股指期货的设计分析

股指期货最主要的功能是套期保值、回避系统性风险。为了达到上述目的,在设计股票指数时要保证指数的代表性、敏感性,同时避免指数被操纵。在设计期货合约时要恰当地设计合约价值,保证合约的流动性;要合理地确定结算价,避免因合约设计的不合理而出现操纵行为。     

魏晋南北朝御苑禊赏景观探析

以禊赏为主题的园林艺术创作始自魏晋。禊赏源于原始的巫祭性祓禊,至魏晋时期,衍为高度审美化的文化盛事,进而被纳入皇家园林,引发了一系列园林新景观的创作。结合对魏晋禊赏文化内涵的挖掘,剖析了御苑禊赏景观在时代性审美观的推动下,由浩大铺张向简约写意的演变过程;揭示了文化意趣对建筑创作的巨大影响力,以为今人之鉴。     

Comparison of design for quadratic regression on cubes

Designs for quadratic regression are considered when the possible choices of the controllable variable are points x=(x₁,x₂,…,x_q) in the q-dimensional cube of side 2. The designs that are optimum with respect to such criteria as those of D-, A-, and E-optimality are compared in their performance relative to these and other criteria. Some of the results are developed algebraically; others, numerically. The possible supports of E-optimum designs are much more numerous than the D-optimum supports characterized earlier. The A-optimum design appears to be fairly robust in its efficiency, under variation of criterion.     

Tables of Cyclic Incomplete Block Designs: r=k

Initial blocks and efficiencies are given for cyclic incomplete block designs in the range t= 10(1)60 and r=k= 3(1)10. The designs have been selected by search procedures using optimality criteria which maximize the efficiency factor.     

Clinical Trials of Drugs Used Off-Label in Neonates: Ethical Issues and Alternative Study Designs

The use of drugs for indications unapproved by the Food and Drug Administration (FDA), often called “off-label use,” is widespread in children, including neonates. The widespread off-label use of drugs in neonates presents ethical and safety challenges. Since the passage of the Best Pharmaceuticals for Children Act (BPCA) in 2002, both the FDA and National Institutes of Health (NIH) have taken initiatives to facilitate and encourage research to achieve the necessary labeling for drugs routinely used in infants and children. Federal regulations provide broad rules and guidance for the protection of human subjects in research. However, there are ethical issues that a physician may face when designing clinical trials of drugs in neonates that are routinely used off-label and widely believed to be beneficial. We attempt to describe these ethical challenges and provide recommendations, including alternative study designs, to resolve them in an ethical framework that takes into account the Belmont Report, the statement of the World Medical Association (WMA), and federal regulations.     

Single-Case Evaluation Designs for Practitioners

ABSTRACT

This article examines single-case designs that omit baseline phases, contain shorter reversal phases, administer treatment across fewer baselines, or have other features that make them easier for practitioners to use in evaluating their own interventions. Particular attention is given to the Repeated Pretest-Posttest and the Periodic Treatments Designs, the Nonconcurrent Multiple-Baseline Design, the short reversal design, the short multiple-baseline design, and the short alternating treatments design. Also discussed and illustrated is how these streamlined designs can raise practitioners' sensitivity to intervention outcomes, assist practitioners in providing evidence-based services while adjusting for client diversity, and advance practitioners' knowledge.     

On Some Two- and Three-dimensional D-minimax Designs for Estimating Slopes of a Third-order Response Surface

Design of experiments is considered for the situation where estimation of the slopes of a response surface is the main interest. Under the D-minimax criterion, the objective is to minimize the generalized variance of the estimated axial slopes at a point maximized over all points in the region of interest in the factor space. For the third-order model over spherical regions, the D-minimax designs are derived in two and three dimensions. The efficiencies of some two- and three-dimensional designs available in the literature are also investigated.     

Asymptotic properties of maximum quasi-likelihood estimators in generalized linear models with adaptive designs

In this paper, we present the asymptotic properties of maximum quasi-likelihood estimators (MQLEs) in generalized linear models with adaptive designs under some mild regular conditions. The existence of MQLEs in quasi-likelihood equation is discussed. The rate of convergence and asymptotic normality of MQLEs are also established. The results are illustrated by Monte-Carlo simulations.     

Some remarks on experimental design for estimating the expectation of a stationary random process

For estimation of the mean of a stationary random process the variance-optimal choice of the observation points (the so called experimental design) is considered. For this discrete and continuous designs are introduced, some known results of process statistics are interpreted to experimental design and a proposal for simplification of the minimization problem is offered, moreover it is proved, that for monotone decreasing eovarianee functions a design, for which the points near the ends of the observation interval are more dense than in the middle, is better than the equidistant design.