Semiparametric Global Cross-ratio Models for Bivariate Censored Data

Abstract.  Multivariate correlated failure time data arise in many medical and scientific settings. In the analysis of such data, it is important to use models where the parameters have simple interpretations. In this paper, we formulate a model for bivariate survival data based on the Plackett distribution. The model is an alternative to the Gamma frailty model proposed by Clayton and Oakes. The parameter in this distribution has a very appealing odds ratio interpretation for dependence between the two failure times; in addition, it allows for negative dependence. We develop novel semiparametric estimation and inference procedures for the model. The asymptotic results of the estimator are developed. The performance of the proposed techniques in finite samples is examined using simulation studies; in addition, the proposed methods are applied to data from an observational study in cancer.     

Maximum Likelihood Estimation in Gaussian Chain Graph Models under the Alternative Markov Property

Abstract.  The Andersson–Madigan–Perlman (AMP) Markov property is a recently proposed alternative Markov property (AMP) for chain graphs. In the case of continuous variables with a joint multivariate Gaussian distribution, it is the AMP rather than the earlier introduced Lauritzen–Wermuth–Frydenberg Markov property that is coherent with data-generation by natural block-recursive regressions. In this paper, we show that maximum likelihood estimates in Gaussian AMP chain graph models can be obtained by combining generalized least squares and iterative proportional fitting to an iterative algorithm. In an appendix, we give useful convergence results for iterative partial maximization algorithms that apply in particular to the described algorithm.     

Identifiability of Finite Mixtures of Elliptical Distributions

Abstract.  We present general results on the identifiability of finite mixtures of elliptical distributions under conditions on the characteristic generators or density generators. Examples include the multivariate t -distribution, symmetric stable laws, exponential power and Kotz distributions. In each case, the shape parameter is allowed to vary in the mixture, in addition to the location vector and the scatter matrix. Furthermore, we discuss the identifiability of finite mixtures of elliptical densities with generators that correspond to scale mixtures of normal distributions.     

Maximum-likelihood estimates and likelihood-ratio criteria for multivariate elliptically contoured distributions

For a class of multivariate elliptically contoured distributions the maximum-likelihood estimators of the mean vector and covariance matrix are found under certain conditions. Likelihood-ratio criteria are obtained for a class of null hypotheses. These have the same form as in the normal case.     

RECURSIVE RESIDUALS FOR MULTIVARIATE REGRESSION MODELS

Recursive residuals and their relationship to the recursive estimation of regression parameters have been developed for unvaried regression mod els. Such residuals and estimates have been used to test the constancy of regression over time. The current paper extends this work to multivariate regression modal.     

ROBUST ESTIMATION UNDER TYPE II CENSORING

The properties of robust M-estimators with type II censored failure time data are considered. The optimal members within two classes of ψ-functions are characterized. The first optimality result is the censored data analogue of the optimality result described in Hampel et al. (1986); the estimators corresponding to the optimal members within this class are referred to as the optimal robust estimators. The second result pertains to a restricted class of ψ-functions which is the analogue of the class of ψ-functions considered in James (1986) for randomly censored data; the estimators corresponding to the optimal members within this restricted class are referred to as the optimal James-type estimators. We examine the usefulness of the two classes of ψ-functions and find that the breakdown point and efficiency of the optimal James-type estimators compare favourably with those of the corresponding optimal robust estimators. From the computational point of view, the optimal James-type ψ-functions are readily obtainable from the optimal ψ-functions in the uncensored case. The ψ-functions for the optimal robust estimators require a separate algorithm which is provided. A data set illustrates the optimal robust estimators for the parameters of the extreme value distribution.     

Expert Judgment-Based Risk Assessment Using Statistical Scenario Analysis: A Case Study—Running the Bulls in Pamplona (Spain)

In this article, we present a methodology to assess the risk incurred by a participant in an activity involving danger of injury. The lack of high-quality historical data for the case considered prevented us from constructing a sufficiently detailed statistical model. It was therefore decided to generate a risk assessment model based on expert judgment. The methodology is illustrated in a real case context: the assessment of risk to participants in a San Fermin bull-run in Pamplona (Spain). The members of the panel of "experts on the bull-run" represented very different perspectives on the phenomenon: runners, surgeons and other health care personnel, journalists, civil defense workers, security staff, organizers, herdsmen, authors of books on the bull-run, etc. We consulted 55 experts. Our methodology includes the design of a survey instrument to elicit the experts' views and the statistical and mathematical procedures used to aggregate their subjective opinions.     

QUALITY CONTROL WITH MULTIVARIATE DATA

The paper examines statistical process control of bivariate and multivariate data, using in particular the multivariate equivalents of the univariate Shewhart chart, CUSUM chart and the Exponentially Weighted Moving Average chart. This illustrates the usefulness of Principal Component methods in statistical process control with multivariate data.     

Tests for the multivariate two-sample problem based on empirical probability measures

Nonparametric tests are proposed for the equality of two unknown p-variate distributions. Empirical probability measures are defined from samples from the two distributions and used to construct test statistics as the supremum of the absolute differences between empirical probabilities, the supremum being taken over all possible events. The test statistics are truly multivariate in not requiring the artificial ranking of multivariate observations, and they are distribution-free in the general p-variate case. Asymptotic null distributions are obtained. Powers of the proposed tests and a competitor are examined by Monte Carlo techniques.     

Recursive estimation of the mode of a multivariate density

Let f be an unknown possibly multimodal density on R^d and let X₁, X₂, … be a sequence of independent random vectors with density f. Several recursive estimates of the mode of f are proposed, and sufficient conditions ensuring their weak and strong consistency are established.