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71.
针对传统众数估计值会因为组距的改变而不稳定,在已有的半极差(样本)众数估计方法上,提出多比例极差(样本)众数估计新方法。模拟研究显示,相对于半极差(样本)众数估计方法,该方法估计结果更稳定、准确。在实证分析中,基于2014、2015年国家一体化住户调查数据,使用新方法计算了新疆兵团居民人均可支配收入众数。结果表明,众数可以作为居民人均可支配收入平均数、中位数的有益补充,众数在政府统计中的推广及应用具有一定的可行性与必要性。 相似文献
72.
Bayesian adaptive dose‐escalation designs for simultaneously estimating the optimal and maximum safe dose based on safety and efficacy
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Wai Yin Yeung Bruno Reigner Ulrich Beyer Cheikh Diack Daniel Sabanés bové Giuseppe Palermo Thomas Jaki 《Pharmaceutical statistics》2017,16(6):396-413
The main purpose of dose‐escalation trials is to identify the dose(s) that is/are safe and efficacious for further investigations in later studies. In this paper, we introduce dose‐escalation designs that incorporate both the dose‐limiting events and dose‐limiting toxicities (DLTs) and indicative responses of efficacy into the procedure. A flexible nonparametric model is used for modelling the continuous efficacy responses while a logistic model is used for the binary DLTs. Escalation decisions are based on the combination of the probabilities of DLTs and expected efficacy through a gain function. On the basis of this setup, we then introduce 2 types of Bayesian adaptive dose‐escalation strategies. The first type of procedures, called “single objective,” aims to identify and recommend a single dose, either the maximum tolerated dose, the highest dose that is considered as safe, or the optimal dose, a safe dose that gives optimum benefit risk. The second type, called “dual objective,” aims to jointly estimate both the maximum tolerated dose and the optimal dose accurately. The recommended doses obtained under these dose‐escalation procedures provide information about the safety and efficacy profile of the novel drug to facilitate later studies. We evaluate different strategies via simulations based on an example constructed from a real trial on patients with type 2 diabetes, and the use of stopping rules is assessed. We find that the nonparametric model estimates the efficacy responses well for different underlying true shapes. The dual‐objective designs give better results in terms of identifying the 2 real target doses compared to the single‐objective designs. 相似文献
73.
岳翔 《淮海工学院学报(社会科学版)》2013,(8):69-71
老年人、青年人、儿童多代合居的家庭,因生活方式的差异致使传统的卫浴空间设计显现出诸多问题。在空间规划、设施配置、氛围营造三个方面引入通用设计理念,合理设计卫浴空间使合居家庭的生活更加融洽。 相似文献
74.
N. Mukhopadhyay 《统计学通讯:理论与方法》2013,42(8):2471-2506
The literature on sequential estimation problems for negative exponential populations has been reviewed here, We attempt to bring in all the published and unpublished materials known to us in a fairly coherent fashion. Both the concepts and theoretical findings are discussed. 相似文献
75.
《Journal of Technology in Human Services》2013,31(4):23-39
ABSTRACT A usability test of a distance continuing education website for human service professionals is discussed. The website's purpose was to help meet the continuing education needs of human service professionals in a largely rural Midwestern state. The purpose of the usability evaluation was to assess the website's ease of use, efficiency, and user satisfaction in a representative sample of human service professionals. Users completed eleven basic search tasks with the site and report their impressions of the information presented. In addition, performance data including success, time on task, and efficiency were gathered. Implications of user satisfaction and performance data highlight the importance of stakeholder's involvement in the early stages of website design. 相似文献
76.
In this article, we propose a general method for testing the Granger noncausality hypothesis in stationary nonlinear models of unknown functional form. These tests are based on a Taylor expansion of the nonlinear model around a given point in the sample space. We study the performance of our tests by a Monte Carlo experiment and compare these to the most widely used linear test. Our tests appear to be well-sized and have reasonably good power properties. 相似文献
77.
Software packages usually report the results of statistical tests using p-values. Users often interpret these values by comparing them with standard thresholds, for example, 0.1, 1, and 5%, which is sometimes reinforced by a star rating (***, **, and *, respectively). We consider an arbitrary statistical test whose p-value p is not available explicitly, but can be approximated by Monte Carlo samples, for example, by bootstrap or permutation tests. The standard implementation of such tests usually draws a fixed number of samples to approximate p. However, the probability that the exact and the approximated p-value lie on different sides of a threshold (the resampling risk) can be high, particularly for p-values close to a threshold. We present a method to overcome this. We consider a finite set of user-specified intervals that cover [0, 1] and that can be overlapping. We call these p-value buckets. We present algorithms that, with arbitrarily high probability, return a p-value bucket containing p. We prove that for both a bounded resampling risk and a finite runtime, overlapping buckets need to be employed, and that our methods both bound the resampling risk and guarantee a finite runtime for such overlapping buckets. To interpret decisions with overlapping buckets, we propose an extension of the star rating system. We demonstrate that our methods are suitable for use in standard software, including for low p-value thresholds occurring in multiple testing settings, and that they can be computationally more efficient than standard implementations. 相似文献
78.
自动化立体仓库中出入库任务顺序与出库位置选择集成优化研究 总被引:1,自引:0,他引:1
具有多个出口的自动化立体仓库系统是一种将存储和分拣相结合的新型仓储技术,其最典型的特征是在货架底层有很多个出库位置以供取货人员分拣。研究此系统中出入库任务排序与出口选择的集成优化问题,以最小化堆垛机完成所有任务的移动距离为目标,将此问题转化为一个混合整数规划模型。根据问题的特点设计了两阶段启发式算法求解此问题,数值结果表明设计的算法能在较短时间内给出近似最优解,同时与企业常用的先到先服务方法相比,该算法可以缩短超过20%的移动距离。 相似文献
79.
会计信息披露是企业向信息使用者揭示和反映企业价值运动,高质量的信息披露可以降低信息不对称程度,使投资者能更正确地做出判断.以生物医药业上市公司为例,采用Logistic回归分析方法,系统研究公司治理与会计信息的披露质量之间的关系,发现公司治理中的董事会规模、独立董事比例和监事会规模的提高会使得会计信息披露质量得到提高,董事会会议次数与会计信息披露质量显著负相关. 相似文献
80.
面对资本市场风险加剧的现实背景,以"公司经营业绩与股票市场业绩一致趋优"为稳健型投资的核心要素,立足于区间数据表示、会计信息度量两个关键要素,开展稳健型股票价值投资的多准则决策建模研究。面向稳健型投资决策目标,提出满足"稳健性""局部性""全局性"3个特性的序化机理,围绕关键特征选择、特征评价、全序化建模的主体脉络建立系统性多准则决策方法,进而构建"稳健型股票价值投资决策"的研究框架。 相似文献