泰乐松注射液的毒理学试验研究

为提供泰乐松注射液的安全性毒理学评价资料,本试验采用改进Karber法测定小鼠LD_(50);以剂量递增法测定小鼠蓄积性和耐受性;分别以剂量340、130、30mg／kg为3个试验组．设阴性和阳性对照组进行小鼠骨髓微核试验;分别以剂量500、250、120mg／kg为3个剂量组．设阴性和阳性对照组进行小鼠精于畸形试验。结果表明：其LD_(50)为669．80mg／kg,蓄积系数大于5．3,无明显蓄积毒性和耐受性（P＞0．05）,小鼠骨髓微核试验和精子畸形试验结果均为阴性。     

Sample selection in radiocarbon dating

Archaeologists working on the island of O'ahu, Hawai'i, use radiocarbon dating of samples of organic matter found trapped in fish-pond sediments to help them to learn about the chronology of the construction and use of the aquicultural systems created by the Polynesians. At one particular site, Loko Kuwili, 25 organic samples were obtained and funds were available to date an initial nine. However, on calibration to the calendar scale, the radiocarbon determinations provided date estimates that had very large variances. As a result, major issues of chronology remained unresolved and the archaeologists were faced with the prospect of another expensive programme of radiocarbon dating. This paper presents results of research that tackles the problems associated with selecting samples from those which are still available. Building on considerable recent research that utilizes Markov chain Monte Carlo methods to aid archaeologists in their radiocarbon calibration and interpretation, we adopt the standard Bayesian framework of risk functions, which allows us to assess the optimal samples to be sent for dating. Although rather computer intensive, our algorithms are simple to implement within the Bayesian radiocarbon framework that is already in place and produce results that are capable of direct interpretation by the archaeologists. By dating just three more samples from Loko Kuwili the expected variance on the date of greatest interest could be substantially reduced.     

我国上市公司独立审计质量的博弈模型刻画及其分析

本文分析了我国上市公司独立审计中会计师事务所、公司管理当局、独立董事、监管部门在审计行为中的博弈关系,应用博弈经济理论研究了在信息不对称条件下四方互动博弈策略的选择,并针对多方博弈的影响因素提出了提高独立审计质量的策略,以期对改进我国上市公司独立审计质量有所裨益.     

语言多属性决策的目标规划模型

研究了只有部分属性权重信息、属性值以语言变量或不确定语言变量形式给出且决策者对方案有偏好信息的语言多属性决策问题.给出了语言变量和不确定语言变量的运算法则,以及不确定语言变量之间比较的可能度公式,定义了语言变量的偏离度概念.在属性值以1)语言变量和2)不确定语言变量,这两种形式给出的情形下,分别建立了一个基于偏离度的目标规划模型,并通过求解这两种模型分别获得相应的属性权重.然后对于情形1),利用语言加权平均(LWA)算子,对语言决策信息进行加权集成,继而对方案进行排序和择优;对于情形2),利用不确定语言加权平均(ULWA)算子,对不确定语言决策信息进行加权集成,并利用可能度公式构造可能度矩阵(互补判断矩阵),继而利用互补判断矩阵排序公式对决策方案进行排序和择优.最后进行了实例分析.     

Testing Inference in Inflated Beta Regressions under Model Misspecification

We consider testing inference in inflated beta regressions subject to model misspecification. In particular, quasi-z tests based on sandwich covariance matrix estimators are described and their finite sample behavior is investigated via Monte Carlo simulations. The numerical evidence shows that quasi-z testing inference can be considerably more accurate than inference made through the usual z tests, especially when there is model misspecification. Interval estimation is also considered. We also present an empirical application that uses real (not simulated) data.     

大型低速重载径向动压轴承研究

为了开发大型贯流式水轮发电机组径向轴承,在试验台上采用了360的模型轴承对1740可倾6瓦块原型轴承进行模拟试验研究,最高试验比压3.37 MPa、最低线速度3.77 m/s、最高线速度22.62 m/s。试验表明:载荷、进油压力、转速、进油温度和安装间隙比等,对轴承油温升、油流量、功耗、瓦温及油膜厚度等都存在不同程度的影响,其中载荷和转速的影响比较显著。按照模型轴承指导设计的红岩子机组1740轴承已在电站可靠运行,同时开发了径向轴承热弹流计算程序,可以预测径向轴承的油膜压力、油膜温度、油膜厚度、损耗、流量等参数。     

Influence Diagnostics on Testing Linear Hypothesis in Linear Models with Correlated Errors

To assess the influence of observations on the parameter estimates, case deletion diagnostics are commonly used in linear regression models. For linear models with correlated errors we study the influence of observations on testing a linear hypothesis using single and multiple case deletions. The change in likelihood ratio test and F test theoretically is derived and it is shown these tests to be completely determined by two proposed generalized externally studentized residuals. An illustrative example of a real data set is also reported.     

An algorithm for maximum likelihood estimation in incomplete block variance component models

In the recovery of interblock information to improve the treatment differences estimates in incomplete block designs, the parameter p is usually unknown. Many authors have worked on the problem of estimating it and of studying its properties together with the properties of the treatment differences estimates. In this paper a numerically efficient algorithm is developed which yields the maximum likelihood estimates (MLE) of all the parameters in the mixed incomplete block design model (treatment effects, ρ and variance)     

水平井分段多簇压裂缝间干扰研究

水平井分段多簇压裂在现场得到了广泛运用，其压裂过程中普遍存在缝间干扰现象。缝间干扰有助于形成复 杂裂缝网络以提高储层导流能力，但是也会导致起裂困难，甚至形成砂堵。因此有必要对分段多簇压裂的缝间干扰问 题进行研究。对此，基于弹性力学建立了分析多簇裂缝诱导应力的数学模型，从起裂压力、裂缝宽度、簇间距等多方面 研究了缝间干扰对水平井分段多簇压裂施工的影响。模拟结果显示，诱导应力会导致起裂压力升高、裂缝变窄，严重 时将造成压裂施工失败。通过进行分析，给出了起裂过程及延伸过程中缝间干扰的影响关系。分析认为，利用缝间干 扰提高改造体积时应当控制簇间距防止对压裂施工造成负面影响。研究结论对优化水平井分段多簇压裂设计具有指 导意义。     

An M/G/1 clearing queueing system with setup time and multiple vacations for an unreliable server

This paper studies an M/G/1 clearing queueing system with setup time and multiple vacations, in which all present customers in the system are served simultaneously and breakdowns may occur in busy or setup period. We investigate the stationary distribution of system size and the Laplace–Stieltjes transform of sojourn time. In addition, various performance measures are discussed, such as the mean system size at arbitrary time and the mean length of a vacation circle. Moreover, a cost analysis is carried out for this queueing system. Numerical results are presented to study the sensitivity of the system parameters on the expected cost function and system performances.