Implementing particle swarm optimization algorithm to estimate the mixture of two Weibull parameters with censored data

We present the maximum likelihood estimation (MLE) via particle swarm optimization (PSO) algorithm to estimate the mixture of two Weibull parameters with complete and multiple censored data. A simulation study is conducted to assess the performance of the MLE via PSO algorithm, quasi-Newton method and expectation-maximization (EM) algorithm for different parameter settings and sample sizes in both uncensored and censored cases. The simulation results showed that the PSO algorithm outperforms the quasi-Newton method and the EM algorithm in most cases regarding bias and root mean square errors. Two numerical examples are used to demonstrate the performance of our proposed method.     

Comparing diagnostic tests: test of hypothesis for likelihood ratios

Likelihood ratios (LRs) are used to characterize the efficiency of diagnostic tests. In this paper, we use the classical weighted least squares (CWLS) test procedure, which was originally used for testing the homogeneity of relative risks, for comparing the LRs of two or more binary diagnostic tests. We compare the performance of this method with the relative diagnostic likelihood ratio (rDLR) method and the diagnostic likelihood ratio regression (DLRReg) approach in terms of size and power, and we observe that the performances of CWLS and rDLR are the same when used to compare two diagnostic tests, while DLRReg method has higher type I error rates and powers. We also examine the performances of the CWLS and DLRReg methods for comparing three diagnostic tests in various sample size and prevalence combinations. On the basis of Monte Carlo simulations, we conclude that all of the tests are generally conservative and have low power, especially in settings of small sample size and low prevalence.     

Rank invariant tests with left truncated and interval censored data

Peto and Peto (1972) have studied rank invariant tests to compare two survival curves for right censored data. We apply their tests, including the logrank test and the generalized Wilcoxon test, to left truncated and interval censored data. The significance levels of the tests are approximated by Monte Carlo permutation tests. Simulation studies are conducted to show their size and power under different distributional differences. In particular, the logrank test works well under the Cox proportional hazards alternatives, as for the usual right censored data. The methods are illustrated by the analysis of the Massachusetts Health Care Panel Study dataset.     

Parameter identification for the discretely observed geometric fractional Brownian motion

This paper deals with the problem of estimating all the unknown parameters of geometric fractional Brownian processes from discrete observations. The estimation procedure is built upon the marriage of the quadratic variation and the maximum likelihood approach. The asymptotic properties of the estimators are provided. Moveover, we compare our derived method with the approach proposed by Misiran et al. [Fractional Black-Scholes models: complete MLE with application to fractional option pricing. In International conference on optimization and control; Guiyang, China; 2010. p. 573–586.], namely the complete maximum likelihood estimation. Simulation studies confirm theoretical findings and illustrate that our methodology is efficient and reliable. To show how to apply our approach in realistic contexts, an empirical study of Chinese financial market is also presented.     

Local estimation for varying-coefficient models with longitudinal data

Varying-coefficient models are very useful for longitudinal data analysis. In this paper, we focus on varying-coefficient models for longitudinal data. We develop a new estimation procedure using Cholesky decomposition and profile least squares techniques. Asymptotic normality for the proposed estimators of varying-coefficient functions has been established. Monte Carlo simulation studies show excellent finite-sample performance. We illustrate our methods with a real data example.     

On the existence of maximum likelihood estimates for weighted logistic regression

The problems of existence and uniqueness of maximum likelihood estimates for logistic regression were completely solved by Silvapulle in 1981 and Albert and Anderson in 1984. In this paper, we extend the well-known results by Silvapulle and by Albert and Anderson to weighted logistic regression. We analytically prove the equivalence between the overlap condition used by Albert and Anderson and that used by Silvapulle. We show that the maximum likelihood estimate of weighted logistic regression does not exist if there is a complete separation or a quasicomplete separation of the data points, and exists and is unique if there is an overlap of data points. Our proofs and results for weighted logistic apply to unweighted logistic regression.     

The exponential–Weibull lifetime distribution

In this paper, we propose a new three-parameter model called the exponential–Weibull distribution, which includes as special models some widely known lifetime distributions. Some mathematical properties of the proposed distribution are investigated. We derive four explicit expressions for the generalized ordinary moments and a general formula for the incomplete moments based on infinite sums of Meijer's G functions. We also obtain explicit expressions for the generating function and mean deviations. We estimate the model parameters by maximum likelihood and determine the observed information matrix. Some simulations are run to assess the performance of the maximum likelihood estimators. The flexibility of the new distribution is illustrated by means of an application to real data.     

Generalizing the standardized hazard ratio to multivariate proportional hazards regression,with an application to clinical~genomic studies

The standardized hazard ratio for univariate proportional hazards regression is generalized as a scalar to multivariate proportional hazards regression. Estimators of the standardized log hazard ratio are developed, with corrections for bias and for regression to the mean in high-dimensional analyses. Tests of point and interval null hypotheses and confidence intervals are constructed. Cohort sampling study designs, commonly used in prospective–retrospective clinical genomic studies, are accommodated.     

Alternative estimators in logistic regression when the data are collinear

Logistic regression using conditional maximum likelihood estimation has recently gained widespread use. Many of the applications of logistic regression have been in situations in which the independent variables are collinear. It is shown that collinearity among the independent variables seriously effects the conditional maximum likelihood estimator in that the variance of this estimator is inflated in much the same way that collinearity inflates the variance of the least squares estimator in multiple regression. Drawing on the similarities between multiple and logistic regression several alternative estimators, which reduce the effect of the collinearity and are easy to obtain in practice, are suggested and compared in a simulation study.     

Testing for a change point in a sequence of exponential random variables with repeated values

Two test statistics are proposed for the change-point problem with repeated values when the data follow an exponential distribution. The properties of these two statistics have been studied and their asymptotic distributions under the alternative have been derived. The powers of the two test statistics are compared. Real-data examples are presented to illustrate the application of these tests.