Local estimation for varying-coefficient models with longitudinal data

Varying-coefficient models are very useful for longitudinal data analysis. In this paper, we focus on varying-coefficient models for longitudinal data. We develop a new estimation procedure using Cholesky decomposition and profile least squares techniques. Asymptotic normality for the proposed estimators of varying-coefficient functions has been established. Monte Carlo simulation studies show excellent finite-sample performance. We illustrate our methods with a real data example.     

On the existence of maximum likelihood estimates for weighted logistic regression

The problems of existence and uniqueness of maximum likelihood estimates for logistic regression were completely solved by Silvapulle in 1981 and Albert and Anderson in 1984. In this paper, we extend the well-known results by Silvapulle and by Albert and Anderson to weighted logistic regression. We analytically prove the equivalence between the overlap condition used by Albert and Anderson and that used by Silvapulle. We show that the maximum likelihood estimate of weighted logistic regression does not exist if there is a complete separation or a quasicomplete separation of the data points, and exists and is unique if there is an overlap of data points. Our proofs and results for weighted logistic apply to unweighted logistic regression.     

Robust sparse regression and tuning parameter selection via the efficient bootstrap information criteria

There is currently much discussion about lasso-type regularized regression which is a useful tool for simultaneous estimation and variable selection. Although the lasso-type regularization has several advantages in regression modelling, owing to its sparsity, it suffers from outliers because of using penalized least-squares methods. To overcome this issue, we propose a robust lasso-type estimation procedure that uses the robust criteria as the loss function, imposing L₁-type penalty called the elastic net. We also introduce to use the efficient bootstrap information criteria for choosing optimal regularization parameters and a constant in outlier detection. Simulation studies and real data analysis are given to examine the efficiency of the proposed robust sparse regression modelling. We observe that our modelling strategy performs well in the presence of outliers.     

Generalizing the standardized hazard ratio to multivariate proportional hazards regression,with an application to clinical~genomic studies

The standardized hazard ratio for univariate proportional hazards regression is generalized as a scalar to multivariate proportional hazards regression. Estimators of the standardized log hazard ratio are developed, with corrections for bias and for regression to the mean in high-dimensional analyses. Tests of point and interval null hypotheses and confidence intervals are constructed. Cohort sampling study designs, commonly used in prospective–retrospective clinical genomic studies, are accommodated.     

Alternative estimators in logistic regression when the data are collinear

Logistic regression using conditional maximum likelihood estimation has recently gained widespread use. Many of the applications of logistic regression have been in situations in which the independent variables are collinear. It is shown that collinearity among the independent variables seriously effects the conditional maximum likelihood estimator in that the variance of this estimator is inflated in much the same way that collinearity inflates the variance of the least squares estimator in multiple regression. Drawing on the similarities between multiple and logistic regression several alternative estimators, which reduce the effect of the collinearity and are easy to obtain in practice, are suggested and compared in a simulation study.     

An adaptive two-sample location-scale test of lepage type for symmetric distributions

For the two-sample location and scale problem we propose an adaptive test which is based on so called Lepage type tests. The well known test of Lepage (1971) is a combination of the Wilcoxon test for location alternatives and the Ansari-Bradley test for scale alternatives and it behaves well for symmetric and medium-tailed distributions. For the cae of short-, medium- and long-tailed distributions we replace the Wilcoxon test and the .Ansari-Bradley test by suitable other two-sample tests for location and scale, respectively, in oder to get higher power than the classical Lepage test for such distribotions. These tests here are called Lepage type tests. in practice, however, we generally have no clear idea about the distribution having generated our data. Thus, an adaptive test should be applied which takes the the given data set inio consideration. The proposed adaptive test is based on the concept of Hogg (1974), i.e., first, to classify the unknown symmetric distribution function with respect to a measure for tailweight and second, to apply an appropriate Lepage type test for this classified type of distribution. We compare the adaptive test with the three Lepage type tests in the adaptive scheme and with the classical Lepage test as well as with other parametric and nonparametric tests. The power comparison is carried out via Monte Carlo simulation. It is shown that the adaptive test is the best one for the broad class of distributions considered.     

Bivariate symbolic regression models for interval-valued variables

Interval-valued variables have become very common in data analysis. Up until now, symbolic regression mostly approaches this type of data from an optimization point of view, considering neither the probabilistic aspects of the models nor the nonlinear relationships between the interval response and the interval predictors. In this article, we formulate interval-valued variables as bivariate random vectors and introduce the bivariate symbolic regression model based on the generalized linear models theory which provides much-needed exibility in practice. Important inferential aspects are investigated. Applications to synthetic and real data illustrate the usefulness of the proposed approach.     

Bootstrap methods for bias correction and confidence interval estimation for nonlinear quantile regression of longitudinal data

This paper examines the use of bootstrapping for bias correction and calculation of confidence intervals (CIs) for a weighted nonlinear quantile regression estimator adjusted to the case of longitudinal data. Different weights and types of CIs are used and compared by computer simulation using a logistic growth function and error terms following an AR(1) model. The results indicate that bias correction reduces the bias of a point estimator but fails for CI calculations. A bootstrap percentile method and a normal approximation method perform well for two weights when used without bias correction. Taking both coverage and lengths of CIs into consideration, a non-bias-corrected percentile method with an unweighted estimator performs best.     

Uniform Test for Predictive Regression With AR Errors

Testing predictability is of importance in economics and finance. Based on a predictive regression model with independent and identically distributed errors, some uniform tests have been proposed in the literature without distinguishing whether the predicting variable is stationary or nearly integrated. In this article, we extend the empirical likelihood methods of Zhu, Cai, and Peng with independent errors to the case of an AR error process. Again, the proposed new tests do not need to know whether the predicting variable is stationary or nearly integrated, and whether it has a finite variance or an infinite variance. A simulation study shows the new methodologies perform well in finite sample.     

A modified test for testing exponentiality using transformed data

In this article, we present a test for testing uniformity. Based on the test, we provide a test for testing exponentiality. Empirical critical values for both the tests are computed. Both the tests are compared with the tests proposed by Noughabi and Arghami [H. Alizadeh Noughabi, and N.R. Arghami, Testing exponentiality using transformed data, J. Statist. Comput. Simul. 81 (4) (2011), pp. 511–516] using simulation experiments for a wide class of alternatives. The tests possess attractive power properties.