Measurement error in regression analysis

Consider the linear regression model Y = Xθ+ ε where Y denotes a vector of n observations on the dependent variable, X is a known matrix, θ is a vector of parameters to be estimated and e is a random vector of uncorrelated errors. If X'X is nearly singular, that is if the smallest characteristic root of X'X s small then a small perurbation in the elements of X, such as due to measurement errors, induces considerable variation in the least squares estimate of θ. In this paper we examine for the asymptotic case when n is large the effect of perturbation with regard to the bias and mean squared error of the estimate.     

Improved deviance goodness of fit statistics for a gamma regression model

A gamma regression model with an exponential link function for the means Is considered. Moment properties of the deviance statistics based on maximum likelihood and weighted least squares fits are used to define modified deviance statistics which provide alternative global goodness of fit tests. The null distribution properties of the deviances and modified deviances are compared with those of the approximating chi-square distribution and It is shown that the use of the modified deviances gives much better control over the significance levels of the tests.     

Projectors and linear estimation in general linear models

The paper gives a self-contained account of minimum disper­sion linear unbiased estimation of the expectation vector in a linear model with the dispersion matrix belonging to some, rather arbitrary, set of nonnegative definite matrices. The approach to linear estimation in general linear models recommended here is a direct generalization of some ideas and results presented by Rao (1973, 19 74) for the case of a general Gauss-Markov model

A new insight into the nature of some estimation problems originaly arising in the context of a general Gauss-Markov model as well as the correspondence of results known in the literature to those obtained in the present paper for general linear models are also given. As preliminary results the theory of projectors defined by Rao (1973) is extended.     

Experimental designs and their efficiencies for spatially correlated observations in two dimensions

Optimality of experimental designs for spatially correlated observations is investigated.come two dimensional correlation structures are discussed and an attempt has been made to find optimal or nearly optimal design for each sitution.The solution lend to designs similar to that used for repeated measurements.The relative efficiency of the proposed designs in comparison to randomized latin square designs is tabulated for some cases.     

Distribution theory and inference for polynomial-normal densities

This paper considers a class of densities formed by taking the product of nonnegative polynomials and normal densities. These densities provide a rich class of distributions that can be used in modelling when faced with non-normal characteristics such as skewness and multimodality. In this paper we address inferential and computational issues arising in the practical implementation of this parametric family in the context of the linear model. Exact results are recorded for the conditional analysis of location-scale models and an importance sampling algorithm is developed for the implementation of a conditional analysis for the general linear model when using polynomial-normal distributions for the error.     

Multiple deletion measures and conditional influence in regression model

The joint effect of the deletion of the ith and jih cases is given by Gray and Ling (1984), they discussed the influence measures for influential subsets in linear regression analysis. The present paper is concerned with multiple sets of deletion measures in the linear regression model. In particular we are interested in the effects of the jointly and conditional influence analysis for the detection of two influential subsets.     

Optimal non-diagonal-type estimators in linear regression under the prediction error sum of squares criterion

This article considers the notion of the non-diagonal-type estimator (NDTE) under the prediction error sum of squares (PRESS) criterion. First, the optimal NDTE in the PRESS sense is derived theoretically and applied to the cosmetics sales data. Second, we make a further study to extend the NDTE to the general case of the covariance matrix of the model and then give a Bayesian explanation for this extension. Third, two remarks concerned with some potential shortcomings of the NDTE are presented and an alternative solution is provided and illustrated by means of simulations.     

Covariate Selection for the Semiparametric Additive Risk Model

Abstract.  This paper considers covariate selection for the additive hazards model. This model is particularly simple to study theoretically and its practical implementation has several major advantages to the similar methodology for the proportional hazards model. One complication compared with the proportional model is, however, that there is no simple likelihood to work with. We here study a least squares criterion with desirable properties and show how this criterion can be interpreted as a prediction error. Given this criterion, we define ridge and Lasso estimators as well as an adaptive Lasso and study their large sample properties for the situation where the number of covariates p is smaller than the number of observations. We also show that the adaptive Lasso has the oracle property. In many practical situations, it is more relevant to tackle the situation with large p compared with the number of observations. We do this by studying the properties of the so-called Dantzig selector in the setting of the additive risk model. Specifically, we establish a bound on how close the solution is to a true sparse signal in the case where the number of covariates is large. In a simulation study, we also compare the Dantzig and adaptive Lasso for a moderate to small number of covariates. The methods are applied to a breast cancer data set with gene expression recordings and to the primary biliary cirrhosis clinical data.     

ROC Curves in Non‐Parametric Location‐Scale Regression Models

Abstract. The receiver operating characteristic (ROC) curve is a tool of extensive use to analyse the discrimination capability of a diagnostic variable in medical studies. In certain situations, the presence of a covariate related to the diagnostic variable can increase the discriminating power of the ROC curve. In this article, we model the effect of the covariate over the diagnostic variable by means of non‐parametric location‐scale regression models. We propose a new non‐parametric estimator of the conditional ROC curve and study its asymptotic properties. We also present some simulations and an illustration to a data set concerning diagnosis of diabetes.