach can provide a useful alternative for BMD estimation when faced with the problem of parametric model uncertainty. 相似文献
86.
This tutorial focuses on how to produce reliable and generalizable data from random‐digit‐dialing (RDD) landline and cell phone surveys. The article notes that RDD response rates have declined and explores the impact of this pronounced decline. The tutorial addresses order, response mode, and many other biases, sample size, cooperation and response rates, weighting, and hybrid designs‐all using examples from risk analysis to illustrate the key points. The article ends with a brief review of the advantages and disadvantages of major Internet and paper surveys tools, and how these can be molded and sometimes combined in repeated, longitudinal, and other designs to answer questions about risk preferences and perceptions. 相似文献
87.
对于所采集的条码图像,为了适应实时性的要求,以得到不同光照条件下的最佳阈值,该文提出了把直方图双峰法、OTSU法及NLNiblack阈值法结合起来的改进的自适应阈值法。实验证明了该方法具有高效性和稳定性。为了在条码分割图像中获取QR码的4个顶点,首先,根据3个位置探测图形的特性提出了一种新的方法以求取对应的3个顶点,同时利用QR码的特征提出挖空算法获取条码的边缘,再采用过已知点的Hough变换得到第4个顶点。实验证明该算法在各种采集条件下可有效地得到QR码的4个顶点。 相似文献
88.
介绍了在四川省第六届运动会上首次使用我们研制的中小型运动会实时处理和综合服务系统及其系统组成、功能特点及应用实况.该系统的主要特点是可靠性高、实时性好、功能强全、操作简便和经济实用. 相似文献
89.
ABSTRACTWeb surveys are an established data collection mode that use written language to provide information. The written language is accompanied by visual elements, such as presentation formats and shapes. However, research has shown that visual elements influence response behavior because respondents sometimes use interpretive heuristics to make sense of the visual elements. One such heuristic is the ‘left and top means first’ (LTMF) heuristic, which suggests that respondents tend to believe that a response scale consistently runs from left to right or from top to bottom. We conducted a web survey experiment to investigate how violations of the LTMF heuristic affect response behavior and data quality. For this purpose, a random half of respondents received response options that followed a consistent order and the other half received response options that followed an inconsistent order. The results reveal significantly different response distributions between the two groups. We also found that inconsistently ordered response options significantly increase response times and decrease data quality in terms of criterion validity. We, therefore, recommend using options that follow the design strategies of the LTMF heuristic. 相似文献
90.
AbstractConclusions of sample surveys dealing with matters of privacy are often disputed. Many people either refuse to participate or provide false answers. Indirect questioning techniques are designed so that reliable estimates can be produced while the privacy of the participants is protected. One such method, the Item Count Technique is gaining increasing popularity. However, the original version of the method does not fully protect the privacy of the participants. In this paper we propose a new version of the technique which better protects the privacy of the respondents and does not have the so-called floor and ceiling effects. 相似文献