Using intersection matrices to identify graphical structure

Intersection matrices help identify the common graphical structure of two or more objects. They arise naturally in a variety of settings. Several examples of their use in a computer algebra environment are given. These include: simplifying an expression involving array products, automating cumulant calculations, determining the behaviour of an expected value operator and identifying model hierarchy in a factorial experiment. The emphasis is placed on the graphical structure, and the symmetry of arrays help reduce the complexity of the graphical problem.     

Csiszar’s ϕ-divergences for testing the order in a Markov chain

x ₁, ..., x _n+r can be treated as the sample values of a Markov chain of order r or less (chain in which the dependence extends over r+1 consecutive variables only), and consider the problem of testing the hypothesis H ₀ that a chain of order r− 1 will be sufficient on the basis of the tools given by the Statistical Information Theory: _ϕ-Divergences. More precisely, if p _{a 1 ....., a r}: _{a r +1} denotes the transition probability for a r ^th order Markov chain, the hypothesis to be tested is H ₀:p _{a 1 ....., a r}: _{a r +1} = p _{a 2 ....., a r}: _{a r +1}, a _i ∈{1, ..., s}, i = 1, ..., r + 1 The tests given in this paper, for the first time, will have as a particular case the likelihood ratio test and the test based on the chi-squared statistic. Received: August 3, 1998; revised version: November 25, 1999     

Evaluating surrogate variables for improving microarray multiple testing inference

The use of surrogate variables has been proposed as a means to capture, for a given observed set of data, sources driving the dependency structure among high-dimensional sets of features and remove the effects of those sources and their potential negative impact on simultaneous inference. In this article we illustrate the potential effects of latent variables on testing dependence and the resulting impact on multiple inference, we briefly review the method of surrogate variable analysis proposed by Leek and Storey (PNAS 2008; 105:18718-18723), and assess that method via simulations intended to mimic the complexity of feature dependence observed in real-world microarray data. The method is also assessed via application to a recent Merck microarray data set. Both simulation and case study results indicate that surrogate variable analysis can offer a viable strategy for tackling the multiple testing dependence problem when the features follow a potentially complex correlation structure, yielding improvements in the variability of false positive rates and increases in power.     

Simultaneous semi-sequential testing of dual alternatives for pattern recognition

In this paper, we propose a new nonparametric simultaneous test for dual alternatives. Simultaneous tests for dual alternatives are used for pattern detection of arsenic contamination level in ground water. We consider two possible patterns, namely, monotone shift and an umbrella-type location alternative, as the dual alternatives. Pattern recognition problems of this nature are addressed in Bandyopadhyay et al. [5], stretching the idea of multiple hypotheses tests as in Benjamini and Hochberg [6]. In the present context, we develop an alternative approach based on contrasts that helps us to detect three underlying pattern much more efficiently. We illustrate the new methodology through a motivating example related to highly sensitive issue of arsenic contamination in ground water. We provide some Monte-Carlo studies related to the proposed technique and give a comparative study between different detection procedures. We also obtain some related asymptotic results.     

Testing the equality among distribution functions from independent and right censored samples via Cramér–von Mises criterion

The traditional Cramér–von Mises criterion is used in order to develop a test to compare the equality of the underlying lifetime distributions in the presence of independent censoring times. Its asymptotic distribution is proved and a resampling plan, which is valid for unbalanced data situations, is proposed. Its statistical power is studied and compared with commonly used linear rank tests by Monte Carlo simulations and a real data analysis is also considered. It is observed that the new test is clearly more powerful than the traditional ones when there exists no uniform dominance among involved distributions and in the presence of late differences. Its statistical power is also good in the other considered scenarios.     

Generalized Augmentation to Control the False Discovery Exceedance in Multiple Testing

Abstract.  A new multiple testing procedure, the generalized augmentation procedure (GAUGE), is introduced. The procedure is shown to control the false discovery exceedance and to be competitive in terms of power. It is also shown how to apply the idea of GAUGE to achieve control of other error measures. Extensions to dependence are discussed, together with a modification valid under arbitrary dependence. We present an application to an original study on prostate cancer and on a benchmark data set on colon cancer.     

Testing for cointegration at any frequency using spectral methods

Summary In this paper a new simple test for cointegration at any frequency is presented. This method can thus be applied to test for cointegration both at the zero and at the seasonal frequencies. It requires the estimation of the coherency spectrum of weakly stationary processes, therefore only standard spectral theory is involved. The testing procedure is similar to the one suggested by Phillips and Ouliaris (1988) and recently generalized by Joyeux (1992) to frequencies different from zero, but it does not suffer of some problems connected with the use of principal components methods in the frequency domain. Invited paper at the Conference held in Bologna, Italy, 27–28 May 1993, on ?Statistical Tests: Methodology and Econometric Applications?.     

我国企业多元化投资决策的反思

企业多元化经营战备是当今世界许多大中型企业的一种战备选择。我国的一些大企业近年来也走上了多元化经营的道路 ,但多数都身陷困境或遭受失败 ,主要是由于多元化投资决策失误所致。因此 ,深入探讨多元化投资的理论和战略 ,对我国一些大中型企业来说 ,就显得十分重要。     

Divergence-based estimation and testing with misclassified data

The well-known chi-squared goodness-of-fit test for a multinomial distribution is generally biased when the observations are subject to misclassification. In Pardo and Zografos (2000) the problem was considered using a double sampling scheme and ø-divergence test statistics. A new problem appears if the null hypothesis is not simple because it is necessary to give estimators for the unknown parameters. In this paper the minimum ø-divergence estimators are considered and some of their properties are established. The proposed ø-divergence test statistics are obtained by calculating ø-divergences between probability density functions and by replacing parameters by their minimum ø-divergence estimators in the derived expressions. Asymptotic distributions of the new test statistics are also obtained. The testing procedure is illustrated with an example.     

Outlier detection by robust principal components analysis

The robust principal components analysis (RPCA) introduced by Campbell (Applied Statistics 1980, 29, 231–237) provides in addition to robust versions of the usual output of a principal components analysis, weights for the contribution of each point to the robust estimation of each component. Low weights may thus be used to indicate outliers. The present simulation study provides critical values for testing the kth smallest weight in the RPCA of a sample of n p-dimensional vectors, under the null hypothesis of a multivariate normal distribution. The cases p=2(2)10, 15, 20 for n=20, 30, 40, 50, 75, 100 subject to n≥p/2, are examined, with k≤√n.