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41.
If the unknown mean of a univariate population is sufficiently close to the value of an initial guess then an appropriate shrinkage estimator has smaller average squared error than the sample mean. This principle has been known for some time, but it does not appear to have found extension to problems of interval estimation. The author presents valid two‐sided 95% and 99% “shrinkage” confidence intervals for the mean of a normal distribution. These intervals are narrower than the usual interval based on the Student distribution when the population mean lies in such an “effective interval.” A reduction of 20% in the mean width of the interval is possible when the population mean is sufficiently close to the value of the guess. The author also describes a modification to existing shrinkage point estimators of the general univariate mean that enables the effective interval to be enlarged.  相似文献   
42.
In this paper, we present a general formulation of an algorithm, the adaptive independent chain (AIC), that was introduced in a special context in Gåsemyr et al . [ Methodol. Comput. Appl. Probab. 3 (2001)]. The algorithm aims at producing samples from a specific target distribution Π, and is an adaptive, non-Markovian version of the Metropolis–Hastings independent chain. A certain parametric class of possible proposal distributions is fixed, and the parameters of the proposal distribution are updated periodically on the basis of the recent history of the chain, thereby obtaining proposals that get ever closer to Π. We show that under certain conditions, the algorithm produces an exact sample from Π in a finite number of iterations, and hence that it converges to Π. We also present another adaptive algorithm, the componentwise adaptive independent chain (CAIC), which may be an alternative in particular in high dimensions. The CAIC may be regarded as an adaptive approximation to the Gibbs sampler updating parametric approximations to the conditionals of Π.  相似文献   
43.
Summary.  The paper considers the problem of estimating the entire temperature field for every location on the globe from scattered surface air temperatures observed by a network of weather-stations. Classical methods such as spherical harmonics and spherical smoothing splines are not efficient in representing data that have inherent multiscale structures. The paper presents an estimation method that can adapt to the multiscale characteristics of the data. The method is based on a spherical wavelet approach that has recently been developed for a multiscale representation and analysis of scattered data. Spatially adaptive estimators are obtained by coupling the spherical wavelets with different thresholding (selective reconstruction) techniques. These estimators are compared for their spatial adaptability and extrapolation performance by using the surface air temperature data.  相似文献   
44.
Modeling for Risk Assessment of Neurotoxic Effects   总被引:2,自引:0,他引:2  
The regulation of noncancer toxicants, including neurotoxicants, has usually been based upon a reference dose (allowable daily intake). A reference dose is obtained by dividing a no-observed-effect level by uncertainty (safety) factors to account for intraspecies and interspecies sensitivities to a chemical. It is assumed that the risk at the reference dose is negligible, but no attempt generally is made to estimate the risk at the reference dose. A procedure is outlined that provides estimates of risk as a function of dose. The first step is to establish a mathematical relationship between a biological effect and the dose of a chemical. Knowledge of biological mechanisms and/or pharmacokinetics can assist in the choice of plausible mathematical models. The mathematical model provides estimates of average responses as a function of dose. Secondly, estimates of risk require selection of a distribution of individual responses about the average response given by the mathematical model. In the case of a normal or lognormal distribution, only an estimate of the standard deviation is needed. The third step is to define an adverse level for a response so that the probability (risk) of exceeding that level can be estimated as a function of dose. Because a firm response level often cannot be established at which adverse biological effects occur, it may be necessary to at least establish an abnormal response level that only a small proportion of individuals would exceed in an unexposed group. That is, if a normal range of responses can be established, then the probability (risk) of abnormal responses can be estimated. In order to illustrate this process, measures of the neurotransmitter serotonin and its metabolite 5-hydroxyindoleacetic acid in specific areas of the brain of rats and monkeys are analyzed after exposure to the neurotoxicant methylene-dioxymethamphetamine. These risk estimates are compared with risk estimates from the quantal approach in which animals are classified as either abnormal or not depending upon abnormal serotonin levels.  相似文献   
45.
Some statistical models defined in terms of a generating stochastic mechanism have intractable distribution theory, which renders parameter estimation difficult. However, a Monte Carlo estimate of the log-likelihood surface for such a model can be obtained via computation of nonparametric density estimates from simulated realizations of the model. Unfortunately, the bias inherent in density estimation can cause bias in the resulting log-likelihood estimate that alters the location of its maximizer. In this paper a methodology for radically reducing this bias is developed for models with an additive error component. An illustrative example involving a stochastic model of molecular fragmentation and measurement is given.  相似文献   
46.
Abstract.  The likelihood ratio statistic for testing pointwise hypotheses about the survival time distribution in the current status model can be inverted to yield confidence intervals (CIs). One advantage of this procedure is that CIs can be formed without estimating the unknown parameters that figure in the asymptotic distribution of the maximum likelihood estimator (MLE) of the distribution function. We discuss the likelihood ratio-based CIs for the distribution function and the quantile function and compare these intervals to several different intervals based on the MLE. The quantiles of the limiting distribution of the MLE are estimated using various methods including parametric fitting, kernel smoothing and subsampling techniques. Comparisons are carried out both for simulated data and on a data set involving time to immunization against rubella. The comparisons indicate that the likelihood ratio-based intervals are preferable from several perspectives.  相似文献   
47.
本文整合社会网络理论、注意力基础观和新制度主义理论等,通过对282家制造企业的问卷调查,采用多元回归分析方法,探讨了网络密度和高管注意力配置的交互匹配对企业绿色创新的影响机制,以及制度压力在其中的调节作用。研究发现,在高密度网络中,高管采用注意力聚集策略对绿色创新有显著正向影响;而在低密度网络中,高管采用注意力分散策略对绿色创新有显著正向影响。规制压力和模仿压力均正向调节网络密度和高管注意力配置的交互作用对绿色创新的影响,但模仿压力的调节作用更强。通过构建不同制度压力情景下网络密度与高管注意力的交互作用对绿色创新影响的理论框架,本文推动社会网络理论、注意力基础观等成熟的理论成果从一般创新向绿色创新研究领域繁衍,为企业绿色创新加入与主流理论的对话做了努力,为企业在绿色创新过程中根据不同的制度压力,以及所嵌入的组织间网络密度情况,选择合适的注意力配置策略提供理论参考。  相似文献   
48.
针对过度旅游对旅游目的地造成紊乱的问题,对过度旅游的成因及危害进行总结分析,利用统计数据确定综合旅游密度、旅游强度、民宿密度3项判断过度旅游状态的指标,并将3项指标分数之和作为评价过度旅游的指标值; 使用Zipf分布双对数图与H/T断裂点法确定数据等级划分方式,采用定距分数累加方式建立过度旅游综合评价方法; 利用国内外代表性旅游城市的数据进行了实证分析,验证了所建立综合评价方法的可行性。研究认为,过度旅游综合评价分数给出了旅游目的地过度旅游程度的相对顺序,能够推测各样本过度旅游风险所对应的要素,为制定过度旅游对应政策的优先级提供参考; 在样本城市中,国外过度旅游目的地注重流量管控、征收旅游税等三四级对策,而中国过度旅游目的地注重景区保护和流量管控等二三级对策,尽管国内样本城市旅游服务负荷已高于部分发达国家,但未出现排斥游客的过度旅游现象; 国内仍需要利用经济手段避免部分地区的旅游业依赖,升级城市景区保护为城市全域保护,适时推进旅游税政策。  相似文献   
49.
Summary Letg(x) andf(x) be continuous density function on (a, b) and let {ϕj} be a complete orthonormal sequence of functions onL 2(g), which is the set of squared integrable functions weighted byg on (a, b). Suppose that over (a, b). Given a grouped sample of sizen fromf(x), the paper investigates the asymptotic properties of the restricted maximum likelihood estimator of density, obtained by setting all but the firstm of the ϑj’s equal to0. Practical suggestions are given for performing estimation via the use of Fourier and Legendre polynomial series. Research partially supported by: CNR grant, n. 93. 00837. CT10.  相似文献   
50.
The standard approach to non-parametric bivariate density estimation is to use a kernel density estimator. Practical performance of this estimator is hindered by the fact that the estimator is not adaptive (in the sense that the level of smoothing is not sensitive to local properties of the density). In this paper a simple, automatic and adaptive bivariate density estimator is proposed based on the estimation of marginal and conditional densities. Asymptotic properties of the estimator are examined, and guidance to practical application of the method is given. Application to two examples illustrates the usefulness of the estimator as an exploratory tool, particularly in situations where the local behaviour of the density varies widely. The proposed estimator is also appropriate for use as a pilot estimate for an adaptive kernel estimate, since it is relatively inexpensive to calculate.  相似文献   
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