The nested joint clustering via Dirichlet process mixture model

This article focuses on the clustering problem based on Dirichlet process (DP) mixtures. To model both time invariant and temporal patterns, different from other existing clustering methods, the proposed semi-parametric model is flexible in that both the common and unique patterns are taken into account simultaneously. Furthermore, by jointly clustering subjects and the associated variables, the intrinsic complex shared patterns among subjects and among variables are expected to be captured. The number of clusters and cluster assignments are directly inferred with the use of DP. Simulation studies illustrate the effectiveness of the proposed method. An application to wheal size data is discussed with an aim of identifying novel temporal patterns among allergens within subject clusters.     

Assessing the market values of soccer players – a robust analysis of data from German 1. and 2. Bundesliga

The paper examines to what extent a player's market value depends on his skills. Therefore, a data set covering 28 performance measures and the market values of about 493 players from 1. and 2. German Bundesliga is analysed. Applying robust analysis techniques, we are able to robustly estimate market values of soccer players. The results show (1) that there are significantly underrated and overrated players and (2) that a player's affiliation to a certain team may contribute to his market value. We conclude that a club's reputation affects the market values of its players and that star players are in tendency overrated.     

Quantile regression for large-scale data via sparse exponential transform method

In recent decades, quantile regression has received much more attention from academics and practitioners. However, most of existing computational algorithms are only effective for small or moderate size problems. They cannot solve quantile regression with large-scale data reliably and efficiently. To this end, we propose a new algorithm to implement quantile regression on large-scale data using the sparse exponential transform (SET) method. This algorithm mainly constructs a well-conditioned basis and a sampling matrix to reduce the number of observations. It then solves a quantile regression problem on this reduced matrix and obtains an approximate solution. Through simulation studies and empirical analysis of a 5% sample of the US 2000 Census data, we demonstrate efficiency of the SET-based algorithm. Numerical results indicate that our new algorithm is effective in terms of computation time and performs well for large-scale quantile regression.     

Small‐sphere distributions for directional data with application to medical imaging

We propose novel parametric concentric multi‐unimodal small‐subsphere families of densities for p ? 1 ≥ 2‐dimensional spherical data. Their parameters describe a common axis for K small hypersubspheres, an array of K directional modes, one mode for each subsphere, and K pairs of concentrations parameters, each pair governing horizontal (within the subsphere) and vertical (orthogonal to the subsphere) concentrations. We introduce two kinds of distributions. In its one‐subsphere version, the first kind coincides with a special case of the Fisher–Bingham distribution, and the second kind is a novel adaption that models independent horizontal and vertical variations. In its multisubsphere version, the second kind allows for a correlation of horizontal variation over different subspheres. In medical imaging, the situation of p ? 1 = 2 occurs precisely in modeling the variation of a skeletally represented organ shape due to rotation, twisting, and bending. For both kinds, we provide new computationally feasible algorithms for simulation and estimation and propose several tests. To the best knowledge of the authors, our proposed models are the first to treat the variation of directional data along several concentric small hypersubspheres, concentrated near modes on each subsphere, let alone horizontal dependence. Using several simulations, we show that our methods are more powerful than a recent nonparametric method and ad hoc methods. Using data from medical imaging, we demonstrate the advantage of our method and infer on the dominating axis of rotation of the human knee joint at different walking phases.     

Graphical representation of survival curves in the presence of time-dependent categorical covariates with application to liver transplantation

Graphical representation of survival curves is often used to illustrate associations between exposures and time-to-event outcomes. However, when exposures are time-dependent, calculation of survival probabilities is not straightforward. Our aim was to develop a method to estimate time-dependent survival probabilities and represent them graphically. Cox models with time-dependent indicators to represent state changes were fitted, and survival probabilities were plotted using pre-specified times of state changes. Time-varying hazard ratios for the state change were also explored. The method was applied to data from the Adult-to-Adult Living Donor Liver Transplantation Cohort Study (A2ALL). Survival curves showing a ‘split’ at a pre-specified time t allow for the qualitative comparison of survival probabilities between patients with similar baseline covariates who do and do not experience a state change at time t. Time since state change interactions can be visually represented to reflect changing hazard ratios over time. A2ALL study results showed differences in survival probabilities among those who did not receive a transplant, received a living donor transplant, and received a deceased donor transplant. These graphical representations of survival curves with time-dependent indicators improve upon previous methods and allow for clinically meaningful interpretation.     

Semiparametric regression of clustered current status data

This paper discusses regression analysis of clustered current status data under semiparametric additive hazards models. In particular, we consider the situation when cluster sizes can be informative about correlated failure times from the same cluster. To address the problem, we present estimating equation-based estimation procedures and establish asymptotic properties of the resulting estimates. Finite sample performance of the proposed method is assessed through an extensive simulation study, which indicates the procedure works well. The method is applied to a motivating data set from a lung tumorigenicity study.     

On Bartlett correction of empirical likelihood for regularly spaced spatial data

Bartlett correction constitutes one of the attractive features of empirical likelihood because it enables the construction of confidence regions for parameters with improved coverage probabilities. We study the Bartlett correction of spatial frequency domain empirical likelihood (SFDEL) based on general spectral estimating functions for regularly spaced spatial data. This general formulation can be applied to testing and estimation problems in spatial analysis, for example testing covariance isotropy, testing covariance separability as well as estimating the parameters of spatial covariance models. We show that the SFDEL is Bartlett correctable. In particular, the improvement in coverage accuracies of the Bartlett‐corrected confidence regions depends on the underlying spatial structures. The Canadian Journal of Statistics 47: 455–472; 2019 © 2019 Statistical Society of Canada     

Learning from a lot: Empirical Bayes for high‐dimensional model‐based prediction

Empirical Bayes is a versatile approach to “learn from a lot” in two ways: first, from a large number of variables and, second, from a potentially large amount of prior information, for example, stored in public repositories. We review applications of a variety of empirical Bayes methods to several well‐known model‐based prediction methods, including penalized regression, linear discriminant analysis, and Bayesian models with sparse or dense priors. We discuss “formal” empirical Bayes methods that maximize the marginal likelihood but also more informal approaches based on other data summaries. We contrast empirical Bayes to cross‐validation and full Bayes and discuss hybrid approaches. To study the relation between the quality of an empirical Bayes estimator and p, the number of variables, we consider a simple empirical Bayes estimator in a linear model setting. We argue that empirical Bayes is particularly useful when the prior contains multiple parameters, which model a priori information on variables termed “co‐data”. In particular, we present two novel examples that allow for co‐data: first, a Bayesian spike‐and‐slab setting that facilitates inclusion of multiple co‐data sources and types and, second, a hybrid empirical Bayes–full Bayes ridge regression approach for estimation of the posterior predictive interval.     

Linear scalar-on-surface random effects regression models

Many research fields increasingly involve analyzing data of a complex structure. Models investigating the dependence of a response on a predictor have moved beyond the ordinary scalar-on-vector regression. We propose a regression model for a scalar response and a surface (or a bivariate function) predictor. The predictor has a random component and the regression model falls in the framework of linear random effects models. We estimate the model parameters via maximizing the log-likelihood with the ECME (Expectation/Conditional Maximization Either) algorithm. We use the approach to analyze a data set where the response is the neuroticism score and the predictor is the resting-state brain function image. In the simulations we tried, the approach has better performance than two other approaches, a functional principal component regression approach and a smooth scalar-on-image regression approach.     

A general central limit theorem and a subsampling variance estimator for α‐mixing point processes

We establish a central limit theorem for multivariate summary statistics of nonstationary α‐mixing spatial point processes and a subsampling estimator of the covariance matrix of such statistics. The central limit theorem is crucial for establishing asymptotic properties of estimators in statistics for spatial point processes. The covariance matrix subsampling estimator is flexible and model free. It is needed, for example, to construct confidence intervals and ellipsoids based on asymptotic normality of estimators. We also provide a simulation study investigating an application of our results to estimating functions.