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361.
In the design of control charts, it is usually assumed that process parameters are known. However, in many practical applications the values of these parameters are unknown and should be estimated using historical in-control process observations. In this study, the performance of adaptive c-chart with estimated parameter is evaluated. It is demonstrated that by increasing the size and the number of samples in estimating the process parameter, the performance of the chart converges to that of the known parameter case. Finally the best phase I sampling scenarios are presented to make the chart with the estimated parameter perform as well as the chart with the known parameter.  相似文献   
362.
Randomized clinical trials with count measurements as the primary outcome are common in various medical areas such as seizure counts in epilepsy trials, or relapse counts in multiple sclerosis trials. Controlled clinical trials frequently use a conventional parallel-group design that assigns subjects randomly to one of two treatment groups and repeatedly evaluates them at baseline and intervals across a treatment period of a fixed duration. The primary interest is to compare the rates of change between treatment groups. Generalized estimating equations (GEEs) have been widely used to compare rates of change between treatment groups because of its robustness to misspecification of the true correlation structure. In this paper, we derive a sample size formula for comparing the rates of change between two groups in a repeatedly measured count outcome using GEE. The sample size formula incorporates general missing patterns such as independent missing and monotone missing, and general correlation structures such as AR(1) and compound symmetry (CS). The performance of the sample size formula is evaluated through simulation studies. Sample size estimation is illustrated by a clinical trial example from epilepsy.  相似文献   
363.
A bivariate stochastic volatility model is employed to measure the effect of intervention by the Bank of Japan (BOJ) on daily returns and volume in the USD/YEN foreign exchange market. Missing observations are accounted for, and a data-based Wishart prior for the precision matrix of the errors to the transition equation that is in line with the likelihood is suggested. Empirical results suggest there is strong conditional heteroskedasticity in the mean-corrected volume measure, as well as contemporaneous correlation in the errors to both the observation and transition equations. A threshold model is used for the BOJ reaction function, which is estimated jointly with the bivariate stochastic volatility model via Markov chain Monte Carlo. This accounts for endogeneity between volatility in the market and the BOJ reaction function, something that has hindered much previous empirical analysis in the literature on central bank intervention. The empirical results suggest there was a shift in behavior by the BOJ, with a movement away from a policy of market stabilization and toward a role of support for domestic monetary policy objectives. Throughout, we observe “leaning against the wind” behavior, something that is a feature of most previous empirical analysis of central bank intervention. A comparison with a bivariate EGARCH model suggests that the bivariate stochastic volatility model produces estimates that better capture spikes in in-sample volatility. This is important in improving estimates of a central bank reaction function because it is at these periods of high daily volatility that central banks more frequently intervene.  相似文献   
364.
Data‐analytic tools for models other than the normal linear regression model are relatively rare. Here we develop plots and diagnostic statistics for nonconstant variance for the random‐effects model (REM). REMs for longitudinal data include both within‐ and between‐subject variances. A basic assumption is that the two variance terms are constant across subjects. However, we often find that these variances are functions of covariates, and the data set has what we call explainable heterogeneity, which needs to be allowed for in the model. We characterize several types of heterogeneity of variance in REMs and develop three diagnostic tests using the score statistic: one for each of the two variance terms, and the third for a form of multivariate nonconstant variance. For each test we present an adjusted residual plot which can identify cases that are unusually influential on the outcome of the test.  相似文献   
365.
本文提出一种基于Mealy自动机的多人重复博弈演化模型。该模型用Mealy自动机表示博弈参与人的战略行为,并构造一个基于遗传算法的自动机演化程序。博弈初始时,博弈参与人提交一个Mealy自动机。博弈参与人的有限自动机在当前状态下与竞争对手的自动机进行博弈,并且依据其获取的支付转换到下一状态,然后在新的状态下开始新一周期的博弈。在进行一段时间博弈后,则利用自动机演化程序对自动机进行演化,演化的标准是依据其在这一段时间博弈中的获得的平均支付及战略成本。通过仿真可以验证,在参与人理性程度较低且存在信息干扰的情况下,博弈参与人为了降低在博弈过程中的信息失真率,战略成本需要以较大的幅度下降。  相似文献   
366.
Patient dropout is a common problem in studies that collect repeated binary measurements. Generalized estimating equations (GEE) are often used to analyze such data. The dropout mechanism may be plausibly missing at random (MAR), i.e. unrelated to future measurements given covariates and past measurements. In this case, various authors have recommended weighted GEE with weights based on an assumed dropout model, or an imputation approach, or a doubly robust approach based on weighting and imputation. These approaches provide asymptotically unbiased inference, provided the dropout or imputation model (as appropriate) is correctly specified. Other authors have suggested that, provided the working correlation structure is correctly specified, GEE using an improved estimator of the correlation parameters (‘modified GEE’) show minimal bias. These modified GEE have not been thoroughly examined. In this paper, we study the asymptotic bias under MAR dropout of these modified GEE, the standard GEE, and also GEE using the true correlation. We demonstrate that all three methods are biased in general. The modified GEE may be preferred to the standard GEE and are subject to only minimal bias in many MAR scenarios but in others are substantially biased. Hence, we recommend the modified GEE be used with caution.  相似文献   
367.
区域经济协调发展是中国经济社会发展的一个重要原则。当前区域经济发展中存在的竞争性趋同及重复投资等现象普遍存在,通过博弈分析发现产生这种现象的根本原因为区域竞争博弈的短期行为和区域主体考核制度的单一。通过假设,利用模型分别模拟计算了各种状态下的收益,利用合作博弈模型探索了区域长期合作需要满足的条件,验证了在资源禀赋存在差异的情况下打造"经济圈"是最优的政策选择,从而避免竞争性趋同,克服区域政府的短期行为,实现协同发展。  相似文献   
368.
Most theoretical or applied research on repeated games with imperfect monitoring has focused on public strategies: strategies that depend solely on the history of publicly observable signals. This paper sheds light on the role of private strategies: strategies that depend not only on public signals, but also on players' own actions in the past. Our main finding is that players can sometimes make better use of information by using private strategies and that efficiency in repeated games can be improved. Our equilibrium private strategy for repeated prisoners' dilemma games consists of two states and has the property that each player's optimal strategy is independent of the other player's state.  相似文献   
369.
A new approach is presented for testing independence in contingency tables with clustered observations. The approach is based on the framework of generalized linear mixed models. Under the multinomial logistic link function, the category counts are modelled with random cluster effects and a modified likelihood ratio statistic is used for testing independence. The method is applicable to multi-way tables, and can accommodate multiple levels of clustering. It is illustrated using a benchmark dataset.  相似文献   
370.
Clustered longitudinal data feature cross‐sectional associations within clusters, serial dependence within subjects, and associations between responses at different time points from different subjects within the same cluster. Generalized estimating equations are often used for inference with data of this sort since they do not require full specification of the response model. When data are incomplete, however, they require data to be missing completely at random unless inverse probability weights are introduced based on a model for the missing data process. The authors propose a robust approach for incomplete clustered longitudinal data using composite likelihood. Specifically, pairwise likelihood methods are described for conducting robust estimation with minimal model assumptions made. The authors also show that the resulting estimates remain valid for a wide variety of missing data problems including missing at random mechanisms and so in such cases there is no need to model the missing data process. In addition to describing the asymptotic properties of the resulting estimators, it is shown that the method performs well empirically through simulation studies for complete and incomplete data. Pairwise likelihood estimators are also compared with estimators obtained from inverse probability weighted alternating logistic regression. An application to data from the Waterloo Smoking Prevention Project is provided for illustration. The Canadian Journal of Statistics 39: 34–51; 2011 © 2010 Statistical Society of Canada  相似文献   
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