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81.
Lixin Meng 《Journal of Statistical Computation and Simulation》2017,87(1):88-99
Ordinary differential equations (ODEs) are normally used to model dynamic processes in applied sciences such as biology, engineering, physics, and many other areas. In these models, the parameters are usually unknown, and thus they are often specified artificially or empirically. Alternatively, a feasible method is to estimate the parameters based on observed data. In this study, we propose a Bayesian penalized B-spline approach to estimate the parameters and initial values for ODEs used in epidemiology. We evaluated the efficiency of the proposed method based on simulations using the Markov chain Monte Carlo algorithm for the Kermack–McKendrick model. The proposed approach is also illustrated based on a real application to the transmission dynamics of hepatitis C virus in mainland China. 相似文献
82.
Small area statistics obtained from sample survey data provide a critical source of information used to study health, economic, and sociological trends. However, most large-scale sample surveys are not designed for the purpose of producing small area statistics. Moreover, data disseminators are prevented from releasing public-use microdata for small geographic areas for disclosure reasons; thus, limiting the utility of the data they collect. This research evaluates a synthetic data method, intended for data disseminators, for releasing public-use microdata for small geographic areas based on complex sample survey data. The method replaces all observed survey values with synthetic (or imputed) values generated from a hierarchical Bayesian model that explicitly accounts for complex sample design features, including stratification, clustering, and sampling weights. The method is applied to restricted microdata from the National Health Interview Survey and synthetic data are generated for both sampled and non-sampled small areas. The analytic validity of the resulting small area inferences is assessed by direct comparison with the actual data, a simulation study, and a cross-validation study. 相似文献
83.
Yi Zhang 《统计学通讯:理论与方法》2018,47(2):415-426
In this article, we propose the non parametric mixture of strictly monotone regression models. For implementation, a two-step procedure is derived. We further establish the asymptotic normality of the resultant estimator and demonstrate its good performance through numerical examples. 相似文献
84.
Fengkai Yang 《统计学通讯:模拟与计算》2017,46(8):5861-5878
In this article, a non-iterative posterior sampling algorithm for linear quantile regression model based on the asymmetric Laplace distribution is proposed. The algorithm combines the inverse Bayes formulae, sampling/importance resampling, and the expectation maximization algorithm to obtain independently and identically distributed samples approximately from the observed posterior distribution, which eliminates the convergence problems in the iterative Gibbs sampling and overcomes the difficulty in evaluating the standard deviance in the EM algorithm. The numeric results in simulations and application to the classical Engel data show that the non-iterative sampling algorithm is more effective than the Gibbs sampling and EM algorithm. 相似文献
85.
Frailty models are used in the survival analysis to account for the unobserved heterogeneity in the individual risks to disease and death. To analyze the bivariate data on related survival times (e.g., matched pairs experiments, twin or family data), the shared frailty models were suggested. In this article, we introduce the shared gamma frailty models with the reversed hazard rate. We develop the Bayesian estimation procedure using the Markov chain Monte Carlo (MCMC) technique to estimate the parameters involved in the model. We present a simulation study to compare the true values of the parameters with the estimated values. We apply the model to a real life bivariate survival dataset. 相似文献
86.
Mixed-Weibull distribution has been used to model a wide range of failure data sets, and in many practical situations the number of components in a mixture model is unknown. Thus, the parameter estimation of a mixed-Weibull distribution is considered and the important issue of how to determine the number of components is discussed. Two approaches are proposed to solve this problem. One is the method of moments and the other is a regularization type of fuzzy clustering algorithm. Finally, numerical examples and two real data sets are given to illustrate the features of the proposed approaches. 相似文献
87.
There are a number of statistical techniques for analysing epidemic outbreaks. However, many diseases are endemic within populations and the analysis of such diseases are complicated by changing population demography. Motivated by the spread of cowpox among rodent populations, a combined mathematical model for population and disease dynamics is introduced. An MCMC algorithm is then constructed to make statistical inference for the model based on data being obtained from a capture–recapture experiment. The statistical analysis is used to identify the key elements in the spread of the cowpox virus. 相似文献
88.
Xiaofeng Steven Liu 《统计学通讯:模拟与计算》2013,42(6):1433-1436
This short article shows an unified approach to representing and computing the cumulative distribution function for noncentral t, F, and χ2. Unlike the existing algorithms, which involve different expansion and/or recurrence, the new approach consistently represents all the three noncentral cumulative distribution functions as the integral of the normal cumulative distribution function and χ2 density function. 相似文献
89.
Clustering Algorithms are nowadays really important tools in microarray data analysis. The different clustering algorithm generally used in biological science does not take into consideration the underlying probability distribution of the data. In this sense, they are heuristic in nature. In this work we proposed a clustering algorithm based on EM Algorithm. It gives 28% less misclassification than the K-means algorithm (which is mostly use in Bio science). We have also shown on a real data set that this algorithm can be efficiently used for detecting the genes which are responsible for a particular disease. 相似文献
90.
Since multi-attribute control charts have received little attention compared with multivariate variable control charts, this research is concerned with developing a new methodology to employ the multivariate exponentially weighted moving average (MEWMA) charts for m-attribute binomial processes; the attributes being the number of nonconforming items. Moreover, since the variable sample size and sampling interval (VSSI) MEWMA charts detect small process mean shifts faster than the traditional MEWMA, an economic design of the VSSI MEWMA chart is proposed to obtain the optimum design parameters of the chart. The sample size, the sampling interval, and the warning/action limit coefficients are obtained using a genetic algorithm such that the expected total cost per hour is minimized. At the end, a sensitivity analysis has been carried out to investigate the effects of the cost and the model parameters on the solution of the economic design of the VSSI MEWMA chart. 相似文献