Estimating the propagation rate of a viral infection of potato plants via mixtures of regressions

A problem arising from the study of the spread of a viral infection among potato plants by aphids appears to involve a mixture of two linear regressions on a single predictor variable. The plant scientists studying the problem were particularly interested in obtaining a 95% confidence upper bound for the infection rate. We discuss briefly the procedure for fitting mixtures of regression models by means of maximum likelihood, effected via the EM algorithm. We give general expressions for the implementation of the M-step and then address the issue of conducting statistical inference in this context. A technique due to T. A. Louis may be used to estimate the covariance matrix of the parameter estimates by calculating the observed Fisher information matrix. We develop general expressions for the entries of this information matrix. Having the complete covariance matrix permits the calculation of confidence and prediction bands for the fitted model. We also investigate the testing of hypotheses concerning the number of components in the mixture via parametric and 'semiparametric' bootstrapping. Finally, we develop a method of producing diagnostic plots of the residuals from a mixture of linear regressions.     

Standard errors for EM estimation

The EM algorithm is a popular method for computing maximum likelihood estimates. One of its drawbacks is that it does not produce standard errors as a by-product. We consider obtaining standard errors by numerical differentiation. Two approaches are considered. The first differentiates the Fisher score vector to yield the Hessian of the log-likelihood. The second differentiates the EM operator and uses an identity that relates its derivative to the Hessian of the log-likelihood. The well-known SEM algorithm uses the second approach. We consider three additional algorithms: one that uses the first approach and two that use the second. We evaluate the complexity and precision of these three and the SEM in algorithm seven examples. The first is a single-parameter example used to give insight. The others are three examples in each of two areas of EM application: Poisson mixture models and the estimation of covariance from incomplete data. The examples show that there are algorithms that are much simpler and more accurate than the SEM algorithm. Hopefully their simplicity will increase the availability of standard error estimates in EM applications. It is shown that, as previously conjectured, a symmetry diagnostic can accurately estimate errors arising from numerical differentiation. Some issues related to the speed of the EM algorithm and algorithms that differentiate the EM operator are identified.     

信用风险中回收率分布的双Beta模型

本文研究了随机回收率的分布,建立了回收率的双Beta分布密度模型,它具有双峰分布的特点,这与Moody公司的最新研究相吻合,弥补了现有回收率分布模型均为单峰的不足。利用基于数论网格的序贯优化算法对所建模型的参数做出了估计,借助于核密度估计的工具,进行了实证分析,结果表明双Beta模型的拟合误差很小,远小于Beta模型的误差,它是表示回收率理想的模型。最后给出了抽取双Beta分布随机数的方法。     

Fitting competing risks data to bivariate Pareto models

This paper revisits two bivariate Pareto models for fitting competing risks data. The first model is the Frank copula model, and the second one is a bivariate Pareto model introduced by Sankaran and Nair (1993 Sankaran, P. G., and N. U. Nair. 1993. A bivariate Pareto model and its applications to reliability. Naval Research Logistics 40 (7):1013–1020. doi:10.1002/1520-6750(199312)40:7%3c1013::AID-NAV3220400711%3e3.0.CO;2-7.[Crossref], [Web of Science ®] , [Google Scholar]). We discuss the identifiability issues of these models and develop the maximum likelihood estimation procedures including their computational algorithms and model-diagnostic procedures. Simulations are conducted to examine the performance of the maximum likelihood estimation. Real data are analyzed for illustration.     

Implementing Monte Carlo tests with p-value buckets

Software packages usually report the results of statistical tests using p-values. Users often interpret these values by comparing them with standard thresholds, for example, 0.1, 1, and 5%, which is sometimes reinforced by a star rating (***, **, and *, respectively). We consider an arbitrary statistical test whose p-value p is not available explicitly, but can be approximated by Monte Carlo samples, for example, by bootstrap or permutation tests. The standard implementation of such tests usually draws a fixed number of samples to approximate p. However, the probability that the exact and the approximated p-value lie on different sides of a threshold (the resampling risk) can be high, particularly for p-values close to a threshold. We present a method to overcome this. We consider a finite set of user-specified intervals that cover [0, 1] and that can be overlapping. We call these p-value buckets. We present algorithms that, with arbitrarily high probability, return a p-value bucket containing p. We prove that for both a bounded resampling risk and a finite runtime, overlapping buckets need to be employed, and that our methods both bound the resampling risk and guarantee a finite runtime for such overlapping buckets. To interpret decisions with overlapping buckets, we propose an extension of the star rating system. We demonstrate that our methods are suitable for use in standard software, including for low p-value thresholds occurring in multiple testing settings, and that they can be computationally more efficient than standard implementations.     

Penalized proportion estimation for non parametric mixture of regressions

Abstract

In this article, we propose a penalized local log-likelihood method to locally select the number of components in non parametric finite mixture of regression models via proportion shrinkage method. Mean functions and variance functions are estimated simultaneously. We show that the number of components can be estimated consistently, and further establish asymptotic normality of functional estimates. We use a modified EM algorithm to estimate the unknown functions. Simulations are conducted to demonstrate the performance of the proposed method. We illustrate our method via an empirical analysis of the housing price index data of United States.     

Symmetrical Design of Experiment in Global Sensitivity Analysis Based on ANOVA High-dimensional Model Representation

This article reviews symmetrical global sensitivity analysis based on the analysis of variance of high-dimensional model representation. To overcome the computational difficulties and explore the use of symmetrical design of experiment (SDOE), two methods are presented. If the form of the objective function f is known, we use SDOE to estimate the symmetrical global sensitivity indices instead of Monte Carlo or quasi-Monte Carlo simulation. Otherwise, we use the observed values of the experiment to do symmetrical global sensitivity analysis. These methods are easy to implement and can reduce the computational cost. An example is given by symmetrical design of experiment.     

Goodness-of-fit tests of generalized linear mixed models for repeated ordinal responses

Categorical longitudinal data are frequently applied in a variety of fields, and are commonly fitted by generalized linear mixed models (GLMMs) and generalized estimating equations models. The cumulative logit is one of the useful link functions to deal with the problem involving repeated ordinal responses. To check the adequacy of the GLMMs with cumulative logit link function, two goodness-of-fit tests constructed by the unweighted sum of squared model residuals using numerical integration and bootstrap resampling technique are proposed. The empirical type I error rates and powers of the proposed tests are examined by simulation studies. The ordinal longitudinal studies are utilized to illustrate the application of the two proposed tests.     

Inference on a progressive type I interval-censored truncated normal distribution

In this paper, we consider the problem of making statistical inference for a truncated normal distribution under progressive type I interval censoring. We obtain maximum likelihood estimators of unknown parameters using the expectation-maximization algorithm and in sequel, we also compute corresponding midpoint estimates of parameters. Estimation based on the probability plot method is also considered. Asymptotic confidence intervals of unknown parameters are constructed based on the observed Fisher information matrix. We obtain Bayes estimators of parameters with respect to informative and non-informative prior distributions under squared error and linex loss functions. We compute these estimates using the importance sampling procedure. The highest posterior density intervals of unknown parameters are constructed as well. We present a Monte Carlo simulation study to compare the performance of proposed point and interval estimators. Analysis of a real data set is also performed for illustration purposes. Finally, inspection times and optimal censoring plans based on the expected Fisher information matrix are discussed.     

Approximate composite marginal likelihood inference in spatial generalized linear mixed models

Non-Gaussian spatial responses are usually modeled using spatial generalized linear mixed model with spatial random effects. The likelihood function of this model cannot usually be given in a closed form, thus the maximum likelihood approach is very challenging. There are numerical ways to maximize the likelihood function, such as Monte Carlo Expectation Maximization and Quadrature Pairwise Expectation Maximization algorithms. They can be applied but may in such cases be computationally very slow or even prohibitive. Gauss–Hermite quadrature approximation only suitable for low-dimensional latent variables and its accuracy depends on the number of quadrature points. Here, we propose a new approximate pairwise maximum likelihood method to the inference of the spatial generalized linear mixed model. This approximate method is fast and deterministic, using no sampling-based strategies. The performance of the proposed method is illustrated through two simulation examples and practical aspects are investigated through a case study on a rainfall data set.